Abstract: A printed media display system includes a media mounting surface carrying discrete male touch fastening elements arranged in a field extending across the surface, and print media in the form of a flexible sheet having a fastening side and a print side, the fastening side featuring engageable fibers in a fibrous field extending across a length and width of the flexible sheet. The system exhibits particularly good wrinkle propagation and engaged alignment properties.

Abstract: An energy dissipating link includes: an elongated base having opposite, first and second end portions; and a plurality of touch fasteners permanently coupled to the base, each of the plurality of touch fasteners releasably engageable with at least one other of the touch fasteners. The plurality of touch fasteners is arranged on the base to form first and second closures, each including engagements between respective fastening elements of two or more of the plurality of touch fasteners. The plurality of touch fasteners is configured such that: in response to a tensile load applied to the end portions of the base, the engaged touch fasteners of the first closure are loaded in shear along a shear plane; and in response to a tensile overload condition causing shear displacement of the touch fasteners of the first closure, the engaged touch fasteners of the second closure are subjected to a peel load.

Abstract: An energy dissipating link for a tether includes: an elongated base having opposite, first and second end portions; a first touch fastener permanently coupled to the base proximate the first base end portion; and a second touch fastener permanently coupled to the base proximate the second base end portion. The second touch fastener is engageable with the first touch fastener to form a releasable closure defining a shear plane. With the first and second touch fasteners engaged to transmit a tensile load between the first and second end portions, and with the engaged touch fasteners loaded in shear in the shear plane, the base includes a longitudinally slack idler section between the first and second end portions. The idler section of the base is configured to transmit tensile load upon an energy-dissipating shear disengagement of the first and second touch fasteners by a tensile overload.

Abstract: An energy dissipating link for a tether includes: an elongated base having opposite, first and second end portions; a first touch fastener permanently coupled to the base proximate the first base end portion; and a second touch fastener permanently coupled to the base proximate the second base end portion. The second touch fastener is engageable with the first touch fastener to form a releasable closure defining a shear plane. With the first and second touch fasteners engaged to transmit a tensile load between the first and second end portions, and with the engaged touch fasteners loaded in shear in the shear plane, the base includes a longitudinally slack idler section between the first and second end portions. The idler section of the base is configured to transmit tensile load upon an energy-dissipating shear disengagement of the first and second touch fasteners by a tensile overload.

Abstract: An energy dissipating link includes: an elongated base having opposite, first and second end portions; and a plurality of touch fasteners permanently coupled to the base, each of the plurality of touch fasteners releasably engageable with at least one other of the touch fasteners. The plurality of touch fasteners is arranged on the base to form first and second closures, each including engagements between respective fastening elements of two or more of the plurality of touch fasteners. The plurality of touch fasteners is configured such that: in response to a tensile load applied to the end portions of the base, the engaged touch fasteners of the first closure are loaded in shear along a shear plane; and in response to a tensile overload condition causing shear displacement of the touch fasteners of the first closure, the engaged touch fasteners of the second closure are subjected to a peel load.

Abstract: The method of generating multi-parametric nosological images including the steps of obtaining a stack of images; improving such images; reducing the images to a new space of equivalent representation; classifying in an unsupervised manner the units of the images obtained according to a pre-established number of classes without biological interpretation; automatically assigning multi-parametric profiles to the obtained classes; and generating a nosological image through the obtained classes. The system includes an imaging unit; an image processing unit for processing the obtained images and generating therefrom a multi-parametric nosological image; a connection for transmitting the images obtained by the imaging unit to the image processing unit; and a display for displaying the generated multi-parametric nosological image.

Abstract: An edge of a moisture barrier membrane, such as of a roof assembly, is attached and sealed using a moisture-impermeable sealing tape. The membrane has a fibrous surface and a non-fibrous surface. The tap is secured to a surface to which the edge of the membrane is to be attached, and positioned to underlie and extend along the edge of the membrane. The tape has a first edge width carrying a field of discrete touch fastener elements, and a second edge width carrying a layer of adhesive. The fibrous surface of the moisture barrier membrane is engaged against the field of touch fastener elements, such that the moisture barrier membrane overlaps the first edge width of the tape, and then the sealing tape is folded over the edge of the moisture barrier membrane, such that the adhesive engages the non-fibrous surface of the moisture barrier membrane.

Abstract: The present invention provides connexin hemichannel blockers for the treatment of epilepsy. In particular, the present invention relates to organic compounds which act as selective blockers connexin hemichannels which are useful in the treatment of epilepsy. In another embodiment of the present invention there is provided a composition comprising a selective connexin hemichannels blocker compounds useful in the treatment of epilepsy in combination with other antiepileptic compounds.

Abstract: The method of generating multi-parametric nosological images including the steps of obtaining a stack of images; improving such images; reducing the images to a new space of equivalent representation; classifying in an unsupervised manner the units of the images obtained according to a pre-established number of classes without biological interpretation; automatically assigning multi-parametric profiles to the obtained classes; and generating a nosological image through the obtained classes. The system includes an imaging unit; an image processing unit for processing the obtained images and generating therefrom a multi-parametric nosological image; a connection for transmitting the images obtained by the imaging unit to the image processing unit; and a display for displaying the generated multi-parametric nosological image.

