Patents by Inventor Carlos Monserrat Vidal

Carlos Monserrat Vidal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted imidazo 1,2a}azines as selective inhibitors of cox-2
    Patent number: 6670365
    Abstract: The invention refers to new compounds of formula (I), wherein A and B are selected from the group consisting of N and CH, with the condition that when A is N, B is N; R1 is selected from the group consisting of CH3 and NH2; R2 and R3 are selected from the group consisting of H, CH3, Br, Cl, COCH3 and OCH3; and R4, R5 and R6, are selected from the group consisting of H, F, Cl, Br, (C1-C3)-alkyl, trifluoromethyl, (C1-C3)-alkoxy and trifluoromethoxy. Compounds of formula (I) are prepared by reaction of a substituted aminoazine with a substituted 2-bromo-2-(4-R1-sulfonylphenyl)-1-phenylethanone in a polar solvent. These new compounds inhibit COX-2 with high selectivity over COX-1. They are useful for the treatment of inflamation and/or cyclooxygenase-mediated diseases, having the additional advantage of a reduced potencial for ulcerogenic effects.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: December 30, 2003
    Assignee: Laboratorios S.A.L.V.A.T., S.A.
    Inventors: Carles Farrerons Gallemi, Ignacio-José Miquel Bono, Ana Maria Fernandez Serrat, Carlos Monserrat Vidal, Carmen Lagunas Arnal, Ferran Gimenez Guasch, Andrés Fernandez Garcia