Patents by Inventor Carol Ann Morris
Carol Ann Morris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150366311Abstract: A sealed contact lens package contains a sterile, unworn contact lens and a contact lens packaging solution comprising epsilon polylysine (?PLL). The ?PLL protects the contact lens from microbial contamination caused by handling the lens when it is removed from its package.Type: ApplicationFiled: May 22, 2015Publication date: December 24, 2015Applicant: CooperVision International Holding Company, LPInventors: Inna Maltseva, Carol Ann Morris, Kathleen Khong, Andrew Luk
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Patent number: 9050050Abstract: The invention provides methods and kits for monitoring the status of women's health, including HRT monitoring and determination or diagnosis of ovulation, contraception, pregnancy, menopause, polycystic ovarian disease, and female sexual dysfunction. The method comprises the steps of: (a) collecting a tear fluid from a female human; (b) determining the tear concentration of at least one hormone of relevance to female fertility, sexual differentiation or sexual dysfunction in a female human, wherein the tear concentration is diagnostics of the status of women's health.Type: GrantFiled: April 17, 2007Date of Patent: June 9, 2015Assignee: Novartis AGInventors: Fiona Patricia Carney, Carol Ann Morris
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Publication number: 20140178327Abstract: Antimicrobial ophthalmic devices such as contact lenses, ocular inserts, ocular bandages, and intraocular lenses comprise a hydrogel and an antimicrobially-effective amount of epsilon polylysine non-covalently attached to the hydrogel.Type: ApplicationFiled: December 18, 2013Publication date: June 26, 2014Applicant: CooperVision International Holding Company, LPInventors: Carol Ann Morris, Andrew Luk, Inna Maltseva, Arthur Back, Victoria Rogers, Kathleen Khong, Yun Zhang, Ying Ye, Peter Zhu
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Patent number: 8172395Abstract: The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial LbL coating containing one or more antimicrobial pepetides. The antimicrobial coating of the invention can impart to the medical an increased surface hydrophilicity and a relatively high antimicrobial activity coupled with low cytotoxicity. The antimicrobial coating of the invention has a minimal adverse effects on the desirable bulk properties of a contact lens, such as oxygen permeability, ion permeability, and optical properties. An antimicrobial coating of the present invention may find particular use in extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial LbL coating thereon.Type: GrantFiled: November 25, 2003Date of Patent: May 8, 2012Assignee: Novartis AGInventors: Fiona Patricia Carney, Manal M. Gabriel, Carol Ann Morris, John Martin Lally
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Patent number: 7666461Abstract: The present invention provides a method for forming on a medical device, preferably an ophthalmic lens, more preferably a contact lens, a diffusion-controllable coating capable of controlling the out-diffusion or release of guest materials from the medical device. The method of the invention comprises: (1) applying one layer of clay and optionally one or more layers of polyionic materials onto the medical device; or (2) applying alternatively a layer of a first polyionic material and a layer of a second polyionic material having charges opposite of the charges of the first polyionic material onto the medical device and releasing the coated medical device into a releasing medium having a composition capable of imparting a desired permeability to the diffusion-controllable coating on the medical device.Type: GrantFiled: October 20, 2004Date of Patent: February 23, 2010Assignee: Novartis AGInventors: Yongxing Qiu, Fiona Patricia Carney, Nichola Kotov, John Martin Lally, Carol Ann Morris
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Publication number: 20080260804Abstract: The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.Type: ApplicationFiled: June 18, 2008Publication date: October 23, 2008Inventors: Carol Ann Morris, Manal M. Gabriel, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Marcia Kay Ash, Fiona Patricia Carney, Courtney Flem Morgan
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Patent number: 7429462Abstract: The invention provides an in vivo screening assay and an in vitro screening assay for rapid screening of diabetes. A method of the invention includes determining a first glucose concentration in an ocular fluid of a patient; administering orally a load of carbohydrate to the patient; determining a second glucose concentration in an ocular fluid of the patient at a period of time of less than 50 minutes after orally administering of the load of carbohydrate; comparing the second glucose concentration with the first glucose concentration to determine if the patient is likely to be a diabetic. The method of the invention is performed by using a kit of the invention. The kit comprises: (1) a glucose-sensing ophthalmic device and instructions for using the glucose-sensing ophthalmic device to screen for diabetes; or (2) two or more tear-collecting devices, and a testing agent composition which specifically reacts with glucose to form a detectable signal.Type: GrantFiled: February 15, 2007Date of Patent: September 30, 2008Assignee: Novartis AGInventors: Carol Ann Morris, Fiona Patricia Carney, Jennifer Dawn Lane
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Patent number: 7402318Abstract: The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.Type: GrantFiled: November 4, 2002Date of Patent: July 22, 2008Assignee: Novartis AGInventors: Carol Ann Morris, Manal M. Gabriel, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Marcia Kay Ash, Fiona Patricia Carney, Courtney Flem Morgan
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Publication number: 20080139963Abstract: The present invention provides a contact lens, preferably a daily disposable contact lens, which can be used to collect one or more analytes of interest in a tear fluid, and in turn, determine the physiological state or health of an individual.Type: ApplicationFiled: January 10, 2008Publication date: June 12, 2008Inventors: Fiona Patricia Carney, Carol Ann Morris, Yongxing Qiu
