Patents by Inventor Carol F. Wichmann

Carol F. Wichmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotic agents
    Patent number: 5049546
    Abstract: A new antibiotic cyclic lipopeptide and a method of producing it are described. The agent has very high activity against human pathogens and is of very low mammalian toxicity.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: September 17, 1991
    Assignee: Merck & Co., Inc.
    Inventors: David F. Sesin, Jerrold M. Liesch, Jimmy M. Fountoulakis, Prakash S. Masurekar, Louis Kaplan, Carol F. Wichmann
  • Antibiotic agents
    Patent number: 5021403
    Abstract: A new antibiotic cyclic lipopeptide and a method of producing it are described. The agent has very high activity against human pathogens and is of very low mammalian toxicity.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: June 4, 1991
    Assignee: Merck & Co., Inc.
    Inventors: David F. Sesin, Jerrold M. Liesch, Jimmy M. Fountoulakis, Prakash S. Masurekar, Louis Kaplan, Carol F. Wichmann
  • Drug for treating manic depression
    Patent number: 4981980
    Abstract: Fermentation of a nutrient medium by a Hypomycetes fungus of the genus Memnoniella or Stachybotrys yields a product with a major component of structural formula I: ##STR1## which is an inositol monophosphate phosphatase inhibitor and thereby useful in the treatment of manic depression.
    Type: Grant
    Filed: September 14, 1989
    Date of Patent: January 1, 1991
    Assignee: Merck & Co., Inc.
    Inventors: Robert A. Giocobbe, Leeyuan Huang, Yu L. Kong, Yiu-Kuen T. Lam, Sagrario M. Del Val, Carol F. Wichmann, Deborah L. Zink
  • Antifungal fermentation product
    Patent number: 4931352
    Abstract: An antifungal agent produced by cultivation of a yet unidentified microorganism is a cyclic lipopeptide with very high activity against human pathogens and of very low mammalian toxicity. Its production and isolation are also described.
    Type: Grant
    Filed: June 7, 1989
    Date of Patent: June 5, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Robert A. Fromtling, Robert A. Giacobbe, Jerrold M. Liesch, Sagrario M. Del Val, Robert E. Schwartz, Carol F. Wichmann
  • Anti-inflammatory and antidegenerative compounds isolated from L-681,512
    Patent number: 4871727
    Abstract: There are disclosed anti-inflammatory and antidegenerative compounds which are natural products produced by cultivation of sail microorganism L-681,512 under controlled fermentation conditions.
    Type: Grant
    Filed: December 21, 1987
    Date of Patent: October 3, 1989
    Assignee: Merck & Co, Inc.
    Inventors: Richard W. Burg, Eugene L. Dulaney, Otto D. Hensens, Jerrold M. Liesch, John G. Ondeyka, Carol F. Wichmann
  • Antifugal tri-yne carbonates
    Patent number: 4806565
    Abstract: The invention relates to a novel tri-yne carbonate of formula I. Such compound can be produced by isolating it from the fermentation broth of ATCC-53614, ATCC-53615 OR ATCC-53616. The tri-yne carbonate has antifungal activity.
    Type: Grant
    Filed: May 26, 1987
    Date of Patent: February 21, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Otto D. Hensens, August J. Kempf, Robert E. Schwartz, Ruth S. Sykes, Carol F. Wichmann, Kenneth E. Wilson, Sheldon B. Zimmerman, Deborah L. Zink