Patents by Inventor Caroline Barette

Caroline Barette has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic naphthoquinones derivatives for use in the treatment of cancers including Cushing disease
    Patent number: 11306063
    Abstract: The present invention concerns heterocyclic naphthoquinones derivatives for use in the treatment of Cushing disease and other cancers, in particular via the inhibition of Ubiquitin Specific Proteases (USP) 8 and/or 2.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: April 19, 2022
    Assignees: Commissariat a l'Energie Atomique et aux Energies Alternatives, Universite d'Aix Marseille
    Inventors: Marie-Odile Fauvarque, Magda Mortier, Catherine Pillet, Carmen Aguilar, Emmanuelle Soleilhac, Caroline Barette, Vincent Remusat, Thierry Terme, Patrice Vanelle
  • Pseudomonas aeruginosa inhibitor compounds
    Patent number: 10908153
    Abstract: The invention relates to a method of identifying molecules which inhibit the virulence machinery of Pseudomonas aeruginosa, to a device for identifying a molecule which inhibits the virulence machinery of Pseudomonas aeruginosa, to novel compounds which inhibit the virulence machinery of Pseudomonas aeruginosa, to compounds for use for preventing and/or treating a pathogenic infection caused by Pseudomonas aeruginosa and also to pharmaceutical compositions for preventing and/or treating a pathogenic infection caused by Pseudomonas aeruginosa.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: February 2, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES
    Inventors: Yung-Sing Wong, Sophie Ple, Ina Attree, Caroline Barette
  • Inhibitors of sterol metabolism for their use to accumulate triglycerides in microalgae, and methods thereof
    Patent number: 10844411
    Abstract: The invention relates to a method for accumulating triacylglycerols in microalgae by inhibiting the sterol metabolism, by incubating the microalgae with an inhibitor of sterol metabolism. The invention also relates to a method for producing fatty acids, biofuels, pharmaceutical or cosmetic compositions, and also food supplements, comprising a triacylglycerols accumulation step in microalgae according to the invention. Finally, the invention concerns the use of an inhibitor of sterol metabolism to accumulate triglycerides in microorganisms, and preferably microalgae.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: November 24, 2020
    Assignees: Commissariat A L'Energie Atomique Et Aux Energies Alternatives, Centre National De La Recherche Scientifique
    Inventors: Melissa Conte, Lina-Juana Dolch, Coline Mei, Caroline Barette, Dimitris Petroutsos, Denis Falconet, Juliette Jouhet, Fabrice Rebeille, Jean-Christophe Cintrat, Eric Marechal
  • Synthetic lethal drug combination for treating renal cell carcinoma
    Patent number: 10322133
    Abstract: The present invention pertains to a novel treatment of renal cell carcinoma and other a solid tumors which harbor a VHL inactivation, based on the combination of a first agent inhibiting a protein kinase CK2 (CK2) and a second agent inhibiting an Ataxia Telangiectasia Mutated (ATM) kinase.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: June 18, 2019
    Assignees: Commissariat a l'Energie Atomique et aux Energies Alternatives, Institut National de la Sante et de la Recherche Medicale
    Inventors: Sofia Giacosa, Catherine Pillet, Claude Cochet, Odile Filhol, Caroline Barette, Emmanuelle Soleilhac
  • Heterocyclic Naphthoquinones Derivatives for Use in the Treatment of Cancers Including Cushing Disease
    Publication number: 20190169136
    Abstract: The present invention concerns heterocyclic naphthoquinones derivatives for use in the treatment of Cushing disease and other cancers, in particular via the inhibition of Ubiquitin Specific Proteases (USP) 8 and/or 2.
    Type: Application
    Filed: August 7, 2017
    Publication date: June 6, 2019
    Applicants: Commissariat a l'Energie Atomique et aux Energies Alternatives, Universite Grenoble Alpes, Universite d'Aix Marseille
    Inventors: Marie-Odile Fauvarque, Magda Mortier, Catherine Pillet, Carmen Aguilar, Emmanuelle Soleilhac, Caroline Barette, Vincent Remusat, Thierry Terme, Patrice Vanelle
  • A Synthetic Lethal Drug Combination for Treating Renal Cell Carcinoma
    Publication number: 20180256587
    Abstract: The present invention pertains to a novel treatment of renal cell carcinoma and other a solid tumors which harbor a VHL inactivation, based on the combination of a first agent inhibiting a protein kinase CK2 (CK2) and a second agent inhibiting an Ataxia Telangiectasia Mutated (ATM) kinase.
