Abstract: The present disclosure pertains to therapeutic hydrogels that comprise an anionic polysaccharide crosslinked by a branched polyamine, wherein the branched polyamine comprises at least two primary amine groups, more typically at least three primary amine groups. The present disclosure also pertains to medical compositions that comprise such therapeutic hydrogels and to methods of medical treatment in which such therapeutic hydrogels are delivered to a patient in need of medical treatment.

Abstract: A medical system having a medical tool, including a handle, a shaft extending from the handle and defining a lumen, a wire attached to and extending from the handle through the lumen, expandable elements at a distal end of the wire. An electrical generator is coupled to a proximal end of the wire and supplies a first waveform to the wire and the expandable elements as the expandable elements expand from an unexpanded state to an expanded state within a tissue. The electrical generator supplies a second waveform to the wire and the expandable elements when the expandable elements are in the expanded state within the tissue. The first waveform cuts tissue, the second waveform ablates tissue using radiofrequency ablation or irreversible electroporation.

Abstract: Various embodiments are generally directed to fluid container adapters that couple with a fluid container, so to enable access to the contents of the fluid container, such as from an endoscopic system via a tubing set. Several embodiments are particularly directed to a fluid container adapter that can couple with an opening in a variety of fluid containers to place one or more tubes in fluid communication with an interior of any particular one of the variety of fluid containers.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to devices, systems, and methods for controlled volume ablation of tissue. In one example, a catheter may include an elongated member having a distal end extending along a longitudinal axis. A first electrode may extend along the elongated member. The first electrode may have a distal portion arranged on a circumferential surface about the longitudinal axis at the distal end. A second electrode may extend along the elongated member. The second electrode may have a distal portion arranged on the circumferential surface about the longitudinal axis at the distal end of the elongated member. A sheath may be slidably disposed about the elongated member. The sheath may be configured to change position by sliding along the member to insulate a portion of one or both of the first and second electrode.

Abstract: Regulating cardiac activity may include pacing the patient's heart at a starting pacing rate and instigating an intrinsic heart beat search algorithm that includes pacing at a reduced rate for a period of time and capturing electrical signals representative of cardiac electrical activity while pacing at the reduced rate in order to determine a presence or absence of intrinsic heart beats. If intrinsic heart beats are not detected, the heart may be paced at a further reduced rate for a period of time. If intrinsic beats are detected, the heart may be paced again at the starting pacing rate. This may continue until intrinsic heart beats are detected or until a lower search rate limit is reached. Diagnostic data may be collected at each stage and transmitted to a display device for analysis by a physician or the like.

Abstract: A medical cleaning valve (or cleaning valve) may be configured to provide cleaning functionality to air and water channels of an endoscope. One or more embodiments described herein may include cleaning valves with features and/or components that facilitate differentiating them from procedural valves. In some embodiments, valves may be made from a limited number of parts and materials, to limit their cost. For example, multiple seals may be formed as a single component, such as via overmolding. In another example, wiper seals may be used to accommodate greater manufacturing tolerances. In yet another example, the valve may have a single elastomeric component, or spring cap, which may combine the functionality of a number of components (e.g., a boot, spring, spring housing, and stem cap).

Abstract: Embodiments herein relate to systems and methods for thawing cells using magnetic particles, such as Curie-magnetic or Néel-magnetic particles. In an embodiment, a cell storage medium for cryopreservation is included. The cell storage medium can include a cryoprotective agent; and a plurality of particles comprising a magnetic material. In an embodiment, a method for thawing a frozen cell sample is included. The method can include obtaining a frozen cell sample comprising particles, the particles comprising a magnetic material and applying an alternating electromagnetic field to the frozen cell sample to induce heating of the magnetic material. Other embodiments are also included herein.

Abstract: Regulating cardiac activity may include pacing the patient's heart at a starting pacing rate and instigating an intrinsic heart beat search algorithm that includes pacing at a reduced rate for a period of time and capturing electrical signals representative of cardiac electrical activity while pacing at the reduced rate in order to determine a presence or absence of intrinsic heart beats. If intrinsic heart beats are not detected, the heart may be paced at a further reduced rate for a period of time. If intrinsic beats are detected, the heart may be paced again at the starting pacing rate. This may continue until intrinsic heart beats are detected or until a lower search rate limit is reached. Diagnostic data may be collected at each stage and transmitted to a display device for analysis by a physician or the like.