Abstract: Described herein is a method for predicting operons in prokaryotes. Also described herein are vectors comprising operons predicted using the this method as well as methods of using antisense nucleic acids complementary to at least a portion of a predicted proliferation-required operon to inhibit cellular proliferation. Methods of using such antisense nucleic acids to sensitize cells for use in assays to identify compounds which possess the ability to inhibit cellular proliferation are also described.

Abstract: A scroll compressor is provided with a non-circular back pressure chamber which is still concentric about a center axis of the compressor, such as the center axis of the drive shaft. Stated another way, an inner seal and an outer seal define a back pressure chamber. The two seals are concentric, but at least one of the seals is non-circular. In this way, reduced a back pressure chamber can be provided while still allowing the amount of orbital movement necessary for the tap for communicating a compressed refrigerant to the back pressure chamber.

Abstract: Low voltage electrical power is supplied to a diagnostic control device in a sealed compressor. Electrical power is tapped from a high voltage power line and transformed to low voltage power that in turn operates the diagnostic control device. The diagnostic control device and the electric voltage transforming system are housed within the sealed compressor shell, thus eliminating the need for additional openings in the compressor shell. Other low voltage devices can be powered in this way.

Abstract: The sequences of antisense nucleic acids which inhibit the proliferation of prokaryotes are disclosed. Cell-based assays which employ the antisense nucleic acids to identify and develop antibiotics are also disclosed. The antisense nucleic acids can also be used to identify proteins required for proliferation, express these proteins or portions thereof, obtain antibodies capable of specifically binding to the expressed proteins, and to use those expressed proteins as a screen to isolate candidate molecules for rational drug discovery programs. The nucleic acids can also be used to screen for homologous nucleic acids that are required for proliferation in cells other than Staphylococcus aureus, Salmonella typhimurium, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The nucleic acids of the present invention can also be used in various assay systems to screen for proliferation required genes in other organisms.

Abstract: The present invention provides C. neoformans genes that are essential and are potential targets for drug screening. The nucleotide sequence of the target genes can be used for various drug discovery purposes, such as expression of the recombinant protein, hybridization assay and construction of nucleic acid arrays. The uses of proteins encoded by the essential genes, and genetically engineered cells comprising modified alleles of essential genes in various screening methods are also encompassed by the invention. The present invention also provides methods and compositions that enable the experimental determination as to whether any gene in the genome of Cryptococcus neoformans is essential, and whether that gene is required for virulence or pathogenicity. The identification of essential genes and those genes critical to the development of virulent infections, provides a basis for the development of screens for new drugs against C. neoformans.

Abstract: Low voltage electrical power is supplied to a diagnostic control device in a sealed compressor. Electrical power is tapped from a high voltage power line and transformed to low voltage power that in turn operates the diagnostic control device. The diagnostic control device and the electric voltage transforming system are housed within the sealed compressor shell, thus eliminating the need for additional openings in the compressor shell. Other low voltage devices can be powered in this way.

Abstract: A low cost protective clutch member is positioned adjacent an end of the drive shaft in a scroll compressor. The device is a thin washer having a tab which is selectively driven against the housing stop when the compressor is driven in a forward direction, but is movable into a notch in the shaft when the shaft is driven in a reverse direction. The tab prevents rotation of the shaft when in the notch.

Abstract: A number of improvements increase the flow of lubricant within a scroll compressor. A centrifugal oil separator is mounted on the discharge port to remove oil from the refrigerant. The oil is returned through a leak path such that the oil can easily return back to a suction pressure chamber. The leak path is preferably upstream of a check valve. Thus, at shutdown, the leak path will not allow upstream components to also equalize in pressure with the suction pressure chamber of the compressor. Further, a number of embodiments include ways of resisting flow of refrigerant through the leak path, while still allowing oil flow. A number of valve elements are described which perform this function. Alternatively, labyrinth flow paths, or positioning of the return paths such that it will be closed when the compressor is shut down are disclosed.

Abstract: Low voltage electrical power is supplied to a diagnostic control device in a sealed compressor. Electrical power is tapped from a high voltage power line and transformed to low voltage power that in turn operates the diagnostic control device. The diagnostic control device and the electric voltage transforming system are housed within the sealed compressor shell, thus eliminating the need for additional openings in the compressor shell. Other low voltage devices can be powered in this way.

Abstract: The present invention provides nucleotide sequences, methods and compositions that enable the experimental determination as to whether any gene in the genome of Aspegillus fumigatus is essential, and whether that gene is required for virulence or pathogenicity. The methods involve the construction of genetic mutants in which a target gene is placed under conditional expression. The identification of essential genes and those genes critical to the development of virulent infections, provides a basis for the development of screens for new drugs against Aspergillus fumigatus.

