Patents by Inventor Carol Ward

Carol Ward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETERMINATION OF RESPONDERS TO CHEMOTHERAPY
    Publication number: 20100196931
    Abstract: The present invention relates to a method of determining whether a biological sample comprising human lung cancer cells is sensitive to a combination of an epidermal growth factor receptor inhibitor and a chemotherapeutic agent by determining the overexpression of a phosphorylated AKT protein and/or a phosphorylated MAPK protein in the biological sample. The invention is also related to methods for deriving a candidate agent or for selecting a composition for inhibiting the progression of lung cancer in a patient wherein a phosphorylated AKT protein and/or a phosphorylated MAPK protein is used.
    Type: Application
    Filed: November 19, 2009
    Publication date: August 5, 2010
    Inventors: Ulrich Brennscheidt, Otmar Herrgott, Astrid Heller, Verena Lutz, Joachim Moecks, Carol Ward
  • Determination of responders to chemotherapy
    Patent number: 7655414
    Abstract: The present invention relates to a method of determining whether a biological sample comprising human lung cancer cells is sensitive to a combination of an epidermal growth factor receptor inhibitor and a chemotherapeutic agent by determining the overexpression of a phosphorylated AKT protein and/or a phosphorylated MAPK protein in the biological sample. The invention is also related to methods for deriving a candidate agent or for selecting a composition for inhibiting the progression of lung cancer in a patient wherein a phosphorylated AKT protein and/or a phosphorylated MAPK protein is used.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: February 2, 2010
    Assignee: Hoffman La-Roche Inc.
    Inventors: Ulrich Brennscheidt, Otmar Herrgott, legal representative, Astrid Heller, Verena Lutz, Joachim Moecks, Carol Ward
  • Determination of responders to chemotherapy
    Publication number: 20070054330
    Abstract: The present invention relates to a method of determining whether a biological sample comprising human lung cancer cells is sensitive to a combination of an epidermal growth factor receptor inhibitor and a chemotherapeutic agent by determining the overexpression of a phosphorylated AKT protein and/or a phosphorylated MAPK protein in the biological sample. The invention is also related to methods for deriving a candidate agent or for selecting a composition for inhibiting the progression of lung cancer in a patient wherein a phosphorylated AKT protein and/or a phosphorylated MAPK protein is used.
    Type: Application
    Filed: May 10, 2006
    Publication date: March 8, 2007
    Inventors: Ulrich Brennscheidt, Otmar Herrgott, Astrid Heller, Verena Lutz, Joachim Moecks, Carol Ward
  • Process of making human nerve growth factor
    Patent number: 5272063
    Abstract: A method for the construction of recombinant DNA molecules capable of producing biologically active human nerve growth factor (hNGF) in insect cells is disclosed. Expression of the mature protein is achieved using the baculovirus expression system. The biologically active hNGF so produced is potentially of value in the treatment of patients suffering from Alzheimer's Disease and other neurological disorders.
    Type: Grant
    Filed: July 20, 1989
    Date of Patent: December 21, 1993
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Hardy W. Chan, Jim W. Barnett, Preston A. Baecker, Hela Bursztyn-Pettegrew, Binh T. Nguyen, Carol Ward