Abstract: The present invention relates to an X-ray imaging system (10), comprising a radiograph X-ray attenuation image acquisition unit (20), at least one sensor (30), and a processing unit (40). The radiograph X-ray attenuation image acquisition unit is configured to acquire a radiograph image of a patient. The radiograph X-ray attenuation image acquisition unit is configured to provide the radiograph image to the processing unit. The at least one sensor is configured to acquire sensor data of the patient. The at least one sensor is configured to provide the sensor data to the processing unit. The processing unit is configured to determine a magnitude and direction of movement of the patient during a time of acquisition of the radiograph image, the determination comprising utilization of the sensor data.

Abstract: A system (30) and method for detecting or predicting toxicity induced by radiation therapy. A device (34) is configured for determining polypeptide biomarkers present in a urine sample. At least one processor (36) is programmed to detect or predict radiation toxicity based on one or more polypeptide biomarkers determined to be in the urine sample.

Abstract: The invention relates to a device (10) for determining spatially dependent x-ray flux degradation and photon spectral change, a system (1) for determining spatially dependent x-ray flux degradation and photon spectral change for an x-ray tube (20), a method for spatially dependent x-ray flux degradation and photon spectral change for an x-ray tube (20), a computer program element for controlling such device (10) or system (1) for performing such method and a computer readable medium having stored such computer program element. The device (10) for determining spatially dependent x-ray flux degradation and photon spectral change comprises an acquisition unit (11), a processing unit (12), a calculation unit (13), and a combination unit (14). The acquisition unit (11) is configured to acquire x-ray flux degradation data for the x-ray tube (20). The processing unit (12) is configured to process the x-ray flux degradation data into spatially dependent flux degradation data.

Abstract: The present invention relates to a device (34) and a method (70) for determining a status of an X-ray tube (10) of an X-ray system (36). Due to ageing and/or wear of the X-ray tube, the spectrum of the X-ray radiation (30) provided by the X-ray tube may change over the operation time of the X-ray tube. The present invention therefore suggests evaluating spectrally different values detected with an X-ray detector arrangement (32) of the X-ray system. A reference data set representing a reference condition of the X-ray tube by a plurality of spectrally different reference-values (44) and a working data set representing an aged condition of the X-ray tube by a plurality of spectrally different working-values (46) of detected X-ray radiation are used to determine an equivalent filtration function for an filtration material influencing a source X-ray radiation (26) emitted by an anode (16) of the X-ray tube.

Abstract: A system for interventional brachytherapy for generating data to be used directly for therapy and/or for therapy planning includes a radiation source which irradiates tissue of a patient and one or more radiation detectors which detect radiation delivered to the patient and generate radiation dosage data indicative thereof. One or more position sensors determine the position of the radiation source and a localization unit, in communication with the one or more position sensors, generates position data indicative of the position of the radiation source. An image database stores one or more anatomical images of the patient. A dose calculation unit which co-registers the one or more anatomical images with the positional and radiation dosage data and generates dose monitoring data based on the co-registration.

Abstract: The present invention relates to a radiation detector, in particular a direct conversion radiation detector. To provide for simple distribution of provided high voltage the radiation detector comprises a plurality of detector modules (10, 20) arranged adjacent to each other. Each detector module comprises a sensor layer (14, 24) for converting incident radiation (100) into electrical charges, a first electrode (15, 25) deposited on a first surface of the sensor layer facing the incident radiation (100), a second electrode (16, 26) deposited on a second surface of the sensor layer opposite the first surface, a readout electronics (12, 22) in electrical contact with the second electrode, and a carrier (13, 23) for carrying the sensor layer and the readout electronics.

Abstract: An apparatus comprises: a database (30) storing medical data including image medical data and non-image medical data for a plurality of patients; a digital processor (40) configured to (i) generate a features vector (56) comprising features indicative of a patient derived from patient medical data stored in the database including both patient image medical data and patient non-image medical data and (ii) perform multivariate analysis (64) on a features vector generated for a patient of interest to determine a proposed diagnosis for the patient of interest; and a user interface (42) configured to output a human perceptible representation of the proposed diagnosis for the patient of interest.

Abstract: The present invention relates to an apparatus for assessing medical device quality. It is described to provide (210) at least one report associated with at least one medical image acquired by a medical device, wherein a report is associated with a corresponding medical image. The at least one report is analyzed and at least one image quality parameter is generated (220), wherein an image quality parameter is associated with a 5 corresponding report. The at least one image quality parameter is assessed and generating alert information relating to the medical device is generated (230).

Abstract: The present invention relates to a radiation detector, in particular a direct conversion radiation detector. To provide for simple distribution of provided high voltage the radiation detector comprises a plurality of detector modules (10, 20) arranged adjacent to each other. Each detector module comprises a sensor layer (14, 24) for converting incident radiation (100) into electrical charges, a first electrode (15, 25) deposited on a first surface of the sensor layer facing the incident radiation (100), a second electrode (16, 26) deposited on a second surface of the sensor layer opposite the first surface, a readout electronics (12, 22) in electrical contact with the second electrode, and a carrier (13, 23) for carrying the sensor layer and the readout electronics.

Abstract: The invention relates to a device (10) for determining spatially dependent x-ray flux degradation and photon spectral change, a system (1) for determining spatially dependent x-ray flux degradation and photon spectral change for an x-ray tube (20), a method for spatially dependent x-ray flux degradation and photon spectral change for an x-ray tube (20), a computer program element for controlling such device (10) or system (1) for performing such method and a computer readable medium having stored such computer program element. The device (10) for determining spatially dependent x-ray flux degradation and photon spectral change comprises an acquisition unit (11), a processing unit (12), a calculation unit (13), and a combination unit (14). The acquisition unit (11) is configured to acquire x-ray flux degradation data for the x-ray tube (20). The processing unit (12) is configured to process the x-ray flux degradation data into spatially dependent flux degradation data.

