Patents by Inventor Carlos ROMÁ MATEO

Carlos ROMÁ MATEO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mass spectrometry-based methods for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients
    Patent number: 11740245
    Abstract: The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: August 29, 2023
    Assignees: Centro de Investigación Biomédica en Red (CIBER-ISCIII), Fundación INCLIVA, Universitat de Valencia Estudi General
    Inventors: José Luis García Giménez, Carlos Romá Mateo, Federico V. Pallardó Calatayud
  • MASS SPECTROMETRY-BASED METHODS FOR THE DETECTION OF CIRCULATING HISTONES H3 AND H2B IN PLASMA FROM SEPSIS OR SEPTIC SHOCK (SS) PATIENTS
    Publication number: 20200264190
    Abstract: The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.
    Type: Application
    Filed: November 6, 2017
    Publication date: August 20, 2020
    Inventors: José Luis GARCÍA GIMÉNEZ, Carlos ROMÁ MATEO, Federico V. PALLARDÓ CALATAYUD