Abstract: Non-invasive Ocular Drug Delivery Insert Technology. The invention concerns an ocular insert which is a new biocompatible polymer-based controlled drug delivery system (CDDS) applicable to a variety of drugs and other compounds for the treatment of different ocular pathologies. This ocular insert allows releasing of at least one drug under suitable concentration levels during suitable periods of time. The device may be inserted in the lower or upper fornix conjunctiva, in a non-invasive way, meaning that the patient will be able to place the device himself, without intervention of medical specialized staff. The insert of the invention will release the drug in such a controlled rate that will allow the drug release up to 300 days by either a “Fickian” or a linear profile according to the intend purpose or pathology.

Abstract: Improvements to a juice extraction machine, particularly a commercial-scale fruit juice extraction machine that is extremely light and compact for very easy handling and transportation, which is noteworthy for its unusual construction configuration that includes, among other items, a swing lidded waste-bin on its front whose walls are close to the peeler cups when closed, allowing easy removal of wastes such as pith, pulp and peel when open.

Abstract: Non-invasive Ocular Drug Delivery Insert Technology. The invention concerns an ocular insert which is a new biocompatible polymer-based controlled drug delivery system (CDDS) applicable to a variety of drugs and other compounds for the treatment of different ocular pathologies. This ocular insert allows releasing of at least one drug under suitable concentration levels during suitable periods of time. The device may be inserted in the lower or upper fornix conjunctiva, in a non-invasive way, meaning that the patient will be able to place the device himself, without intervention of medical specialized staff. The insert of the invention will release the drug in such a controlled rate that will allow the drug release up to 300 days by either a “Fickian” or a linear profile according to the intend purpose or pathology.

Abstract: Embodiments of subcombination and the fruit extraction device of the present invention provide for fruit juice extraction where synchronized and concentric elements press a fruit, such as an orange, without crushing the peel, by this avoiding the dispersion of acids from the peel, favoring the retention of juice having lower acid levels. Embodiments of the subcombination and the fruit extraction device of which it is a portion shear the peel in multiple slivers, at the same time compressing the fruit. In an exemplary embodiment, a subcombination comprises a fixed and a mobile peeler, each having radially extending blades that form a space within which a fruit may be positioned for juice extraction, and a perforating filtering tube within the fixed peeler, and a piston adapted to pass through the lumen of the perforating filtering tube to cyclically clean it of the residues of a compressed fruit prior to extraction of the next fruit.

Abstract: A fruit juice extraction apparatus comprising: a chassis having mounted thereon a juice extractor which has a container for storing the fruit, the container having an aperture therein for allowing articles of fruit to be deposited between two concave hemispheres; drive motor for actuator for forcing the first concave hemispheres against the second concave hemispheres, thereby pressing an article of fruit deposited between said hemispheres; the first concave hemisphere having a central pin and the second concave hemisphere a perforating tube for the extraction of juice from said article of fruit, whereby the solid residue is deposited in a receptacle and the liquid is passed through a filter and then falls into a reservoir which has outlet ports therein, the perforating tube having multiple transverse slits of increasing diameter from inside to outside.

Abstract: Modular fruit juice extraction apparatuses and systems are provided that comprise, for example, a linear actuator (2) effective to drive, by back and forth motion, a moveable peeler cup (4) in communication with each of two ends of the extraction apparatus. In such embodiment, each moveable peeler cup (4), comprising concave and radially cut hemispheres, moves against a respective fixed peeler cup (3), and thereby compresses a fruit (19) contained therein to obtain its juice, which passes through a filtering device (7) disposed in each respective fixed peeler cup (3). A plunger (8) is variously driven through the filtering device (7) to remove the fruit core (13). Other embodiments include an embodiment in which a linear actuator (202) drives both external moveable peeler cups (203) and internal moveable peeler cups (204).

Abstract: A rotary-to-reciprocating linear drive conversion device is linked to drive moveable elements of a multi-unit fruit juice extraction machine. At least two co-rotating members drive a reciprocating transverse member by means of respective protruding force-transfer posts of the co-rotating members rotating while disposed to slidingly engage in the groove, so that the rotation of the co-rotating members results in reciprocal movement of the transverse member, and of elements of the multi-unit fruit extraction machine linked thereto. The elements of the multi-unit fruit extraction machine include opposing sets of a plurality of matched peeler cups, forming matched pairs of opposing peeler cups, each peeler cup comprising a plurality of outwardly extending blades cooperatively intermeshing with a corresponding plurality of outwardly extending blades of an opposing peeler cup of the matched pair, one of said cups additionally comprising a filter device.

Abstract: A juicing apparatus is provided in which a single actuating element (2) drives a multiple number, such as three, of movable peeler cups (4), against their respective paired or matched fixed peeler cups (3), in a manner such to simultaneously provide for the extraction of juice from a number of fruit (19), one in each of the matched pairs of fixed and movable peeler cups (3, 4), said matched pairs of peeler cups being subjected to substantially the same force and reciprocating action as the other. Blades (38, 39) of the fixed and movable peeler cups (3, 4) engage the peel of the fruit (19) and provide for its removal. In certain embodiments, within each fixed peeler cup (3) is a filtering device (7) comprising a sharpened end (43) that meets the fruit (19), and a plurality of slits in the wall(s) of the filtering device for passage of juice compressed from the fruit.

Abstract: A fruit juice extraction apparatus for processing citrus fruit in general, without manual contact, comprising a tubular chassis having mounted thereon an extraction box affixed to a gearmotor for actuating an crank and rod assembly which dislocates one concave hemisphere against another concave hemisphere, thereby pressing fruit released by a trigger positioned on an opening in a tray in which one of the concave hemispheres has a central pin and on the other a perforating tube for the extraction of the juice, the solid residues of the fruit being released into a receptacle and the liquid passing through a filter, then falling into a reservoir which has outlet ports therein.

Abstract: A fruit juice extraction apparatus for processing citrus fruit in general, without manual contact, comprising a tubular chassis having mounted thereon an extraction box affixed to a gearmotor for actuating an crank and rod assembly which dislocates one concave hemisphere against another concave hemisphere, thereby pressing fruit released by a trigger positioned on an opening in a tray in which one of the concave hemispheres has a central pin and on the other a perforating tube for the extraction of the juice, the solid residues of the fruit being released into a receptacle and the liquid passing through a filter, then falling into a reservoir which has outlet ports therein, each of the concave hemispheres having its concave surface defined by a plurality of spaced-apart radial blades of at least two different lengths and depending from a base mounted to the chassis.

Abstract: A fruit juice extraction apparatus for processing citrus fruit in general, without manual contact, comprising a tubular chassis having mounted thereon an extraction box affixed to a gearmotor for actuating a sliding assembly which dislocates one concave hemisphere against another concave hemisphere, thereby pressing fruit released by a trigger positioned on an opening in a tray in which one of the concave hemispheres has a fruit peeler and on the other a perforating tube for the extraction of the juice, the solid residues of the fruit being released into a receptacle and the liquid passing through a filter, then falling into a reservoir which has outlet ports therein.

Abstract: A fruit juice extraction apparatus for processing citrus fruit in general, without manual contact, comprising a tubular chassis having mounted thereon an extraction box affixed to a gearmotor for actuating an crank and rod assembly which dislocates one concave hemisphere against another concave hemisphere, thereby pressing fruit released by a trigger positioned on an opening in a tray in which one of the concave hemispheres has a central pin and on the other a perforating tube for the extraction of the juice, the solid residues of the fruit being released into a receptacle and the liquid passing through a filter, then falling into a reservoir which has outlet ports therein.