Patents by Inventor Carol Kamps-Holtzapple

Carol Kamps-Holtzapple has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies to ceftiofur
    Patent number: 5908781
    Abstract: Hybridoma cell lines have been generated which produce and secrete monoclonal antibodies which selectively bind to the ceftiofur. These hybridomas may be obtained by using as an immunization agent or immunogen, desfuroyl ceftiofur which has been conjugated to an immunogenic carrier. Ceftiofur in biological samples may be detected and quantified by contacting the sample with the antibodies to form a ceftiofur/antibody immunocomplex when ceftiofur is present, which immunocomplex may then be detected. The monoclonal antibodies may also be incorporated into kits for the detection and quantification of ceftiofur.
    Type: Grant
    Filed: December 10, 1996
    Date of Patent: June 1, 1999
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Larry H. Stanker, Beate G. Rose, John R. DeLoach, Carol Kamps Holtzapple
  • Monoclonal antibodies to hygromycin B and the method of making the same
    Patent number: 5620890
    Abstract: Hybridoma cell lines have been produced which secrete monoclonal antibodies that bind hygromycin B and are effective to detect hygromycin B levels as low as about 0.7 ppm. These monoclonal antibodies may be used for the detection and quantitative determination of trace amounts of hygromycin B in samples, especially in animal tissue and feed material.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: April 15, 1997
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Carol Kamps-Holtzapple, Larry H. Stanker, John R. DeLoach