Abstract: A printed media display system includes a media mounting surface carrying discrete male touch fastening elements arranged in a field extending across the surface, and print media in the form of a flexible sheet having a fastening side and a print side, the fastening side featuring engageable fibers in a fibrous field extending across a length and width of the flexible sheet. The system exhibits particularly good wrinkle propagation and engaged alignment properties.

Abstract: An edge of a moisture barrier membrane, such as of a roof assembly, is attached and sealed using a moisture-impermeable sealing tape. The membrane has a fibrous surface and a non-fibrous surface. The tap is secured to a surface to which the edge of the membrane is to be attached, and positioned to underlie and extend along the edge of the membrane. The tape has a first edge width carrying a field of discrete touch fastener elements, and a second edge width carrying a layer of adhesive. The fibrous surface of the moisture barrier membrane is engaged against the field of touch fastener elements, such that the moisture barrier membrane overlaps the first edge width of the tape, and then the sealing tape is folded over the edge of the moisture barrier membrane, such that the adhesive engages the non-fibrous surface of the moisture barrier membrane.

Abstract: The invention provides identification methods of specific modulators of hemichannels formed by connexin through the use of structural bioinformation methods for the calculation of the interaction energy with ligands and compositions to selectively modulate the activity of hemichannels formed by connexins. Among other aspects, the invention describes a computer-aided method, where estimating the interaction energy between ligands coming from a database of chemical compounds is possible, with a binding pocket defined by the region comprising the residues of 3-10 (NTH), 29-40 (TM1), 74-93 (TM2) of a protomer and residues 29-40 (TM1) of an adjacent protomer in connexin 26 or the equivalent residues in other connexins.

Abstract: Embodiments of the invention provide methods and apparatus for reducing steering effort in a vehicle. In one embodiment, a method for installing a steering-assist system onto a vehicle having an electrically powered steering system is provided. The method includes placing a controller between a torque sensor and an electronic control unit (ECU) disposed on the vehicle, coupling a primary signal line from the torque sensor to be in electrical communication with the controller, and coupling a secondary signal line to the controller to be in electrical communication with the ECU, wherein, when movement is detected by the torque sensor, the torque sensor provides a primary signal to the controller and the controller provides a secondary signal to the ECU, the secondary signal being different than the primary signal.

Abstract: Tissue orientation devices include a perforated tissue support with at least one perforated channel for receiving a tissue sample, and a plurality of tabs configured to extend along and into the channel to retain the tissue sample during processing and embedding. Tissue orientation devices include elongated legs coupled together for holding one or more biopsy tissue samples therebetween. Associated methods include using the cassettes and orientation devices to hold and orient tissue samples for processing, embedding and microtome sectioning.

Abstract: Tissue orientation devices include a perforated tissue support with at least one perforated channel for receiving a tissue sample, and a plurality of tabs configured to extend along and into the channel to retain the tissue sample during processing and embedding. Tissue orientation devices include elongated legs coupled together for holding one or more biopsy tissue samples therebetween. Associated methods include using the cassettes and orientation devices to hold and orient tissue samples for processing, embedding and microtome sectioning.

Abstract: Tissue orientation devices include a perforated tissue support with at least one perforated channel for receiving a tissue sample, and a plurality of tabs configured to extend along and into the channel to retain the tissue sample during processing and embedding. Tissue orientation devices include elongated legs coupled together for holding one or more biopsy tissue samples therebetween. Associated methods include using the cassettes and orientation devices to hold and orient tissue samples for processing, embedding and microtome sectioning.

Abstract: Embodiments of the invention provide methods and apparatus for reducing steering effort in a vehicle. In one embodiment, a method for installing a steering-assist system onto a vehicle having an electrically powered steering system is provided. The method includes placing a controller between a torque sensor and an electronic control unit (ECU) disposed on the vehicle, coupling a primary signal line from the torque sensor to be in electrical communication with the controller, and coupling a secondary signal line to the controller to be in electrical communication with the ECU, wherein, when movement is detected by the torque sensor, the torque sensor provides a primary signal to the controller and the controller provides a secondary signal to the ECU, the secondary signal being different than the primary signal.

Abstract: Tissue orientation devices include a perforated tissue support with at least one perforated channel for receiving a tissue sample, and a plurality of tabs configured to extend along and into the channel to retain the tissue sample during processing and embedding. Tissue orientation devices include elongated legs coupled together for holding one or more biopsy tissue samples therebetween. Associated methods include using the cassettes and orientation devices to hold and orient tissue samples for processing, embedding and microtome sectioning.

Abstract: A manually driven syringe for injecting fluids under high pressure is described that includes a barrel (12), a plunger (13) that is received within the barrel and extends rearwardly through an aperture (28) in the body (27) of a handle (14) which carries a pair of opposed finger grips (19, 22). The finger grips are located rearwardly of the barrel and laterally of the shaft (19) of the plunger, elongated so as to each accommodate two fingers, and angled rearwardly. This design minimizes the distance between (a) the inner edges of the grips and (b) the grips and the head of the extended plunger, thus making the syringe easier to grip in the palm of the hand and enabling the syringe to be gripped strongly between the fingers and the palm.