Patents by Inventor Carolina Solange ILKOW

Carolina Solange ILKOW has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICRORNA-BASED COMPOSITIONS AND METHODS USED IN DISEASE TREATMENT
    Publication number: 20240026380
    Abstract: The present disclosure provides a miRNA hairpin that, when processed by a virus-infected cell, increases the therapeutic effectiveness of the virus. The present disclosure also provides a virus encoding such a miRNA hairpin. The present disclosure also provides pre-miRNAs that, when processed by a virus-infected cell, increase extracellular vesicle secretion of the encoded miRNA hairpin by the virus-infected cell.
    Type: Application
    Filed: June 28, 2023
    Publication date: January 25, 2024
    Inventors: Carolina Solange ILKOW, John Cameron BELL, Victoria Ann MAHER, Briana Livia Rollande SAMSON
  • MicroRNA-based compositions and methods used in disease treatment
    Patent number: 11739350
    Abstract: The present disclosure provides a miRNA hairpin that, when processed by a virus-infected cell, increases the therapeutic effectiveness of the virus. The present disclosure also provides a virus encoding such a miRNA hairpin. The present disclosure also provides pre-miRNAs that, when processed by a virus-infected cell, increase extracellular vesicle secretion of the encoded miRNA hairpin by the virus-infected cell.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: August 29, 2023
    Assignee: OTTAWA HOSPITAL RESEARCH INSTITUTE
    Inventors: Carolina Solange Ilkow, John Cameron Bell, Victoria Ann Maher, Briana Livia Rollande Samson
  • MICRORNA-BASED COMPOSITIONS AND METHODS USED IN DISEASE TREATMENT
    Publication number: 20210032662
    Abstract: The present disclosure provides a miRNA hairpin that, when processed by a virus-infected cell, increases the therapeutic effectiveness of the virus. The present disclosure also provides a virus encoding such a miRNA hairpin. The present disclosure also provides pre-miRNAs that, when processed by a virus-infected cell, increase extracellular vesicle secretion of the encoded miRNA hairpin by the virus-infected cell.
    Type: Application
    Filed: April 10, 2019
    Publication date: February 4, 2021
    Inventors: Carolina Solange ILKOW, John Cameron BELL, Victoria Ann MAHER, Briana Livia Rollande SAMSON
  • Compositions and methods for enhancing virus replication
    Patent number: 10604741
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: March 31, 2020
    Assignee: TURNSTONE LIMITED PARTNERSHIP
    Inventors: Carolina Solange Ilkow, Fabrice Le Boeuf, John Cameron Bell, Jean-Simon Diallo, Rozanne Arulanandam
  • Compositions and methods for enhancing virus replication
    Patent number: 10066214
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: September 4, 2018
    Assignee: Turnstone Limited Partnership
    Inventors: Carolina Solange Ilkow, Fabrice Le Boeuf, John Cameron Bell, Jean-Simon Diallo, Rozanne Arulanandam
  • COMPOSITIONS AND METHODS FOR ENHANCING VIRUS REPLICATION
    Publication number: 20180237753
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Application
    Filed: March 13, 2018
    Publication date: August 23, 2018
    Inventors: Carolina Solange ILKOW, Fabrice LE BOEUF, John Cameron BELL, Jean-Simon DIALLO, Rozanne ARULANANDAM
  • COMPOSITIONS AND METHODS FOR ENHANCING VIRUS REPLICATION
    Publication number: 20160130563
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 12, 2016
    Inventors: Carolina Solange ILKOW, Fabrice LE BOEUF, John Cameron BELL, Jean-Simon DIALLO, Rozanne ARULANANDAM