Abstract: An apparatus for use in a minimally invasive prostate cancer detection system, using a fluorophore peptide dye conjugate compound which has at least one absorption wavelength in a range of 380 to 1400 nm, wherein said compound attaches to a prostate-specific membrane antigen (PSMA) expressed by a prostate cancer cell. A photo-acoustic imaging probe to be inserted in at least one of a rectum, urethra, or placed proximal the prostate. The probe having an emitter to emit a first signal at the prostrate and a prostate cancer, excite the conjugate compound and a receiver to receive a second signal from said conjugate compound, thereby indicating a cancerous region of the prostrate. A processor unit connected to said probe, is configured and operable for receiving and processing said to produce a tomographic representation of the prostrate.

Abstract: A fire detector is disclosed that successively images a particular area from geosynchronous Earth orbit satellite to attain very good signal-to-noise ratios against Poisson fluctuations within one second. Differences between such images allow for the automatic detection of small fires greater than 12 square meters. Imaging typically takes place in transparent bands of the infrared spectrum, thereby rendering smoke from the fire and light clouds somewhat transparent. Several algorithms are disclosed that can help reduce false fire alarms, and their efficiencies are shown. Early fire detection and response would be of great value in the United States and other nations, as wild land fires destroy property and lives and contribute around five percent of the US global carbon dioxide contribution. Such apparatus would incorporate modern imaging detectors, software, and algorithms able to detect heat from early and small fires, and yield detection times on a scale of minutes.

Abstract: A fire detector is disclosed that successively images a particular area from geosynchronous Earth orbit satellite to attain very good signal-to-noise ratios against Poisson fluctuations within one second. Differences between such images allow for the automatic detection of small fires greater than 12 square meters. Imaging typically takes place in transparent bands of the infrared spectrum, thereby rendering smoke from the fire and light clouds somewhat transparent. Several algorithms are disclosed that can help reduce false fire alarms, and their efficiencies are shown. Early fire detection and response would be of great value in the United States and other nations, as wild land fires destroy property and lives and contribute around five percent of the US global carbon dioxide contribution. Such apparatus would incorporate modern imaging detectors, software, and algorithms able to detect heat from early and small fires, and yield detection times on a scale of minutes.

Abstract: Apparatus for helmeting with carotid collars works in conjunction with a transcranial Doppler, phased array photoacoustic device to transmit a first energy to a region of interest at an internal site of a subject to produce an image and blood flow velocities of a region of interest by outputting an optical excitation energy to said region of interest and heating said region, causing a transient thermoelastic expansion and produce a wideband ultrasonic emission. Systems integrate and register the signals for use in, for example, acute stroke care.