Abstract: A method includes storing technical models in a network-accessible model repository. Each technical model is labeled with descriptive metadata and comprises one or more model views labeled with functional metadata. A request is received from a stakeholder device, the request specifying descriptive attributes and functional attributes applied to an associated stakeholder. Technical model(s) are retrieved based on the descriptive metadata labelling the retrieved technical models being determined to satisfy the descriptive attributes included in the request. For each retrieved technical model, one or more model views are compiled based on the functional metadata labelling the compiled model view being determined to satisfy the functional attributes included in the request.

Abstract: This disclosure describes a system for protection of the bottle or carboys during freezing, storage or transport, and thawing. The system described herein is designed to enable high heat transfer rates under certain conditions, thus enabling to freeze or thaw the biopharmaceutical solutions at optimal rates, without disassembling the protective structure. This disclosure describes a system configured to receive a bottle or carboy filled with biopharmaceutical solutions for freezing, transport and thawing. This system comprises five main parts: a lid; a top cover; a multi-shape compatible top holder; a multi-shape compatible bottom holder and a bottom cover. This system has an opening in the bottom below the container that allows air to be driven through the walls of the bottle and through a side vent. The airflow passage in the system, allows the use of the system for freezing (cold air) or thawing (hot air) while providing physical protection.

Abstract: A dynamic user interface is configured to generate two types of information that may be generated by sophisticated computer systems such as expert systems and/or artificial intelligence. These types and include a “what if” prediction that illustrates probable outcomes from alternative actions, and a “similarity” analysis which shows a user how adjustments to input data may affect the resulting predictions. The “what if” prediction provides users guidance as to what actions may be most beneficial. The “similarity” analysis helps the users understand consequences of medical decisions.

Abstract: The present subject matter relates to a method of predicting a traffic behaviour in a road system, comprising the following steps carried out by at least one processor connected to a database, which contains a set of traffic profiles: clustering the traffic profiles; calculating a significance value; if the significance value of a tag is higher than a threshold value, assigning this tag as a characteristic vector to this cluster; receiving a request having one or more request tags; determining a cluster by means of matching the request tag/s to the characteristic vectors of the clusters; and outputting a predicted traffic behaviour based on the determined cluster.

Abstract: The present invention relates to a new polypeptide with xylanase activity, the nucleotide sequence encoding it, an ingredient containing said polypeptide, and a process for preparing a food product which comprises adding said ingredient to the preparation. This new polypeptide with xylanase activity is particularly useful for the baking industry, endowing doughs with greater elasticity, less tenacity, formation of a stronger gluten network with less water, shorter mixing time, and greater volume of the final product.

Abstract: The present subject matter relates to a method of predicting a traffic behaviour in a road system, comprising the following steps carried out by at least one processor connected to a database, which contains a set of traffic profiles: clustering the traffic profiles; for each cluster, determining a dissimilarity measure; receiving a request having one or more request tags; checking whether all request tags match one of the characteristic vectors of the clusters, and if so, outputting a predicted traffic behaviour, else, eliminating one of the request tags from the request and returning to the beginning of said step of checking.

Abstract: The present subject matter relates to a method of predicting a traffic behaviour in a road system, comprising the following steps carried out by at least one processor connected to a database, which contains a set of traffic profiles: clustering the traffic profiles; for each cluster, determining a dissimilarity measure; receiving a request having one or more request tags; checking whether all request tags match one of the characteristic vectors of the clusters, and if so, outputting a predicted traffic behaviour, else, eliminating one of the request tags from the request and returning to the beginning of said step of checking.

Abstract: The present subject matter relates to a method of predicting a traffic behaviour in a road system, comprising the following steps carried out by at least one processor connected to a database, which contains a set of traffic profiles: clustering the traffic profiles; calculating a significance value; if the significance value of a tag is higher than a threshold value, assigning this tag as a characteristic vector to this cluster; receiving a request having one or more request tags; determining a cluster by means of matching the request tag/s to the characteristic vectors of the clusters; and outputting a predicted traffic behaviour based on the determined cluster.

Abstract: A system and method for is provided for operation of an orthopedic system. The system includes a load sensor for converting an applied pressure associated with a force load on an anatomical joint, and an inertial sensing device configured to measure alignment. The inertial sensing device provides alignment measurement data to measure alignment. An ultrasonic transducer, MEMs microphone, electromagnets, optical elements, metallic objects or other transducers can be configured to convert or convey a physical movement to an electrical signal and support measurement of muscular-skeletal alignment. The load sensor can be used to measure load magnitude and position of load of an applied load by the muscular-skeletal system.

Abstract: A system and method for is provided for operation of an orthopedic system. The system includes a load sensor for converting an applied pressure associated with a force load on an anatomical joint, and an inertial sensing device configured to measure alignment. The inertial sensing device provides alignment measurement data to measure alignment. An ultrasonic transducer, MEMs microphone, electromagnets, optical elements, metallic objects or other transducers can be configured to convert or convey a physical movement to an electrical signal and support measurement of muscular-skeletal alignment. The load sensor can be used to measure load magnitude and position of load of an applied load by the muscular-skeletal system.

