Patents by Inventor Carol Basbaum

Carol Basbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF CANCER
    Publication number: 20130331457
    Abstract: Methods of treating bladder cancer are disclosed. The methods include administering to a patient a therapeutically effective amount of a 4-iodo-3-nitrobenzamide or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 29, 2012
    Publication date: December 12, 2013
    Applicant: BIPAR SCIENCES, INC.
    Inventors: Ernest KUN, Jerome MENDELEYEV, Carol BASBAUM, Hassan LEMJABBAR-ALAOUI, Valeria S. OSSOVSKAYA
  • Treatment of Cancer
    Publication number: 20080319054
    Abstract: The present invention provides compositions of matter, kits and methods for their use in the treatment of cancer. In particular, the invention provides compositions and methods for treating cancer in a subject by inhibiting a poly-ADP-ribose polymerase, as well as providing formulations and modes of administering such compositions.
    Type: Application
    Filed: June 30, 2008
    Publication date: December 25, 2008
    Inventors: Ernest Kun, Jerome Mendeleyev, Carol Basbaum, Hassan Lemjabbar-Alaoui, Valeria Ossovskaya
  • Composition and method for treating the over-production of mucin in diseases such as otitis media using an inhibitor of MUC5AC
    Publication number: 20020151491
    Abstract: Disclosed herein is a method for the identification of a treatment for overproduction of mucin during otitis media (OM) and chronic obstructive pulmonary disease (COPD). The method uses a MUC5AC plasmid to identify novel cytoplasmic proteins of Nontypeable Haemophilus influenzae, a common mediator of OM and COPD, which up-regulate human MUC5AC mucin transcription via a positive p38 MAP kinase pathway and a negative PI 3-Kinase-Akt pathway. These proteins can be used to identify or design inhibitors of the p38 MAP kinase pathway and activators of the PI 3-kinase Akt pathway.
    Type: Application
    Filed: November 27, 2001
    Publication date: October 17, 2002
    Inventors: Jian-Dong Li, David Lim, Haidong Xu, Beinan Wang, Tsuyoshi Shuto, Carol Basbaum, Young S. Kim
  • Compositions and methods for the inhibition of MUC-5 mucin gene expression
    Patent number: 6440672
    Abstract: The invention relates to methods for identifying inhibitors of mucin production, methods for inhibiting mucin production and methods for treating airway diseases, such as cystic fibrosis, chronic bronchitis, bronchial pneumonia and asthma. Compositions are provided for use in the method comprising reporter gene constructs which are inducible by mucomones.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: August 27, 2002
    Assignee: The Regents of the University of California
    Inventors: Carol Basbaum, Marianne Gallup, Daizong Li, Assefa Gebremichael, Erin Gensch
  • Compositions and methods for the inhibition of MUC-5 mucin gene expression
    Patent number: 6136539
    Abstract: The invention relates to methods for identifying inhibitors of mucin production, methods for inhibiting mucin production and methods for treating airway diseases, such as cystic fibrosis, chronic bronchitis, bronchial pneumonia and asthma. Compositions are provided for use in the method comprising reporter gene constructs which are inducible by mucomones.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: October 24, 2000
    Assignee: The Regents of the University of California
    Inventors: Carol Basbaum, Marianne Gallup, Daizong Li, Assefa Gebremichael, Erin Gensch