Abstract: Systems and methods for operatively coupling a payment card to a customer database are disclosed. A financial institution computing system includes a customer database, a network interface circuit enabling the financial institution computing system to exchange information over a network, and a data circuit. The customer database stores financial information and non-financial information received from at least one merchant computing system. The data circuit receives non-financial information associated with a customer from at least one merchant computing system and updates the non-financial information in the customer database. The data circuit receives a transaction request generated by the customer at a transaction terminal using a payment card corresponding to a payment card account.

Abstract: A method comprising co-administering to a subject having cancer, suspected of having cancer, or at risk of developing cancer: a therapeutically effective amount of at least one compound (a) selected from (a)(i) a nitroalkene fatty acid, (a)(ii) an unsaturated fatty acid having an electron withdrawing group, a leaving group, and a carbon-carbon double bond disposed between the electron withdrawing group and the leaving group, (a)(iii) a thiolated nitro fatty acid, or (a)(iv) a dicarboxylic acid compound containing an electron withdrawing group; and a therapeutically effective amount of at least one anti-neoplastic agent (b), wherein the cancer is a cancer with hereditary etiology of defects in DNA repair genes, a cancer with a high rate of spontaneous genomic instability, a cancer that responds well to DNA damaging agent(s), or a cancer that responds well to a combination of DNA damaging agent(s) with immunotherapy.

Abstract: A drug screening device is provided. A method of determining optimal drug concentrations and efficacy in a patient using the device are provided. A method of determining effective chemotherapeutic drugs and effective concentrations thereof using the device is provided. Also, a method of determining safety and efficacy of drugs using the device is provided.

Abstract: Systems and methods for operatively coupling a payment card to a customer database are disclosed. A financial institution computing system includes a customer database, a network interface circuit enabling the financial institution computing system to exchange information over a network, and a data circuit. The customer database stores financial information and non-financial information received from at least one merchant computing system. The data circuit receives non-financial information associated with a customer from at least one merchant computing system and updates the non-financial information in the customer database. The data circuit receives a transaction request generated by the customer at a transaction terminal using a payment card corresponding to a payment card account.