Patents by Inventor Carol Ann Kreader

Carol Ann Kreader has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090240044
    Abstract: The present invention provides methods for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography.
    Type: Application
    Filed: April 1, 2009
    Publication date: September 24, 2009
    Applicant: Sigma-Aldrich Company
    Inventors: Kevin Bernard Ray, Carol Ann Kreader, Fuqiang Chen, David Eric Cutter
  • Patent number: 7531308
    Abstract: The present invention provides methods for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: May 12, 2009
    Assignee: Sigma-Aldrich Co.
    Inventors: Kevin Bernard Ray, Carol Ann Kreader, Fuqiang Chen, David Eric Cutter
  • Patent number: 6699986
    Abstract: The present invention relates to methods for separating nucleic acids from other cellular debris, especially substances that carry a net positive charge at low pH, by electrophoresis under acid conditions. In the purification method of the present invention, nucleic acids are separated from proteins found in the same biological sample by applying the sample to an electrophesis gel and subjecting the sample to electrophoresis under acid conditions to separate the nucleic acids from the proteins. The optimum pH may differ for different sample types but can be readily determined by those skilled in the art. Preferably, the separation is performed at a pH of about 2 to about 4. More preferably, electrophoresis is carried out at a pH of 2.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: March 2, 2004
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventors: Carol Ann Kreader, John Wesley Backus