Patents by Inventor Carol Readhead

Carol Readhead has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NON-INVASIVE LASER SPECKLE IMAGING OF EXTRA-EMBRYONIC BLOOD VESSELS
    Publication number: 20250265710
    Abstract: Laser speckle contrast imaging techniques that apply a temporal sliding window to a sequence of speckle frames of an avian egg to determine overlapping sets of speckle frames used to reconstruct a sequence of extraembryonic blood vessel images (e.g., movie) showing blood flow dynamics, and where input to a machine learning model based on the overlapping sets of speckle frames can be used to predict the developmental stage of the avian egg, and where the overlapping sets of speckle frames can be used in drug screening.
    Type: Application
    Filed: February 18, 2025
    Publication date: August 21, 2025
    Inventors: Zhenyu Dong, Simon Mahler, Carol Readhead, Changhuei Yang
  • In vitro platform and methods for culturing embryos for implantation
    Patent number: 10213282
    Abstract: A mammalian in vitro system for culturing an embryo includes a collagen or fibrin matrix and endometrial and/or stromal cells. The in vitro platforms and methods according to embodiments of the invention allow for in vitro embryonic development (including implantation) prior to transfer of the embryo complex in vivo for further development.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: February 26, 2019
    Assignee: California Institute of Technology
    Inventors: Samuel Ojosnegros Martos, Carol Readhead, Ayelet Lesman
  • IN VITRO PLATFORM AND METHODS FOR CULTURING EMBRYOS FOR IMPLANTATION
    Publication number: 20150305774
    Abstract: A mammalian in vitro system for culturing an embryo includes a collagen or fibrin matrix and endometrial and/or stromal cells. The in vitro platforms and methods according to embodiments of the invention allow for in vitro embryonic development (including implantation) prior to transfer of the embryo complex in vivo for further development.
    Type: Application
    Filed: April 28, 2015
    Publication date: October 29, 2015
    Inventors: Samuel Ojosnegros Martos, Carol Readhead, Ayelet Lesman
  • Genetic modification of male germ cells for generation of transgenic species & genetic therapies
    Publication number: 20050034177
    Abstract: Disclosed is an in vivo method of incorporating exogenous genetic material into the genome of a non-human vertebrate, including but not limited to a non-human mammal.
    Type: Application
    Filed: May 10, 2004
    Publication date: February 10, 2005
    Inventors: Carol Readhead, Robert Winston
  • Transgenic mouse model for pituitary disorders associated with LIF overexpression and/or GH underexpression, and its use for testing therapeutic drugs for the conditions
    Patent number: 5824838
    Abstract: Recombinant transgenic mice expressing leukemia inhibitory factor (LIF) in the pituitary. The transgenic mice of the invention are suitable for use as animal models of pituitary disorders, as well as for identifying compounds which stimulate growth hormone production, for the treatment of physiological disorders associated with growth retardation and pituitary developmental retardation disorders, such as chraneopharyngioma, and pituitary cysts, among others.
    Type: Grant
    Filed: May 9, 1996
    Date of Patent: October 20, 1998
    Assignee: Cedars-Sinai Medical Center
    Inventors: Shlomo Melmed, Sadanori Akita, Carol Readhead