Abstract: The present invention relates to a SIRT1 activator for use in promoting and/or enhancing sperm capacitation process in mammals, a specific process for these cells. The disclosure also relates to a compound and a kit comprising the SIRT1 activator. The present invention further discloses the use of a commercially available SIRT1 activator, YK-3-237, as an additive or as a new ingredient to any sperm media already existing in the market to promote the sperm capacitation process, promoting fertilization in mammals.

Abstract: The present invention refers to field of assisted reproductive technologies, in particular to a sperm storage media, and describes mTOR enhancers, preferably the mTOR activator MHY 1485, as supplement for storage media, said supplemented media increasing sperm motility and viability during short-term room temperature storage, while sustaining the metabolic rates, without changing its fertilization potential (capacitation) and DNA integrity.

Abstract: The present invention refers to field of assisted reproductive technologies, in particular to a sperm storage media, and describes mTOR enhancers, preferably the mTOR activator MHY 1485, as supplement for storage media, said supplemented media increasing sperm motility and viability during short-term room temperature storage, while sustaining the metabolic rates, without changing its fertilization potential (capacitation) and DNA integrity.

Abstract: The present invention provides a portable gyroscopic device for the transportation of objects or individuals which comprises: a portable receptacle (A?) which comprises: a frame (1) on which an axis (3) of a gyroscopic element comprising one or more masses or flywheel units (2) is mounted; at least one electric motor (8) which actuates at least one mass or flywheel unit of said gyroscopic element mentioned, a source of electric power (5); and electronic control means (6) to operate said electric motor. Besides, the invention provides a set of portable gyroscopic device and accessories for the transportation of objects or individuals which comprises the portable gyroscopic device according to claims 1 to 1 and a transportation platform (11) which comprises elements for the transportation of said platform which are selected between mechanical bearings, drones, an air cushion and an electromagnetic field.

Abstract: The present invention provides a portable gyroscopic device for the transportation of objects or individuals which comprises: a portable receptacle (A?) which comprises: a frame (1) on which an axis (3) of a gyroscopic element comprising one or more masses or flywheel units (2) is mounted; at least one electric motor (8) which actuates at least one mass or flywheel unit of said gyroscopic element mentioned, a source of electric power (5); and electronic control means (6) to operate: said electric motor. Besides, the invention provides a set of portable gyroscopic device and accessories for the transportation of objects or individuals which comprises the portable gyroscopic device according to claims 1 to 1 and a transportation platform (11) which comprises elements for the transportation of said platform which are selected between mechanical bearings, drones, an air cushion and an electromagnetic field.

Abstract: A money handling apparatus is constituted by a mechanical processing unit configured to mechanically process money, and a manually-handled money storage unit for storing money by a manual handling. The mechanical processing unit includes an inlet for receiving money, a recognition and counting unit configured to recognize and count the money that has been received in the inlet, a mechanically-processed money storage unit configured to store the money, an outlet to which the money fed from the mechanically-processed money storage unit is discharged, and a money transport unit configured to connect these units and portions. The manually-handled money storage unit is not connected to the money transport unit of the mechanical processing unit, and has a structure in which money to be manually managed can be directly stored therein by hand and the stored money can be directly taken out therefrom by hand.

Abstract: A money handling apparatus is constituted by a mechanical processing unit configured to mechanically process money, and a manually-handled money storage unit for storing money by a manual handling. The mechanical processing unit includes an inlet for receiving money, a recognition and counting unit configured to recognize and count the money that has been received in the inlet, a mechanically-processed money storage unit configured to store the money, an outlet to which the money fed from the mechanically-processed money storage unit is discharged, and a money transport unit configured to connect these units and portions. The manually-handled money storage unit is not connected to the money transport unit of the mechanical processing unit, and has a structure in which money to be manually managed can be directly stored therein by hand and the stored money can be directly taken out therefrom by hand.

Abstract: A switching scheme is used during a calibration mode for determining calibration coefficients of each calibrated stage of a pipeline analog-to-digital converter (ADC). A calibrated stage of the pipeline ADC includes an amplifier for amplifying a residue voltage of the stage and a sampling capacitor comprising a plurality of sub-capacitors. The plurality of sub-capacitors have a first terminal connected to an input of amplifier and a second terminal connected to one or more switches that selectively couple the second terminal to the input terminal of the stage, a first reference voltage or a second reference voltage lower than the first reference voltage. During foreground calibration, a number of measurements are taken at an output of the amplifier to determine the calibration coefficient of the calibrated stage.

Abstract: The comformationally highly bent steroid 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) has been found to be a selective antiglucocoriticoid virtually lacking mineralococorticoid or glucocorticoid properties as well as affinity for MR or PR and is used for the treating of diseases associated with an excess of glucocordcoids in the body, such as the Cushing's syndrome or depression.