Patents by Inventor Carmen Varela Busto

Carmen Varela Busto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical entities
    Patent number: 9453031
    Abstract: Provided are chemical entities selected from compounds of formula (I), wherein R1, R2 and m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further provided are pharmaceutical compositions of the chemical entities, combination products containing the chemical entities, the use of the compositions as therapeutic agents, and methods of treatment using these compositions.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 27, 2016
    Assignee: Fundación Centro Nacional de Investigaciones Oncológicas Carlos III
    Inventors: Joaquín Pastor Fernández, Oscar Fernández-Capetillo Ruiz, Sonia Martínez González, Carmen Blanco Aparicio, María del Rosario Rico Ferreira, Luis Ignacio Toledo Lázaro, Sonsoles Rodríguez Arísteguí, Matilde Murga Costa, Carmen Varela Busto, Andrés Joaquín Lopez Contreras, Oliver Renner, María Nieto Soler, David Alvaro Cebrián Muñoz
  • CHEMICAL ENTITIES
    Publication number: 20160024112
    Abstract: Provided are chemical entities selected from compounds of formula (I), wherein R1, R2 and m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further provided are pharmaceutical compositions of the chemical entities, combination products containing the chemical entities, the use of the compositions as therapeutic agents, and methods of treatment using these compositions.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Inventors: Joaquín Pastor Fernández, Oscar Fernández-Capetillo Ruiz, Sonia Martínez González, Carmen Blanco Aparicio, María del Rosario Rico Ferreira, Luis Ignacio Toledo Lázaro, Sonsoles Rodríguez Arísteguí, Matilde Murga Costa, Carmen Varela Busto, Andrés Joaquín Lopez Contreras, Oliver Renner, María Nieto Soler, David Alvaro Cebrián Muñoz
  • Fused Imidazo [3,2 - D] Pyrazines as P13 Kinase Inhibitors
    Publication number: 20130029967
    Abstract: There is provided compounds of formula (I), wherein A1, A2, A3, A4, n, the dotted lines, B1, B1a, B2, B2a, B3, B3a, B4, B4a, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
    Type: Application
    Filed: September 24, 2010
    Publication date: January 31, 2013
    Applicant: Centro Nacional de Investigaciones Oncologicas (CNIO)
    Inventors: Joaquin Pastor Fernández, Sonia Martinez Gonzalez, Rosa Maria Alvarez Escobar, Sonsoles Rodriguez Aristegui, Esther Gonzales Cantalapiedra, Ana Isabel Hernandez Higueras, Carmen Varela Busto