Patents by Inventor Carmen A. Puliafito
Carmen A. Puliafito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8319974Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: GrantFiled: March 8, 2011Date of Patent: November 27, 2012Assignee: Carl Zeiss Meditec, Inc.Inventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Publication number: 20110273667Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: ApplicationFiled: March 8, 2011Publication date: November 10, 2011Applicant: University of MiamiInventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Patent number: 7924429Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: GrantFiled: December 22, 2009Date of Patent: April 12, 2011Assignee: University of MiamiInventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Publication number: 20100208201Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: ApplicationFiled: December 22, 2009Publication date: August 19, 2010Applicant: University of MiamiInventors: Robert W. KNIGHTON, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Patent number: 7659990Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: GrantFiled: February 4, 2009Date of Patent: February 9, 2010Assignee: University of MiamiInventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Publication number: 20090180123Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: ApplicationFiled: February 4, 2009Publication date: July 16, 2009Inventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Patent number: 7505142Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: GrantFiled: October 18, 2007Date of Patent: March 17, 2009Assignee: University of MiamiInventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Publication number: 20080068560Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: ApplicationFiled: October 18, 2007Publication date: March 20, 2008Inventors: Robert Knighton, Shuliang Jiao, Giovanni Gregori, Carmen Puliafito
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Patent number: 7301644Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: GrantFiled: September 6, 2005Date of Patent: November 27, 2007Assignee: University of MiamiInventors: Robert W. Knighton, Shuliang Jiao, Giovanni Gregori, Carmen A. Puliafito
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Publication number: 20060119858Abstract: A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies.Type: ApplicationFiled: September 6, 2005Publication date: June 8, 2006Inventors: Robert Knighton, Shuliang Jiao, Giovanni Gregori, Carmen Puliafito
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Publication number: 20060100527Abstract: A system, method and apparatus for speckle noise removal based upon structural correlation in an OCT imaging system. In accordance with the present invention, several two- or three-dimensional OCT image scans can be acquired for processing by an adaptive algorithm. Specifically, at each image point an image intensity can be computed that quantifies a measure of dispersion of the image values in a particular direction with respect to their mean. Subsequently, a direction ?0(x, y) can be selected which minimizes the energy function at the given pixel (x, y). Finally, a value proportional to a local average of the input image around the point (x, y) can be chosen for the output image. In this way speckle noise can be minimized if not removed while, at the same time, maintaining the image substantially free of obvious artifacts.Type: ApplicationFiled: October 5, 2005Publication date: May 11, 2006Inventors: Giovanni Gregori, Carmen Puliafito, Robert Knighton
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Patent number: 5459570Abstract: A method and apparatus for performing various optical measurements is provided utilizing an optical coherence domain refrectometer (OCDR). A short coherence optical radiation source applies optical radiation through like optical paths to a sample and an optical reflector. The optical reflector is movable in accordance with a predetermined velocity profile to permit interferometric scanning of the sample, the resulting output having a Doppler shift frequency modulation. This output may be demodulated and detected to obtain desired measurements and other information. Additional information may be obtained by applying radiation from two or more sources at different wavelengths to the sample and reflector and by separately demodulating the resulting outputs before processing.Type: GrantFiled: March 16, 1993Date of Patent: October 17, 1995Assignee: Massachusetts Institute of TechnologyInventors: Eric A. Swanson, David Huang, James G. Fujimoto, Carmen A. Puliafito, Charles P. Lin, Joseph S. Schuman
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Patent number: 5321501Abstract: A method and apparatus for performing optical imaging on a sample wherein longitudinal scanning or positioning in the sample is provided by either varying relative optical path lengths for an optical path leading to the sample and to a reference reflector, or by varying an optical characteristic of the output from an optical source applied to the apparatus. Transverse scanning in one or two dimensions is provided on the sample by providing controlled relative movement between the sample and a probe module in such direction and/or by steering optical radiation in the probe module to a selected transverse position. The probe module may be an external module or may be an endoscope or angioscope utilized for scanning internal channels. Multiple optical paths may be provided for parallel scanning and focus may be enhanced by varying the focal point in the sample in synchronism with longitudinal scanning of the sample.Type: GrantFiled: April 29, 1992Date of Patent: June 14, 1994Assignee: Massachusetts Institute of TechnologyInventors: Eric A. Swanson, David Huang, James G. Fujimoto, Carmen A. Puliafito, Charles P. Lin, Joel S. Schuman
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Patent number: 4597649Abstract: A slit lamp with surgical laser capability includes an x-y table. An optical micrometer, readily retrofittable onto existing slit lamps, is mounted on the x-y table to measure table displacement in the y direction. The measuring electronics are resettable to allow the operator to select any y position from which the displacement is to be algebraically measured. Compact display optics are retrofittably mounted on the ocular assembly of the slit lamp between the collimator and the eyepiece to insert a reduced image of an LED indicator displaying the measured data into the periphery of the ophthalmic image seen through the eyepiece. An LCD indicator displaying the same data is mounted on the x-y table to allow positioning of the table without looking into the eyepiece. The LED indicator lends itself to display of laser operational data in addition to positional data.Type: GrantFiled: October 28, 1983Date of Patent: July 1, 1986Assignee: American Hospital Supply CorporationInventors: James R. Swaniger, Roger F. Steinert, Carmen A. Puliafito