Abstract: An anti-cancer compound is a compound having the following structural formula: or a pharmaceutically acceptable salt thereof.

Abstract: A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof.

Abstract: A method of alleviating or treating a condition which can be alleviated or treated by administering hyoscyamine comprises administering to a subject in need thereof a pharmaceutical dosage form which comprises at least one of hyoscyamine and a pharmaceutically acceptable salt thereof. The dosage form comprises two or more hyoscyamine formulations, at least one of the formulations being an immediate release formulation and at least one other one being a controlled release formulation.

Abstract: A pharmaceutical dosage form which comprises diphenhydramine and/or a pharmaceutically acceptable salt thereof and at least one second drug. The dosage form provides a plasma concentration within the therapeutic range of the at least one second drug over a period which is coextensive with a substantial part of the period over which the dosage form provides a plasma concentration within the therapeutic range of diphenhydramine or salt thereof. This Abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.

Abstract: A pharmaceutical dosage form which comprises phenylepherine or a pharmaceutically acceptable salt thereof and a second drug. The dosage form provides a plasma concentration within the therapeutic range of the second drug over a period which is coextensive with at least about 70% of the period over which the dosage form provides a plasma concentration within the therapeutic range of phenylepherine. This abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.

Abstract: The invention relates to a pulling machine for unloading and laying railway tracks, which moves by means of caterpillar tracks running next to the sleepers arranged on the setting bed, with the rail on the provisional supports arranged on the sleepers. The machine comprises a cabin and two caterpillar tracks and includes, in its rear tractor part, a pulling slide that comprises a tube with fastening elements, said tube sliding horizontally, actuated by a hydraulic cylinder comprising a piston connected to the tube, via three dismountable metal supports provided with teflon elements for facilitating the sliding, said metal supports being connected to steel elements acted upon by articulated arms generating the vertical movement by means of the action of another hydraulic cylinder, always maintaining the pulling direction. The machine pulls the rails without needing an auxillary track, maintaining the position of the track-laying train.

Abstract: A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof.

Abstract: A method of alleviating or treating a condition which can be alleviated or treated by administering hyoscyamine comprises administering to a subject in need thereof a pharmaceutical dosage form which comprises at least one of hyoscyamine and a pharmaceutically acceptable salt thereof. The dosage form comprises two or more hyoscyamine formulations, at least one of the formulations being an immediate release formulation and at least one other one being a controlled release formulation.

Abstract: A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof.

Abstract: A pharmaceutical dosage form which comprises two or more different hyoscyamine formulations, at least one of the formulations being an immediate release hyoscyamine formulation and at least one other one being a controlled release hyoscyamine formulation. This abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.

Abstract: The invention relates to a pulling machine for unloading and laying railway tracks, which moves by means of caterpillar tracks running next to the sleepers arranged on the setting bed, with the rail on the provisional supports arranged on the sleepers. The machine comprises a cabin and two caterpillar tracks and includes, in its rear tractor part, a pulling slide that comprises a tube with fastening elements, said tube sliding horizontally, actuated by a hydraulic cylinder comprising a piston connected to the tube, via three dismountable metal supports provided with teflon elements for facilitating the sliding, said metal supports being connected to steel elements acted upon by articulated arms generating the vertical movement by means of the action of another hydraulic cylinder, always maintaining the pulling direction. The machine pulls the rails without needing an auxiliary track, maintaining the position of the track-laying train.

Abstract: A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof. This Abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.

Abstract: A capsule for oral administration to a human subject. The capsule comprises at least two different pharmaceutical compositions in granular form. This Abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.

Abstract: The invention provides an electrochemical noise method, apparatus and system for estimating parameters of interest related to corrosion rates of an electrically conductive article, the method comprising: placing a working electrode, a reference electrode, and a counter electrode in an environment of interest; measuring potential at open circuit between the working electrode and the reference electrode over time; placing the working electrode under a potentiostatic control; measuring current between the working electrode and the counter electrode for a predetermined period of time, the period of time of measurements may be extended to include a transient event; and estimating the corrosion rate.

Abstract: Compounds of the following formula: wherein all variables are as defined in the specification. The compounds have cytotoxic properties and can therefore be used in the treatment of malignant tumors.

Abstract: Compounds having formula (I) wherein R3, R4, R7 and R8 are independently selected from the group consisting of hydrogen, lower alkyl, halogen, amine, mono(lower)alkylamine, di(lower)alkylamine, phenyl, or substituted phenyl possess antitumor activity and are new with the exception of the compound in which R3, R4, R7, R8 are all hydrogen and the compound in which R3 and R7 are hydrogen, R4 is chlorine, and R8 is a 2-nitrophenyl group.

Abstract: Compounds of formula (I), wherein X is selected from the group consisting of O, and NR3, where R3 represents a lower alkyl group; Y is selected from the group consisting of CH and N; R1 and R2 are independently selected from the group consisting of NH2, NHR4 and NR52, where R4 and R5 each represent a lower alkyl group, or R1 and R2 together represent a cycle selected from (a), (b) and (c), wherein R6, R7 and R8 are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.

Abstract: 1 Compounds having formula (I) wherein R3, R4, R7, and R8 are independently selected from the group consisting of hydrogen, lower alkyl, halogen, amine, mono(lower)alkylamine, di(lower)alkylamine, phenyl, or substituted phenyl possess antitumor activity and are new with the exception of the compound in which R3, R4, R7, R8 are all hydrogen and the compound in which R3 and R7 are hydrogen, R4 chlorine, and R8 is a 2-nitrophenyl group.