Abstract: A system includes a motor mounted within a housing and a compressor pump unit. A single-phase PSC motor includes a switch assembly which selectively connects primary or alternate windings. During normal load operation, when maximum efficiency is desired, the switch is placed in one position, then during high load operation, when maximum torque output is needed at maximum a load point, the switch is placed in the closed position. In effect, the number of main winding turns is decreased and the motor is strengthened. As the auxiliary capacitors are also now connected in parallel, the net effect is an increase in the total auxiliary capacitance, which also serves to strengthen the motor. Another embodiment provides a switch for a three-phase WYE connected motor. In yet another embodiment, a three phase delta connected motor switch is provided.

Abstract: Low voltage electrical power is supplied to a diagnostic control device in a sealed compressor. Electrical power is tapped from a high voltage power line and transformed to low voltage power that in turn operates the diagnostic control device. The diagnostic control device and the electric voltage transforming system are housed within the sealed compressor shell, thus eliminating the need for additional openings in the compressor shell. Other low voltage devices can be powered in this way.

Abstract: A low cost protective clutch member is positioned adjacent an end of the drive shaft in a scroll compressor. The device is a thin washer having a tab which is selectively driven against the housing stop when the compressor is driven in a forward direction, but is movable into a notch in the shaft when the shaft is driven in a reverse direction. The tab prevents rotation of the shaft when in the notch.

Abstract: A variable size is provided for a discharge port in a scroll compressor. The variable size is movable dependent on conditions within the scroll compressor to achieve a desired pressure ratio based upon operational conditions in the compressor or an associated refrigerant cycle. In one embodiment a plunger moves axially to increase or decrease the size of a discharge port. In a second embodiment, the plunger rotates about an axis and has a groove that is selectively aligned with the port to increase or decrease the effective size of the port.

Abstract: A compressor diagnostic system incorporates a control which receives a plurality of data streams about various operational features of the compressor. As an example, both temperature and pressure of the suction and discharge refrigerant are taken and sent to the control. Moreover, information with regard to the power being supplied to the motor is taken and stored. All of this information is utilized at a control which compares the information to expected values and determines a fault based upon the evaluation. Moreover, in another feature of this invention, much of this data is stored, and maintained at the compressor. In the event of a compressor failure, this stored information will provide a maintenance worker with a good indication of why the compressor failed.

Abstract: A system includes a motor mounted within a housing and a compressor pump unit. A single-phase PSC motor includes a switch assembly which selectively connects primary or alternate windings. During normal load operation, when maximum efficiency is desired, the switch is placed in one position, then during high load operation, when maximum torque output is needed at maximum a load point, the switch is placed in the closed position. In effect, the number of main winding turns is decreased and the motor is strengthened. As the auxiliary capacitors are also now connected in parallel, the net effect is an increase in the total auxiliary capacitance, which also serves to strengthen the motor. Another embodiment provides a switch for a three-phase WYE connected motor. In yet another embodiment, a three phase delta connected motor switch is provided.

Abstract: An unloader valve for a scroll compressor to selectively communicate suction and discharge is positioned outwardly of the compressor housing. In this way, the unloader valve is ideally positioned to address several system failures. As an example, loss or charge, reverse running, fan failure, etc. are all addressed in an efficient and quick manner. The unloader valve may be the normal unloader valve controlled by a system control which also selectively controls capacity. The unloader valve control is modified such that it is also operable to open the unloader valve when a system failure is detected.

Abstract: An improved scroll compressor having an axially movable non-orbiting scroll eliminates the need for a separator plate. With the elimination of the separator plate, a back pressure chamber is provided to resist the discharge pressure which will be directed against a rear face of the non-orbiting scroll. In other embodiments, a seal on the rear of the non-orbiting scroll contacts the inner periphery of the end cap. Various ways of increasing the discharge pressure volume, or eliminating undesirable noise are also disclosed. Further, several ways of connecting the end cap to the center shell are also disclosed.

Abstract: A scroll compressor is provided that has greater control over the compressed volume by having a plurality of sequentially spaced unloader valves and associated holes. By providing the plurality of valves, a control achieves greater variation over the final compressed volume. The present invention is most preferably utilized in the type of scroll compressor having a hybrid wrap geometry to provide an increased volume of refrigerant adjacent the suction area of the compressor.

Abstract: A compressor diagnostic system incorporates a control which receives a plurality of data streams about various operational features of the compressor. As an example, both temperature and pressure of the suction and discharge refrigerant are taken and sent to the control. Moreover, information with regard to the power being supplied to the motor is taken and stored. All of this information is utilized at a control which compares the information to expected values and determines a fault based upon the evaluation. Moreover, in another feature of this invention, much of this data is stored, and maintained at the compressor. In the event of a compressor failure, this stored information will provide a maintenance worker with a good indication of why the compressor failed.