Abstract: A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.

Abstract: Methods, systems, and computer readable media can be operable to facilitate an exchange of messages between an access point and a station, wherein the access point requests a unique identifier from the station. The station may either respond with a message declining to provide a unique identifier or respond with a message including a unique identifier to be used by the access point for the station. The response from the station may include additional limitations on the use of the unique identifier by the access point. The access point may enforce different policies against a station depending upon how the station responds to the unique identifier request.

Abstract: Methods, systems, and computer readable media can be operable to facilitate an exchange of messages between an access point and a station, wherein the access point requests a unique identifier from the station. The station may either respond with a message declining to provide a unique identifier or respond with a message including a unique identifier to be used by the access point for the station. The response from the station may include additional limitations on the use of the unique identifier by the access point. The access point may enforce different policies against a station depending upon how the station responds to the unique identifier request.

Abstract: Methods, systems, and computer readable media can be operable to facilitate an exchange of messages between an access point and a station, wherein the access point requests a unique identifier from the station. The station may either respond with a message declining to provide a unique identifier or respond with a message including a unique identifier to be used by the access point for the station. The response from the station may include additional limitations on the use of the unique identifier by the access point. The access point may enforce different policies against a station depending upon how the station responds to the unique identifier request.

Abstract: The present invention provides for kits and methods of treating hair in order to inhibit color fading and/or impart both shine- and condition-enhancing properties to colored hair, comprising a pre-treatment composition, a color-altering composition, a developer composition, a shampoo composition, a conditioner composition, and a post-treatment composition, wherein the post-treatment composition contains at least about 5% by weight of at least one oily component, based on the total weight of the post-treatment composition.

Abstract: The present invention provides for kits and methods of treating hair in order to inhibit color fading and/or impart both shine- and condition-enhancing properties to colored hair, comprising a pre-treatment composition, a color-altering composition, a developer composition, a shampoo composition, a conditioner composition, and a post-treatment composition, wherein the post-treatment composition contains at least about 5% by weight of at least one oily component, based on the total weight of the post-treatment composition.

Abstract: A hair coloring system includes at least one component of a hair coloring product and a container configured to contain the hair coloring product. The container may include a neck having a connecting portion and a top neck end. The system may further include an applicator tip for applying the hair coloring product to hair. The applicator tip may include a base portion configured to connect the applicator tip releasably to the connecting portion of the neck of the container and a nozzle portion extending from the base portion to a top end of the tip. The applicator tip and the container may be configured such that when the applicator tip is fully connected to the connecting portion of the neck of the container, an axial length from the top neck end to the top end of the tip is greater than about 1.9 inches.

Abstract: Products, packagings, display, and methods relating to hair coloring are disclosed. In some examples, a packaging for a hair coloring product includes a reflective portion configured to provide a reflection of a subject's hair color so as to permit the subject to compare the reflection of the subject's hair color to at least one representation of hair color. Certain examples may include multiple representations of hair after treatment with differing hair coloring products.

Abstract: The present inventors have discovered that pectin esterase is essential for plant growth. Specifically, the inhibition of pectin esterase gene expression resulted in seedlings that were damaged, short, and stunted at a very early growth stage. Thus, pectin esterase can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit pectin esterase expression or activity, comprising: contacting a compound with a pectin esterase and detecting the presence and/or absence of binding between said compound and said pectin esterase, or detecting a decrease in pectin esterase expression or activity. The methods of the invention are useful for the identification of herbicides.

Abstract: The present inventors have discovered that Biotin synthase (BS) is essential for plant growth. Specifically, inhibition of BS gene expression in plant seedlings results in severe chlorosis and reduced growth. Thus, BS can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit BS expression or activity, and as such, the methods of the invention are useful for the identification of herbicides.

Abstract: The present inventors have discovered that Flavanone 3-hydroxylase (“FHT”) is essential for plant growth. Specifically, the inhibition of FHT gene expression in plant seedlings results in small and chlorotic seedlings. Thus, FHT can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit FHT expression or activity. The present invention can be used to identify compounds having herbicide activity by contacting a compound with FHT and detecting the presence and/or absence of binding between the compound and the FHT, or alternatively, detecting a decrease in FHT expression or activity.

Abstract: The present invention provides methods and systems for presenting complex biological data in a display format that facilitates perception and apprehension by an operator. The invention presented herein leverages the bandwidth of the human perceptual system to enable operators of the invention to quickly recognize and identify trends and relationships within the data. The invention is useful in multiple applications, including applications in the agricultural, pharmaceutical, forensic, biotechnology and nutriceutical industries.

Abstract: The present inventors have discovered that 3-oxo-5-alpha-steroid 4-dehydrogenase (DET2) is essential for plant growth. Specifically, the inhibition of DET2 gene expression in plant seedlings resulted in seedlings that are shorter than controls and chlorotic. Thus, DET2 can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit DET2 expression or activity, comprising: contacting a compound with a DET2 and detecting the presence and/or absence of binding between said compound and said DET2, or detecting a decrease in DET2 expression or activity. The methods of the invention are useful for the identification of herbicides.

Abstract: The present inventors have discovered that LCBH is essential for plant growth. Specifically, the inhibition of LCBH gene expression in Arabidopsis results in reduced growth and abnormal development. Thus, LCBH is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of a LCBH in the presence and absence of a compound, where an alteration of LCBH activity in the presence of the compound indicates the compound as a candidate for a herbicide.

Abstract: The present inventors have discovered that Carbonic Anhydrase (CA) is essential for plant growth. Specifically, the inhibition of CA gene expression in plant seedlings results in reduced growth, and chlorosis. Thus, CA can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit CA expression or activity, comprising: contacting a compound with an CA and detecting the presence and/or absence of binding between said compound and said an CA, or detecting a change in CA expression or activity. The methods of the invention are useful for the identification of herbicides.

Abstract: The present inventors have discovered that ferredoxin NADP oxidoreductase (FNR) is essential for plant growth. Specifically, the inhibition of FNR gene expression in plant seedlings resulted in seedlings that looked pale and very stunted. Thus, FNR can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit FNR expression or activity, comprising: contacting a compound with a FNR and detecting the presence and/or absence of binding between the compound and the FNR, or detecting a decrease in FNR expression or activity. The methods of the invention are useful for the identification of herbicides.

Abstract: The present inventors have discovered that CAX1-like H+/Ca+2 antiporter is essential for plant growth. Specifically, the inhibition of CAX1-like H+/Ca+2 antiporter gene expression in plant seedlings results in reduced growth and abnormal development. Thus, CAX1-like H+/Ca+2 antiporter is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of a CAX1-like H+/Ca+2 antiporter in the presence and absence of a compound, where an alteration of CAX1-like H+/Ca+2 antiporter activity in the presence of the compound indicates the compound as a candidate for a herbicide.

Abstract: The present inventors have discovered that NADPH:protochlorophyllide oxidoreductase (POR) is essential for plant growth. Specifically, the inhibition of POR gene expression in plant seedlings results in reduced growth and chlorosis. Thus, POR is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of a POR in the presence and absence of a compound, wherein an alteration of POR activity in the presence of the compound indicates the compound as a candidate for a herbicide.

Abstract: The present inventors have discovered that Lipid Transfer Protein (LTP) is essential for plant growth. Specifically, the inhibition of LTP gene expression in plant seedlings results in reduced growth and chlorosis. Thus, LTP is useful as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of herbicides by measuring the activity of an LTP in the presence and absence of a compound, wherein an alteration of LTP activity in the presence of the compound indicates the compound as a candidate for a herbicide.