Patents by Inventor Carol M. Taylor

Carol M. Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alpha-aminophosphonates and processes for their preparation
    Patent number: 5824809
    Abstract: Novel .alpha.-aminophosphonates are provided along with processes and intermediates for their preparation. In preferred embodiments, scalemic .alpha.-aminophosphonates are prepared by the stereoselective addition of phosphite salts to chiral imines.
    Type: Grant
    Filed: April 15, 1996
    Date of Patent: October 20, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Amos B. Smith, III, Kraig M. Yager, Carol M. Taylor
  • Solution and solid-phase formation of glycosidic linkages
    Patent number: 5700916
    Abstract: The invention relates to methods that permit the rapid construction of oligosaccharides and other glycoconjugates. Methods for forming multiple glycosidic linkages in solution in a single step are disclosed. The invention takes advantage of the discovery that the relative reactivity of glycoside residues containing anomeric sulfoxides and nucleophilic functional groups can be controlled. In another aspect of the invention, the reactivity of activated anomeric sugar sulfoxides is utilized in a solid phase method for the formation of glycosidic linkages. The methods disclosed may be applied to the preparation of specific oligosaccharides and other glycoconjugates, as well as to the preparation of glycosidic libraries comprising mixtures of various oligosaccharides, including glycoconjugates, which can be screened for biological activity.
    Type: Grant
    Filed: July 27, 1994
    Date of Patent: December 23, 1997
    Assignee: Trustees of Princeton University
    Inventors: Daniel E. Kahne, Robert A. Goodnow, Jr., Carol M. Taylor, Lin Yan
  • .alpha.-aminophosphonates
    Patent number: 5508463
    Abstract: Novel .alpha.-aminophosphonates are provided along with processes and intermediates for their preparation. In preferred embodiments, scalemic .alpha.-aminophosphonates are prepared by the stereoselective addition of phosphite salts to chiral imines.
    Type: Grant
    Filed: March 17, 1994
    Date of Patent: April 16, 1996
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Amos B. Smith, III, Kraig M. Yager, Carol M. Taylor