Abstract: A device is provided to rapidly, safely, efficiently and effectively close tissue defects created to access operative sites in a patients body. The device comprises an elongated body with its features in profile to allow use through conduits such as trocars which can be removed over the device. The device has diametrically opposed pivoting extensions which provide a target for flexible needles to attach to suture and provide protection for all vital structures in the body. Once the pivoting extensions are past the innermost layer adjacent to the tissue defect the flexible needles are advanced through the tissue to obtain an adequate and proper amount of tissue to allow for a strong closure. The device leaves a suture behind which can then be tied to close the tissue defect.

Abstract: Described here are polymer compositions, methods, and systems for reinforcing a wall of a heart. The polymer compositions may be adapted to form networks, e.g., cross-linked networks, semi-interpenetrating networks, or interpenetrating networks, and placed within the pericardial space or on one or more pericardial tissues. The mechanical properties of the polymer compositions or networks derived therefrom may then be employed to reinforce a heart wall to prevent dilatation of a chamber of the heart and/or expansion of an infarct, e.g., to treat or prevent congestive or chronic heart failure.

Abstract: Devices and methods are provided for the treatment of obstructive sleep apnea. An implantable device is inserted into the tongue. The implantable device is a flexible elongated structure, which may be a curved or jointed filament; of a sufficient length and diameter to provide support, when implanted, sufficient to restrain obstructive movement of the tongue during sleep.