Abstract: A measuring apparatus for measuring the thickness of slices taken from biological tissue samples by a microtome. The apparatus integrates a digital micrometer, a drive motor, sensing and control circuitry, and a mounting plate, and is designed to be attached to the top of a Krumdieck or similarly designed microtome for measuring the thickness of slices produced. The apparatus is designed so that the spindle of the micrometer is positioned in vertical alignment with the tissue well and plunger of the microtome. The user initiates downward movement of the spindle by depressing a down switch and control circuitry actuates the drive motor to advance the spindle of the micrometer down toward the top of the plunger until the bottom surface of the spindle contacts the plunger. The bottom surface of the spindle is electrically connected to a power source, and the plunger is electrically connected to the control circuitry.

Abstract: A method and apparatus for preparing tissue samples for subsequent slicing in a microtone, utilizing a thermally transmissive body and removable mold heads to facilitate encapsulation of tissue samples in a gelatinous substance so that the samples may be selectively oriented for proper slicing in the microtone.

Abstract: A tissue slicer having a reciprocating tissue holding blade. A mechanically activated pumping system for flushing liquid medium past a cutting blade into a collection trap. The cutting blade is moved by a reciprocation drive system adjacent and above the cutting blade. The entire slicing assembly is fully autoclavable.

Abstract: A biological tissue slicer having improvements therein which enable an inexperienced operator to rapidly prepare minimally traumatized tissue slices of excellent viability and of very uniform shape and dimension. The improvements limit contact of the cutting edge of the blade with the tissue to avoid irregular surfaces and trauma to the tissue sample. The device utilizes two pins and one or more magnets to hold the blade to a rapidly reciprocally moving blade holder such that uniform tissue slices of defined dimensions are produced by eliminating excessive lateral and vertical movement of the blade.