Patents by Inventor Carolina Guibentif

Carolina Guibentif has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS, SYSTEMS, FACTORS, AND MEDIA FOR REDUCTION OF CELLULAR STRESS AND REACTIVE OXYGEN SPECIES
    Publication number: 20200095551
    Abstract: The present invention relates to methods, systems, factors, and media for the reduction of cellular stress and reduction of the amount reactive oxygen species. Embodiments of the invention reduce cellular stress by treating cells with a variety of molecules, such as certain inhibitors. Some embodiments may reduce the amount of reactive oxygen species in cell media through the use of scavengers.
    Type: Application
    Filed: March 17, 2017
    Publication date: March 26, 2020
    Inventors: Niels-Bjarne Woods, Roger Emanuel RÖNN, Carolina GUIBENTIF, Shobhit SAXENA
  • COMPOSITIONS AND METHODS FOR DIFFERENTIATING PLURIPOTENT STEM CELLS INTO PRIMITIVE BLOOD CELLS AND USES THEREOF
    Publication number: 20160369235
    Abstract: Compositions and methods that employ various combinations of such factors as retinoic acid signaling inhibitors, antioxidants, BMP4, VEGF, prostaglandin E2 pathway stimulants, TPO, SCF, FLT-3, EPO, TGF?1, p38 MAPK inhibitors, beta adrenergic receptor agonists, cell cycle inhibitors, RXR agonists, Cripto, and chromatin remodelers to drive differentiation of pluripotent stem cells towards primitive blood cells. Uses of such primitive blood cells are provided.
    Type: Application
    Filed: August 29, 2016
    Publication date: December 22, 2016
    Applicant: Primorigen Biosciences, Inc.
    Inventors: Niels-Bjarne Woods, Roger Ronn, Carolina Guibentif
  • Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof
    Patent number: 9428732
    Abstract: Compositions and methods that employ various combinations of such factors as retinoic acid signaling inhibitors, antioxidants, BMP4, VEGF, prostaglandin E2 pathway stimulants, TPO, SCF, FLT-3, EPO, TGF?1, p38 MAPK inhibitors, beta adrenergic receptor agonists, cell cycle inhibitors, RXR agonists, Cripto, and chromatin remodelers to drive differentiation of pluripotent stem cells towards primitive blood cells. Uses of such primitive blood cells are provided.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: August 30, 2016
    Assignee: Primorigen Biosciences, Inc.
    Inventors: Niels-Bjarne Woods, Roger Ronn, Carolina Guibentif