Patents by Inventor Carmen Schleissner Sanchez

Carmen Schleissner Sanchez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTICANCER COMPOUNDS
    Publication number: 20210317490
    Abstract: Anticancer compounds of general formula I wherein R1 to R4 take various meanings, for use in the treatment of cancer. A novel Labrenzia sp. strain named PHM005 with Accession Deposit Number CECT-9225, a method of producing compounds of the invention and analogues thereof by using the PHM005 strain and the Lab gene cluster codifying the biosynthesis of pederin-like and onnamide-like compounds are also provided.
    Type: Application
    Filed: March 16, 2018
    Publication date: October 14, 2021
    Inventors: Librada María CAÑEDO HERNÁNDEZ, Fernando DE LA CALLE VERDÚ, María Pilar RODRÍGUEZ RAMOS, María del Carmen SCHLEISSNER SÁNCHEZ, Paz ZÚÑIGA GIRÓN
  • Gene cluster involved in safracin biosynthesis and its uses for genetic engineering
    Patent number: 7723068
    Abstract: A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ ID NO:1, variants or portions thereof, or at least one of the sacA, sacB, sacC, sacC, sacD, sacE, sacF, sacG, sacH, sacH, saI, sacJ, orf1, orf2, orf3 or orf4 genes, including variants or portions.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: May 25, 2010
    Assignee: PharmaMar, S.A.
    Inventors: Ana Velasco Iglesias, Fernando de la Calle, Tomás Aparicio Pérez, Carmen Schleissner Sánchez, Paloma Acebo Páis, Pilar Rodríguez Ramos, Fernando Reyes Benítez, Rubén Henrìquez Peláez
  • Genes Involved in the Biosynthesis of Thiocoraline and Heterologous Production of Same
    Publication number: 20090130675
    Abstract: The invention relates to genes involved in the biosynthesis of thiocoraline and to the heterologous production of same. According to the invention, the cluster of genes responsible for the biosynthesis of thiocoraline was identified and cloned. Said cluster of genes can be used in the heterologous production of thiocoraline which has an antitumor and antibacterial activity.
    Type: Application
    Filed: August 1, 2006
    Publication date: May 21, 2009
    Applicant: PHARMA MAR, S.A.
    Inventors: Angelina Ramos Castro, Alfredo Fernandez Brana, Felipe Lombo Brugos, Carmen Mendez Fernandez, Jose Antonio Salas Fernandez, Ana Velasco Iglesias, Carmen Schleissner Sanchez
  • The Gene Cluster Involved in Safracin Biosynthesis and Its Uses for Genetic Engineering
    Publication number: 20080182302
    Abstract: A gene cluster has open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule.
    Type: Application
    Filed: September 22, 2005
    Publication date: July 31, 2008
    Applicant: Pharma Mar, S.A.
    Inventors: Ana Velasco Iglesias, Fernando de la Calle, Tomás Aparicio Pérez, Carmen Schleissner Sánchez, Paloma Acebo Páis, Pilar Rodriguez Ramos, Fernando Reyes Benitez, Ruben Henriquez Pelaez
  • Gene cluster involved in safracin biosynthesis and its uses for genetic engineering
    Publication number: 20060134764
    Abstract: A gene cluster has open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule.
    Type: Application
    Filed: December 19, 2003
    Publication date: June 22, 2006
    Inventors: Ana Velasco Iglesias, Fernando De La Calle, Tomas Aparicio Perez, Carmen Schleissner Sanchez, Paloma Acebo Pais, Pilar Rodriguez Ramos, Fernando Reyes Benitez, Ruben Henriquez Pelaez
  • Method of production of astaxanthin by fermenting selected strains of xanthophyllomyces dendrorhous
    Publication number: 20050124032
    Abstract: The present invention describes methods for (i) obtaining astaxanthin-overproducing strains of X. dendrorhous and (ii) the use of the aforementioned strains in improved conditions of fermentation. The methods used for selecting the strains are based on: (i) resistance to inhibitors of steroid synthesis, to inhibitors of respiration and to compounds that induce the formation of free radicals, (ii) color intensity of the colony and production of carotenoids on solid medium, (iii) production of astaxanthin in darkness, (iv) production of astaxanthin in conditions with a raised temperature and (v) production of astaxanthin with carbon sources other than glucose. These methods permit the efficient selection of mutants of X. dendrorhous with astaxanthin yields higher than the parent strain and little accumulation of other carotenoids. Cultivation of X. dendrorhous in liquid medium makes it possible to obtain a biomass that can be used directly in human and animal nutrition.
    Type: Application
    Filed: February 3, 2003
    Publication date: June 9, 2005
    Inventors: Juan De La Fuente Moreno, Enrique Peiro Cezon, Bruno Diez Garcia, Ana Marcos Rodriguez, Carmen Schleissner Sanchez, Marta Rodriguez Saiz, Carmelita Rodriguez Otero, Walter Cabri, Jose Barredo Fuente
  • Process for increasing the production of penicillin G (benzylpenicillin) in Penicillium chrysogenum by expression of the PCL gene
    Patent number: 6251655
    Abstract: An isolated DNA encoding phenyl acetyl-CoA-ligase and a process of increasing the production of penicillin G in a strain of Penicillium chrysogenum by transforming the strain with the isolated DNA. Also vectors and host organisms having the isolated DNA.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: June 26, 2001
    Assignee: Antibioticos S.A.
    Inventors: Baltasar Minambres Rodriguez, Honorina Martinez Blanco, Elias Rodriguez Olivera, Belen Garcia Alonso, Jose Manuel Fernandez Canon, Jose Luis Barredo Fuente, Bruno Diez Garcia, Carmen Schleissner Sanchez, Miguel Angel Moreno Valle, Francisco Salto Maldonado, Jose Maria Luengo Rodriguez
  • Process for producing the enzyme D-amino acid oxidase of Rhodotorula gracilis in host cells
    Patent number: 6187574
    Abstract: Process for producing the enzyme D-amino acid oxydase of Rhodotorula gracilis in host cells. The process for the expression of the enzyme comprises isolating the complementary DNA corresponding to the messager RNA of the gene which codes for the D-amino acid oxydase of any strain of Rhodotorula gracillis producing said enzyme; fusing the fragment of DNA which codes for D-amino acid oxydase of Rhodotorula gracillis with a DNA sequence which contains a site of union to the ribosome and a high efficiency promoter sequence for the express of genes in host cells; inserting the DNA fragment into a plasmid appropriate for the host cell; cultivating the host cells transformed with said plasmid; and collecting the enzyme.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: February 13, 2001
    Assignee: Antibiotics, S.A.
    Inventors: Jose Luis Garcia Lopez, Estrella Cortes Rubio, Jorge Alonso Palacios, Jose Luis Barredo Fuente, Bruno Diez Garcia, Miguel Angel Moreno Valle, Carmen Schleissner Sanchez, Alfonso Collados de la Vieja, Alejandro Vitaller Alba, Francisco Salto Maldonado