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Patent number: 7244394Abstract: The invention, in one aspect, provides a strip for tear collection. The strip has a first end and an opposite second end and preferably has substantially uniform cross-sections from the first end to the second end. The strip is made of a hydrogel material in substantially dry state. The strip is characterized by having a substantially uniform swelling along the hydrogel strip from the first end to the second end when fully wicked by a tear fluid and by having a correlation between the volume of tear uptake by said strip and the length of the wicked end portion of said strip. A strip of the invention is useful for assay of an analyte of interest in a tear fluid. The invention also provides a method and kits for assaying an analyte of interest (e.g., lactoferrin, glucose, herpes simplex virus, hormones, etc.).Type: GrantFiled: September 3, 2003Date of Patent: July 17, 2007Assignee: Novartis AGInventors: Fiona Patricia Carney, Jennifer Dawn Lane, Carol Ann Morris
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Patent number: 6827966Abstract: The present invention provides a method for forming on a medical device, preferably an ophthalmic lens, more preferably a contact lens, a diffusion-controllable coating capable of controlling the out-diffusion or release of guest materials from the medical device. The method of the invention comprises: (1) applying one layer of clay and optionally one or more layers of polyionic materials onto the medical device; or (2) applying alternatively a layer of a first polyionic material and a layer of a second polyionic material having charges opposite of the charges of the first polyionic material onto the medical device and releasing the coated medical device into a releasing medium having a composition capable of imparting a desired permeability to the diffusion-controllable coating on the medical device.Type: GrantFiled: May 22, 2002Date of Patent: December 7, 2004Assignee: Novartis AGInventors: Yongxing Qiu, Fiona Patricia Carney, Nichola Kotov, John Martin Lally, Carol Ann Morris, Lynn Cook Winterton
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Publication number: 20040181167Abstract: The invention provides methods and kits for monitoring the status of women's health, including HRT monitoring and determination or diagnosis of ovulation, contraception, pregnancy, menopause, polycystic ovarian disease, and female sexual dysfunction. The method comprises the steps of: (a) collecting a tear fluid from a female human; (b) determining the tear concentration of at least one hormone of relevance to female fertility, sexual differentiation or sexual dysfunction in a female human, wherein the tear concentration is diagnostics of the status of women's health.Type: ApplicationFiled: March 10, 2004Publication date: September 16, 2004Inventors: Fiona Patricia Carney, Carol Ann Morris
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Publication number: 20040181172Abstract: The present invention provides a contact lens, preferably a daily disposable contact lens, which can be used to collect one or more analytes of interest in a tear fluid, and in turn, determine the physiological state or health of an individual.Type: ApplicationFiled: March 10, 2004Publication date: September 16, 2004Inventors: Fiona Patricia Carney, Carol Ann Morris, Yongxing Qiu
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Publication number: 20040135967Abstract: The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial LbL coating containing one or more antimicrobial pepetides. The antimicrobial coating of the invention can impart to the medical an increased surface hydrophilicity and a relatively high antimicrobial activity coupled with low cytotoxicity. The antimicrobial coating of the invention has a minimal adverse effects on the desirable bulk properties of a contact lens, such as oxygen permeability, ion permeability, and optical properties. An antimicrobial coating of the present invention may find particular use in extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial LbL coating thereon.Type: ApplicationFiled: November 25, 2003Publication date: July 15, 2004Inventors: Fiona Patricia Carney, Manal M. Gabriel, Carol Ann Morris, John Martin Lally
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Publication number: 20040076547Abstract: The invention, in one aspect, provides a strip for tear collection. The strip has a first end and an opposite second end and preferably has substantially uniform cross-sections from the first end to the second end. The strip is made of a hydrogel material in substantially dry state. The strip is characterized by having a substantially uniform swelling along the hydrogel strip from the first end to the second end when fully wicked by a tear fluid and by having a correlation between the volume of tear uptake by said strip and the length of the wicked end portion of said strip. A strip of the invention is useful for assay of an analyte of interest in a tear fluid. The invention also provides a method and kits for assaying an analyte of interest (e.g., lactoferrin, glucose, herpes simplex virus, hormones, etc.).Type: ApplicationFiled: September 3, 2003Publication date: April 22, 2004Inventors: Fiona Patricia Carney, Jennifer Dawn Lane, Carol Ann Morris
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Publication number: 20030117579Abstract: The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.Type: ApplicationFiled: November 4, 2002Publication date: June 26, 2003Inventors: Carol Ann Morris, Manal M. Gabriel, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Marcia Kay Ash, Fiona Patricia Carney, Courtney Flem Morgan
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Publication number: 20030039742Abstract: The present invention provides a method for forming on a medical device, preferably an ophthalmic lens, more preferably a contact lens, a diffusion-controllable coating capable of controlling the out-diffusion or release of guest materials from the medical device. The method of the invention comprises: (1) applying one layer of clay and optionally one or more layers of polyionic materials onto the medical device; or (2) applying alternatively a layer of a first polyionic material and a layer of a second polyionic material having charges opposite of the charges of the first polyionic material onto the medical device and releasing the coated medical device into a releasing medium having a composition capable of imparting a desired permeability to the diffusion-controllable coating on the medical device.Type: ApplicationFiled: May 22, 2002Publication date: February 27, 2003Inventors: Yongxing Qiu, Fiona Patricia Carney, Nichola Kotov, John Martin Lally, Carol Ann Morris, Lynn Cook Winterton