    Type: Application
    Filed: September 21, 2016
    Publication date: September 13, 2018
    Applicants: Commissariat a l'Energie Atomique et aux Energies Alternatives, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Sofia Giacosa, Catherine Pillet, Claude Cochet, Odile Filhol, Caroline Barette, Emmanuelle Soleilhac
  • Pseudomonas Aeruginosa Inhibitor Compounds
    Publication number: 20180209969
    Abstract: The invention relates to a method of identifying molecules which inhibit the virulence machinery of Pseudomonas aeruginosa, to a device for identifying a molecule which inhibits the virulence machinery of Pseudomonas aeruginosa, to novel compounds which inhibit the virulence machinery of Pseudomonas aeruginosa, to compounds for use for preventing and/or treating a pathogenic infection caused by Pseudomonas aeruginosa and also to pharmaceutical compositions for preventing and/or treating a pathogenic infection caused by Pseudomonas aeruginosa.
    Type: Application
    Filed: July 12, 2016
    Publication date: July 26, 2018
    Applicants: Centre National de la Recherche Scientifique (CNRS), Commissariat A L'Energie Atomique et Aux Energies Alternatives
    Inventors: Yung-Sing Wong, Sophie Ple, Ina Attree, Caroline Barette
  • INHIBITORS OF STEROL METABOLISM FOR THEIR USE TO ACCUMULATE TRIGLYCERIDES IN MICROALGAE, AND METHODS THEREOF
    Publication number: 20160348138
    Abstract: The invention relates to a method for accumulating triacylglycerols in microalgae by inhibiting the sterol metabolism, N by incubating the microalgae with an inhibitor of sterol metabolism. The invention also relates to a method for producing fatty acids, biofuels, pharmaceutical or cosmetic compositions, and also food supplements, comprising a triacylglycerols accumulation step in microalgae according to the invention. Finally, the invention concerns the use of an inhibitor of sterol metabolism to accumulate triglycerides in microorganisms, and preferably microalgae.
    Type: Application
    Filed: January 27, 2015
    Publication date: December 1, 2016
    Inventors: Melissa Conte, Lina-Juana Dolch, Coline Mei, Caroline Barette, Dimitris Petroutsos, Denis Falconet, Juliette Jouhet, Fabrice Rebeille, Jean-Christophe Cintrat, Eric Marechal
  • Pyridocarbazole type compounds and applications thereof
    Patent number: 8604048
    Abstract: Pyridocarbazole-type compounds of formula (I): are provided as a medicament, and more particularly for application in anticancer chemotherapy. Also provided is a pharmaceutical composition with the compound and methods for preventing and/or treating neurodegenerative-type pathologies, such as Alzheimer's disease and schizophrenia, parasitoses, such as malaria, or glaucomas.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: December 10, 2013
    Assignees: Centre National de la Recherche Scientifique, Institut Curie, Commissariat a l'Energie Atomique et aux Energies Alternatives, Universite Paris Sud (Paris XI)
    Inventors: Laurence Lafanechere, Emilie Vassal, Caroline Barette, ChiHung Nguyen, Christian Rivalle, Renaud Prudent
  • PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF
    Publication number: 20120041017
    Abstract: Pyridocarbazole-type compounds of formula (I): are provided as a medicament, and more particularly for application in anticancer chemotherapy. Also provided is a pharmaceutical composition with the compound and methods for preventing and/or treating neurodegenerative-type pathologies, such as Alzheimer's disease and schizophrenia, parasitoses, such as malaria, or glaucomas.
    Type: Application
    Filed: February 19, 2010
    Publication date: February 16, 2012
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT A L ' ENERGIE ATOMIQUE ET AUX ENE ALT, INSTITUT CURIE
    Inventors: Laurence Lafanechere, Emilie Vassal, Caroline Barette, ChiHung Nguyen, Christian Rivalle, Renaud Prudent