Patents by Inventor Carmen Bano

Carmen Bano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ionically cross-linked polymeric microcapsules
    Patent number: 5494682
    Abstract: A method for encapsulating biologically-labile materials such as proteins, liposomes, bacteria and eucaryotic cells within a synthetic polymeric capsule, and the product thereof, are disclosed. The method is based on the use of a water-soluble polymer with charged side chains that are crosslinked with multivalent ions of the opposite charge to form a gel encapsulating biological material, that is optionally further stabilized by interactions with multivalent polyions of the same charge as those used to form the gel. In the preferred embodiment, hydrolytically stable polyphosphazenes are formed of monomers having carboxylic acid side groups that are crosslinked by divalent or trivalent cations such as Ca.sup.2+ or Al.sup.3+, then stabilized with a polycation such as poly-L-lysine. A variety of different compositions can be formed from the crosslinked polymer.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: February 27, 1996
    Assignees: Massachusetts Institute of Technology, The Penn State Research Foundation
    Inventors: Smadar Cohen, Carmen Bano, Karyn B. Visscher, Marie Chow, Harry R. Allcock, Robert S. Langer
  • Ionically cross-linked polymeric microcapsules
    Patent number: 5308701
    Abstract: A method for encapsulating biologically-labile materials such as proteins, liposomes, bacteria and eucaryotic cells within a synthetic polymeric capsule, and the product thereof, are disclosed. The method is based on the use of a water-soluble polymer with charged side chains that are crosslinked with multivalent ions of the opposite charge to form a gel encapsulating biological material, that is optionally further stabilized by interactions with multivalent polyions of the same charge as those used to form the gel. In the preferred embodiment, hydrolytically stable polyphosphazenes are formed of monomers having carboxylic acid side groups that are crosslinked by divalent or trivalent cations such as Ca.sup.2+ or Al.sup.3+, then stabilized with a polycation such as poly-L-lysine. A variety of different compositions can be formed from the crosslinked polymer.
    Type: Grant
    Filed: May 8, 1992
    Date of Patent: May 3, 1994
    Inventors: Smadar Cohen, Carmen Bano, Karyn B. Visscher, Marie B. Chow, Harry R. Allcock, Robert S. Langer
  • Ionically cross-linked polymeric microcapsules
    Patent number: 5149543
    Abstract: A method for encapsulating biologically-labile materials such as proteins, liposomes, bacteria and eucaryotic cells within a synthetic polymeric capsule, and the product thereof, are disclosed. The method is based on the use of a water-soluble polymer with charged side chains that are crosslinked with multivalent ions of the opposite charge to form a gel encapsulating biological material, that is optionally further stabilized by interactions with multivalent polyions of the same charge as those used to form the gel. In the preferred embodiment, hydrolytically stable polyphosphazenes are formed of monomers having carboxylic acid side groups that are crosslinked by divalent or trivalent cations such as Ca.sup.2+ or Al.sup.3+, then stabilized with a polycation such as poly-L-lysine. A variety of different compositions can be formed from the crosslinked polymer.
    Type: Grant
    Filed: October 5, 1990
    Date of Patent: September 22, 1992
    Assignees: Massachusetts Institute of Technology, Pennsylvania Research Corporation
    Inventors: Smadar Cohen, Carmen Bano, Karyn B. Visscher, Marie Chow, Harry R. Allcock, Robert S. Langer