Abstract: A system and method for is provided for operation of an orthopedic system. The system includes a load sensor for converting an applied pressure associated with a force load on an anatomical joint, and an ultrasonic device for creating a low-power short-range ultrasonic sensing field within proximity of the load sensing unit for assessing alignment. The system can adjust a strength and range of the ultrasonic sensing field according to position. It can report audible and visual information associated with the force load and alignment. Other embodiments are disclosed.

Abstract: A portable measurement system is provided comprising a probe, two trackers, a receiver and a pod. A user interface control captures a location and position of the probe in a three-dimensional sensing space with respect to a coordinate system of the receiver from time of flight waveform analysis. The system suppresses a ringing portion of the received ultrasonic and minimizes distortion associated with ultrasonic transducer ring-down during high-resolution position tracking of the probe and the two trackers. Media is presented according to a customized use of the probe and two trackers during an operation workflow.

Abstract: A system and method for is provided for operation of an orthopedic system. The system includes a load sensor for converting an applied pressure associated with a force load on an anatomical joint, and an ultrasonic device for creating a low-power short-range ultrasonic sensing field within proximity of the load sensing unit for assessing alignment. The system can adjust a strength and range of the ultrasonic sensing field according to position. It can report audible and visual information associated with the force load and alignment. Other embodiments are disclosed.

Abstract: A bone fastener includes a head, an elongated shank defining a longitudinal axis having a proximal end and a distal end. The proximal end is connected to the head and the elongated shank has an inner surface defining a longitudinal cavity disposed along the longitudinal axis and at least one transverse cavity positioned in the elongated shank. The inner surface defining the transverse cavity and the elongated cavity as well as the outer surface of the elongated shank has bone conductive material disposed thereon so as to promote bone growth into the transverse cavities, elongated cavity and on the surface of the elongated shank in order to secure the bone fastener to bone. The distal end of the bone fastener can be configured to have cutting features that cut into bone and self-pack the elongated cavity with autograft material as it is inserted into bone.

Abstract: A method for determining orthopedic alignment is provided. The method includes monitoring a first and second sequence of signals transmitted from the first device to a second device, estimating a location of the first device from sensory measurements of the signals at respective sensors on the second device, calculating a set of phase differences, weighting a difference of an expected location and estimated location of the first device with the set of phase differences to produce a relative displacement, and reporting a position of an orthopedic instrument coupled to the first device based on the relative displacement.

Abstract: A configurable check and balance system is provided to assess and report orthopedic measurements, including bone cut angles, trial inserts, extension gaps and prosthetic fit. The system can be configured for cut-check, trial-check, alignment and balance, dynamic distraction, and prosthetic trial fit. The measurements can be provided with respect to an anatomical coordinate system defined according to a positioning of a sensorized mechanical plate with respect to one or more referenced anatomical landmarks. In one example, the cut-check provides measurement of varus/valgus angle and anterior/posterior slope for distal femur cuts and proximal tibia cuts. The cut-check permits a surgeon to check bone cuts made by mechanical jigs, guides or patient specific implants (PSI). It also provides distance measurements. Other embodiments are also disclosed.

Abstract: A method for determining orthopedic alignment is provided. The method includes monitoring a first and second sequence of signals transmitted from the first device to a second device, estimating a location of the first device from sensory measurements of the signals at respective sensors on the second device, calculating a set of phase differences, weighting a difference of an expected location and estimated location of the first device with the set of phase differences to produce a relative displacement, and reporting a position of an orthopedic instrument coupled to the first device based on the relative displacement.

Abstract: A portable measurement system is provided including a probe, a user interface control and a receiver. The probe includes a plurality of ultrasonic transducers that emit ultrasonic waveforms for creating a three-dimensional sensing space. The user interface control captures a location and position of the probe in the three-dimensional sensing space. The receiver includes a plurality of microphones to capture the ultrasonic waveforms transmitted from the probe to produce captured ultrasonic waveforms and a digital signal processor that digitally samples the captured ultrasonic waveforms and tracks a relative location and movement of the probe with respect to the receiver in the three-dimensional ultrasonic sensing space from time of flight waveform analysis. Embodiments are demonstrated with respect to hip replacement surgery, but other embodiments are contemplated.

Abstract: A vertebral rod includes a first elongated section, a second elongated section and an intermediate section disposed between the first section and the second section. The intermediate section has an inner surface and opposing end portions that define an open portion. A removable element extends from one of the first, second or intermediate sections and is disposable adjacent the opposing end portions. The element is configured to prevent engagement of the opposing end portions. A resistance member is configured for disposal with the intermediate section and engaging at least a portion of the inner surface. A method of manufacture is also disclosed.

Abstract: A portable measurement system is provided comprising a probe, two trackers, a receiver and a pod. A user interface control captures a location and position of the probe in a three-dimensional sensing space with respect to a coordinate system of the receiver from time of flight waveform analysis. The system suppresses a ringing portion of the received ultrasonic and minimizes distortion associated with ultrasonic transducer ring-down during high-resolution position tracking of the probe and the two trackers. Media is presented according to a customized use of the probe and two trackers during an operation workflow.