Patents by Inventor Carol Colton

Carol Colton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTATIVE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20180133186
    Abstract: The present disclosure provides methods and formulations for the treatment of Alzheimer's disease in a subject in need thereof. The methods comprise administering to the subject an ornithine decarboxylase inhibitor such as alpha-difluoromethylornithine or a pharmaceutically acceptable salt in an amount effective to treat the disease.
    Type: Application
    Filed: November 14, 2017
    Publication date: May 17, 2018
    Inventor: Carol A. Colton
  • Treatment for neurodegenerative diseases
    Publication number: 20060281817
    Abstract: A method of treating a neurodegenerative disease in a subject in need thereof comprises: (a) administering the subject an ornithine decarboxylase inhibitor such as alpha-difluoromethylornithine or a pharmaceutically acceptable salt or prodrug thereof in an amount effective to treat the disease; and concurrently (b) administering the subject a polyamine or a pharmaceutically acceptable salt or prodrug thereof in an amount effective to reduce damage to the gastroinestinal tract of the subject by the ornithine decarboxylase inhibitor.
    Type: Application
    Filed: June 7, 2006
    Publication date: December 14, 2006
    Inventors: Carol Colton, Michael Vitek, Warren Strittmatter, Qing Xu, James Burke
  • Modulation of nitric oxide production
    Patent number: 6436996
    Abstract: A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an amount sufficient to combat the decrease of nitric oxide level associated with the presence of the APOE4 allele. Also disclosed is a method of increasing nitric oxide levels in cells in need thereof which comprises administering APOE to the cells in an amount sufficient to increase nitric oxide levels in the cells.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: August 20, 2002
    Assignees: Duke University, Georgetown University
    Inventors: Michael P. Vitek, Carol A. Colton