Patents by Inventor Carlos J. Alméciga-Diaz

Carlos J. Alméciga-Diaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DELIVERY OF THERAPEUTIC AGENTS TO THE BONE
    Publication number: 20110311487
    Abstract: This invention relates to compositions and methods of delivering therapeutic agents to bone. More specifically, the invention relates to endowing a large molecule vectors i.e., adeno virus, retrovirus, liposomes, micelles, natural and synthetic polymers, or combinations thereof, with the ability to target bone tissue in vivo and with improved stability in the blood, by attaching multiple copies of acid amino acid peptides. One preferred embodiment of the invention relates to endowing an adeno-associated virus (AAV) vector with the ability to target bone-tissue in vivo and improve its stability, by the addition of multiple acidic amino acid peptides attached to the capsid of the viral vector.
    Type: Application
    Filed: May 20, 2011
    Publication date: December 22, 2011
    Applicant: Saint Louis University
    Inventors: Shunji Tomatsu, Adriana M. Montaño-Suarez, Carlos J. Alméciga-Diaz, Luis Barrera
  • Delivery of therapeutic agents to the bone
    Patent number: 7972593
    Abstract: This invention relates to compositions and methods of delivering therapeutic agents to bone. More specifically, the invention relates to endowing a large molecule vectors i.e., adeno virus, retrovirus, liposomes, micelles, natural and synthetic polymers, or combinations thereof, with the ability to target bone tissue in vivo and with improved stability in the blood, by attaching multiple copies of acid amino acid peptides. One preferred embodiment of the invention relates to endowing an adeno-associated virus (AAV) vector with the ability to target bone-tissue in vivo and improve its stability, by the addition of multiple acidic amino acid peptides attached to the capsid of the viral vector.
    Type: Grant
    Filed: July 3, 2009
    Date of Patent: July 5, 2011
    Assignee: Saint Louis University
    Inventors: Shunji Tomatsu, Adriana Montaño-Suarez, Carlos J. Alméciga-Diaz, Luis Barrera
  • DELIVERY OF THERAPEUTIC AGENTS TO THE BONE
    Publication number: 20100008979
    Abstract: This invention relates to compositions and methods of delivering therapeutic agents to bone. More specifically, the invention relates to endowing a large molecule vectors i.e., adeno virus, retrovirus, liposomes, micelles, natural and synthetic polymers, or combinations thereof, with the ability to target bone tissue in vivo and with improved stability in the blood, by attaching multiple copies of acid amino acid peptides. One preferred embodiment of the invention relates to endowing an adeno-associated virus (AAV) vector with the ability to target bone-tissue in vivo and improve its stability, by the addition of multiple acidic amino acid peptides attached to the capsid of the viral vector.
    Type: Application
    Filed: July 3, 2009
    Publication date: January 14, 2010
    Applicant: Saint Louis University
    Inventors: Shunji Tomatsu, Adriana M. Montaño-Suarez, Carlos J. Alméciga-Diaz, Luis Barrera