Patents by Inventor Carolin Daniel

Carolin Daniel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIVIRAL VACCINES USING SPHERICAL NUCLEIC ACIDS
    Publication number: 20220288181
    Abstract: Spherical Nucleic Acids (SNAs) are chemically well-defined nanoscale architectures comprised of nucleic acids densely arranged around a spherical nanoparticle core in a highly oriented fashion. SNAs are highly modular structures produced by chemical synthesis and programmed assembly, allowing for their rapid modification to incorporate novel viral antigens. The present disclosure provides a SNA comprising (a) a nanoparticle core; (b) a shell of oligonucleotides attached to the external surface of the nanoparticle core, the shell of oligonucleotides comprising one or more immunostimulatory oligonucleotides; and (c) a viral antigen encapsulated in the nanoparticle core.
    Type: Application
    Filed: March 1, 2022
    Publication date: September 15, 2022
    Inventors: Chad A. Mirkin, Michelle Hope Teplensky, Max Everett Distler, Caroline Danielle Kusmierz, Cassandra Elizabeth Callmann
  • PREVENTION OF TYPE 1 DIABETES BY TREG VACCINATION WITH AN INSULIN MIMETOPE
    Publication number: 20160175412
    Abstract: The invention involves methods and products for inducing Treg cells for immune suppression in connection with autoimmune disease and transplant rejection.
    Type: Application
    Filed: August 25, 2015
    Publication date: June 23, 2016
    Inventors: HARALD VON BOEHMER, CAROLIN DANIEL
  • PREVENTION OF TYPE 1 DIABETES BY TREG VACCINATION WITH AN INSULIN MIMETOPE
    Publication number: 20110311536
    Abstract: The invention involves methods and products for inducing Treg cells for immune suppression in connection with autoimmune disease and transplant rejection.
    Type: Application
    Filed: June 10, 2011
    Publication date: December 22, 2011
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Harald von Boehmer, Carolin Daniel