Patents by Inventor Carlos Jaime Camacho

Carlos Jaime Camacho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecules that specifically inhibit TNF-induced NF-KB inflammation pathway
    Patent number: 11858877
    Abstract: Provided herein are small molecules that specifically inhibit TNF-induced nuclear factor kB (NF-kB) inflammation pathway. Also provided are methods of screening compounds to identify molecules that specifically inhibit a TNF-induced NF-kB inflammation pathway, methods of inhibiting TNF-induced NF-kB inflammation pathway, and methods of preventing formation of mature TNFR1 complex.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: January 2, 2024
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Carlos Jaime Camacho, Robin E. C. Lee
  • NEUROPROTECTIVE DISRUPTION OF KV2.1/SYNTAXIN INTERACTION BY SMALL MOLECULES
    Publication number: 20210322383
    Abstract: Disclosed herein are small molecule compounds capable of disrupting Kv2.1-syntaxin binding. The compounds are useful for treating a variety of neurological disorders, diseases, and injuries.
    Type: Application
    Filed: July 31, 2019
    Publication date: October 21, 2021
    Inventors: Elias AIZENMAN, Carlos Jaime CAMACHO
  • SMALL MOLECULES THAT SPECIFICALLY INHIBIT TNF-INDUCED NF-KB INFLAMMATION PATHWAY
    Publication number: 20200325098
    Abstract: Provided herein are small molecules that specifically inhibit TNF-induced nuclear factor kB (NF-kB) inflammation pathway. Also provided are methods of screening compounds to identify molecules that specifically inhibit a TNF-induced NF-kB inflammation pathway, methods of inhibiting TNF-induced NF-kB inflammation pathway, and methods of preventing formation of mature TNFR1 complex.
    Type: Application
    Filed: February 24, 2020
    Publication date: October 15, 2020
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Carlos Jaime Camacho, Robin E. C. Lee