Patents by Inventor Carlos Jimenez Romero

Carlos Jimenez Romero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plakortinic acids A and B: cytotoxic cycloperoxides with a unique bicyclo[4.2.0]octene unit from sponges of the genera and
    Patent number: 11198678
    Abstract: Plakortinic acids A (2) and B (3), two polyketide endoperoxides having an unprecedented bicyclo[4.2.0]octene unit, were isolated as minor constituents from the sponge-sponge symbiotic association Plakortis halichondrioides-Xestospongia deweerdtae from Puerto Rico, along with the known epiplakinic acid F (1). The molecular structures of 2 and 3 were determined mainly on the basis of NMR spectroscopy. Due to the structural similarities, 2 and 3 are thought to be biosynthetically related to 1. Biological screening for cytotoxic activity against two human tumor cell lines revealed that these novel metabolites are very active at low to sub-micro molar concentration.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: December 14, 2021
    Assignee: University of Puerto Rico
    Inventors: Abimael D. Rodriguez Pierluissi, Carlos Jimenez Romero