Patents by Inventor Carolina HAGER RIBEIRO

Carolina HAGER RIBEIRO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human antibody and fragments thereof for use in the treatment of gastric cancer (GC) and other types of tumours expressing the MICA protein (MHC class I chain-related protein A gene)
    Patent number: 11518811
    Abstract: A bivalent, anti-MICA human monoclonal antibody formed by two or more heavy and light chains with a variable immunoglobulin domain neutralises the MICA protein in its soluble state and opsonises tumour cells expressing the antigen, stimulating adaptive immunity in the treatment of gastric cancer or other types of cancer in which the tumour cells express MICA in the soluble form or abundantly on their surface.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: December 6, 2022
    Inventors: María Carmen Molina Sampayo, Juan Carlos Aguillón Gutierrez, Carolina Hager Ribeiro, Roberto Aquiles Zúñiga Olate, Norberto Andrés Collazomuñoz, Lorenzo Leiva Araya, Matías Fernando Gutierrez Gonzalez, Jaime Camilo Teneb Lobos, Alfonso Enrique Romero Trujillo, Bastían Nicolás Jerez Donoso
  • HUMAN ANTIBODY AND FRAGMENTS THEREOF FOR USE IN THE TREATMENT OF GASTRIC CANCER (GC) AND OTHER TYPES OF TUMOURS EXPRESSING THE MICA PROTEIN (MHC CLASS I CHAIN-RELATED PROTEIN A GENE)
    Publication number: 20210139593
    Abstract: A bivalent, anti-MICA human monoclonal antibody formed by two or more heavy and light chains with a variable immunoglobulin domain neutralises the MICA protein in its soluble state and opsonises tumour cells expressing the antigen, stimulating adaptive immunity in the treatment of gastric cancer or other types of cancer in which the tumour cells express MICA in the soluble form or abundantly on their surface.
    Type: Application
    Filed: December 27, 2018
    Publication date: May 13, 2021
    Inventors: María Carmen MOLINA SAMPAYO, Juan Carlos AGUILLÓN GUTIERREZ, Carolina HAGER RIBEIRO, Roberto Aquiles ZÚÑIGA OLATE, Norberto Andrés COLLAZOMUÑOZ, Lorenzo LEIVA ARAYA, Matías Fernando GUTIERREZ GONZALEZ, Jaime Camilo TENEB LOBOS, Alfonso Enrique ROMERO TRUJILLO, Bastián Nicolás JEREZ DONOSO