Patents by Inventor Caroline Chandra Tjin

Caroline Chandra Tjin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small-molecule PI5P4K alpha/beta inhibitors and methods of treatment using same
    Patent number: 11773096
    Abstract: The present-disclosure relates to the discovery of novel 2-amino-dihydropteridinone compounds and analogues thereof, which are capable of inhibiting phosphatidylinositol phosphate kinases. In certain embodiments, the compounds of the present disclosure can be used to treat p53-null cancer in a subject. In other embodiments, the compounds of the present disclosure can be used to treat metabolic disorders in a subject, including but not limited to type 2 diabetes and/or obesity.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: October 3, 2023
    Assignee: YALE UNIVERSITY
    Inventors: Ya Ha, Jonathan Ellman, Song Chen, Caroline Chandra Tjin, Fabrizio Micheli, Agostino Cianciulli, Claudia Beato
  • Small-Molecule PI5P4K alpha/beta Inhibitors and Methods of Treatment Using Same
    Publication number: 20210292326
    Abstract: The present-disclosure relates to the discovery of novel 2-amino-dihydropteridinone compounds and analogues thereof, which are capable of inhibiting phosphatidylinositol phosphate kinases. In certain embodiments, the compounds of the present disclosure can be used to treat p53-null cancer in a subject. In other embodiments, the compounds of the present disclosure can be used to treat metabolic disorders in a subject, including but not limited to type 2 diabetes and/or obesity.
    Type: Application
    Filed: August 9, 2019
    Publication date: September 23, 2021
    Inventors: Ya Ha, Jonathan Ellman, Song Chen, Caroline Chandra Tjin, Fabrizio Micheli, Agostino Cianciulli, Claudia Beato