Abstract: The present invention relates to a device (34) and a method (70) for determining a status of an X-ray tube (10) of an X-ray system (36). Due to ageing and/or wear of the X-ray tube, the spectrum of the X-ray radiation (30) provided by the X-ray tube may change over the operation time of the X-ray tube. The present invention therefore suggests evaluating spectrally different values detected with an X-ray detector arrangement (32) of the X-ray system. A reference data set representing a reference condition of the X-ray tube by a plurality of spectrally different reference-values (44) and a working data set representing an aged condition of the X-ray tube by a plurality of spectrally different working-values (46) of detected X-ray radiation are used to determine an equivalent filtration function for an filtration material influencing a source X-ray radiation (26) emitted by an anode (16) of the X-ray tube.

Abstract: The invention relates to a system (31) for generating spectral computed tomography projection data. A spectral projection data generation device (6) comprising an energy-resolving detector generates spectral computed tomography projection databased on polychromatic radiation (4), which has been provided by a radiation device (2), after having traversed an examination zone (5), and a reference values generation device generates energy-dependent reference values based on radiation, which has not traversed the examination zone. A spectral parameter providing unit (12) provides a spectral parameter being indicative of a spectral property of the radiation device based on the energy-dependent reference values.

Abstract: The invention relates to a system (31) for generating spectral computed tomography projection data. A spectral projection data generation device (6) comprising an energy-resolving detector generates spectral computed tomography projection databased on polychromatic radiation (4), which has been provided by a radiation device (2), after having traversed an examination zone (5), and a reference values generation device generates energy-dependent reference values based on radiation, which has not traversed the examination zone. A spectral parameter providing unit (12) provides a spectral parameter being indicative of a spectral property of the radiation device based on the energy-dependent reference values.

Abstract: An energy application apparatus applies energy to an object. The object (2), such as a tumor which has absorbed a radioisotope tracer, defines a location (3) of radioactive material. A location detection unit detects the location with the radioactive material. An x-ray unit applies x-rays to the detected location of the object. Since the location, to which energy should be applied, includes radioactive material, this location can be accurately detected by using the location detection unit. Moreover, since the application of the x-rays can be well controlled by controlling, for example, the intensity and the energy spectrum of the x-rays, energy can be accurately applied to the accurately detected location. The overall process of applying energy to the object can therefore be performed with increased accuracy.

Abstract: A system for interventional brachytherapy for generating data to be used directly for therapy and/or for therapy planning includes a radiation source which irradiates tissue of a patient and one or more radiation detectors which detect radiation delivered to the patient and generate radiation dosage data indicative thereof. One or more position sensors determine the position of the radiation source and a localization unit, in communication with the one or more position sensors, generates position data indicative of the position of the radiation source. An image database stores one or more anatomical images of the patient.

Abstract: A system (30) and method for detecting or predicting toxicity induced by radiation therapy. A device (34) is configured for determining polypeptide biomarkers present in a urine sample. At least one processor (36) is programmed to detect or predict radiation toxicity based on one or more polypeptide biomarkers determined to be in the urine sample.

Abstract: A method for treating a surface layer (3) of a device (1) consisting of alumina and a corresponding device (1) are proposed. The method comprises providing the device (1) with the surface layer (3) to be treated being exposed and heating the surface layer (3) of the device (1) in an oxygen-depleted atmosphere comprising e.g. one of an inert gas, nitrogen, hydrogen, argon and a combination thereof to a temperature higher than 1000° C., preferably higher than 1700° C. for a duration of preferably more than 2 hours. Due to such treatment, a superficial layer region (7) comprised in the surface layer (3) may obtain a significantly reduced electrical resistivity which is assumed to be the result of chemically reducing this superficial layer region (7). Such reduced superficial electrical resistivity may advantageously serve for example in components of electron beam devices such as x-ray tube components for preventing any charge build-up.

Abstract: A method for radiotherapy monitoring is provided. The method comprises calculation of treatment-guiding indices of side-effects based on processing image derived descriptors and measurement values of selected disease specific biomarkers and optionally questionnaire data. A computer program product is also provided.

Abstract: Nuclear Imaging System The invention relates to a nuclear imaging system (1) for imaging an object (3) in an examination region. Multiple x-rays sources (2) generate first radiation being x-ray radiation (5), wherein the x-ray sources are arranged such that the x-ray radiation is indicative of a property of the object. A detection unit (6) detects second radiation (7) from a nuclear element (8), after the second radiation has the traversed the object, and the first radiation generated by the multiple x-ray sources, thereby inherently registering the detection of the first radiation and the second radiation. A reconstruction unit (9) reconstructs a corrected nuclear image of the object based on the detected first radiation and the detected second radiation, wherein the nuclear image is corrected with respect to the property of the object and, because of the inherent registration, does not comprise image artifacts caused by registration errors.

Abstract: A method includes obtaining an image of a region of interest of a subject, wherein the image is generated with image data produced by an imaging system used to scan the subject, obtaining a signal indicative of a physiological state of the subject before the scan, and displaying both the image and data indicative of the physiological state. In another aspect, a method includes correcting, via a processor, a tracer uptake value for a target region of interest based on a tracer uptake correction factor.