Patents by Inventor Caroline IMBERT
Caroline IMBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220233500Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: ApplicationFiled: April 4, 2022Publication date: July 28, 2022Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
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Patent number: 11291652Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: GrantFiled: June 30, 2020Date of Patent: April 5, 2022Assignee: JOURNEY MEDICAL CORPORATIONInventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
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Patent number: 11291651Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: GrantFiled: January 8, 2020Date of Patent: April 5, 2022Assignee: JOURNEY MEDICAL CORPORATIONInventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
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Publication number: 20210080467Abstract: Immune checkpoint inhibitors (ICI) have revolutionized therapy for advanced cancer, however many patients still do not respond to treatment. However, the efficacy and effectiveness of these therapies varies greatly across individual patients and among different tumour types. A substantial unmet need is thus the development of biomarkers of response to ICI, in order to identify, before initiation of treatment, which patients are likely to experience a response to and clinical benefit from such treatments. Here, the inventors analyzed SPHK1 mRNA in tumor biopsies by in situ hybridization using the RNAscope technology in a cohort of 32 patients suffering from metastatic melanoma. They showed that elevated expression of SPHK1, encoding sphingosine kinase 1 (SK1), which produces the oncometabolite sphingosine-1-phosphate (S1P) is associated with a poor survival in metastatic melanoma patients treated with to the well-known immune-checkpoint inhibitor anti-PD-1 antibody.Type: ApplicationFiled: February 20, 2019Publication date: March 18, 2021Inventors: Céline COLACIOS VIATGÉ, Caroline IMBERT, Bruno SEGUI, Nicolas MEYER, Laurence LAMANT-ROCHAIX, Thierry LEVADE, Nathalie ANDRIEU-ABADIE
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Publication number: 20210040215Abstract: The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen, the method comprising administering a pharmaceutically effective amount of a SK1 inhibitor to a subject in combination with the immune checkpoint inhibitor.Type: ApplicationFiled: September 29, 2020Publication date: February 11, 2021Inventors: Thierry LEVADE, Nicolas MEYER, Céline COLACIOS VIATGÉ, Caroline IMBERT, Nathalie ANDRIEU-ABADIE, Bruno SEGUI
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Patent number: 10822415Abstract: The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen, the method comprising administering a pharmaceutically effective amount of a SK1 inhibitor to a subject in combination with the immune checkpoint inhibitor.Type: GrantFiled: January 27, 2017Date of Patent: November 3, 2020Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉET DE LA RECHERCHE MÉDICALE), Université Toulouse III—Paul Sabatier, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSEInventors: Thierry Levade, Nicolas Meyer, Céline Colacios Viatgé, Caroline Imbert, Nathalie Andrieu-Abadie, Bruno Segui
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Publication number: 20200330430Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: ApplicationFiled: June 30, 2020Publication date: October 22, 2020Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
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Publication number: 20200138778Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: ApplicationFiled: January 8, 2020Publication date: May 7, 2020Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
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Patent number: 10548875Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: GrantFiled: December 28, 2018Date of Patent: February 4, 2020Assignee: Dermira, Inc.Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
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Patent number: 10543192Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: GrantFiled: June 1, 2018Date of Patent: January 28, 2020Assignee: Dermira, Inc.Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
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Publication number: 20190308994Abstract: Topical pharmaceutical formulations, and methods of treating inflammatory conditions with these formulations, are disclosed.Type: ApplicationFiled: June 25, 2019Publication date: October 10, 2019Applicant: Anacor Pharmaceuticals Inc.Inventors: Tejal Merchant, Dina Jean Coronado, Charles Edward Lee, Delphine Caroline Imbert, Sylvia Zarela Yep
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Publication number: 20190133999Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: ApplicationFiled: December 28, 2018Publication date: May 9, 2019Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
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Publication number: 20190031757Abstract: The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen, the method comprising administering a pharmaceutically effective amount of a SK1 inhibitor to a subject in combination with the immune checkpoint inhibitor.Type: ApplicationFiled: January 27, 2017Publication date: January 31, 2019Applicants: INSERM (Institut National De La Santé et de La Recherche Médicale, Université Paul Sabatier Toulouse III, Centre Hospitalier Universitaire de ToulouseInventors: Thierry LEVADE, Nicolas MEYER, Céline COLACIOS VIATGÉ, Caroline IMBERT, Nathalie ANDRIEU-ABADIE, Bruno SEGUI
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Patent number: 10092736Abstract: A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.Type: GrantFiled: May 4, 2016Date of Patent: October 9, 2018Assignee: Demira, Inc.Inventors: Hans Hofland, Delphine Caroline Imbert, Daniel O'Connell, Allen Pearson
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Publication number: 20180271833Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: ApplicationFiled: June 1, 2018Publication date: September 27, 2018Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
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Patent number: 10004717Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: GrantFiled: February 21, 2017Date of Patent: June 26, 2018Assignee: DERMIRA, INC.Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
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Publication number: 20170157088Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: ApplicationFiled: February 21, 2017Publication date: June 8, 2017Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
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Publication number: 20170152273Abstract: Topical pharmaceutical formulations, and methods of treating inflammatory conditions with these formulations, are disclosed.Type: ApplicationFiled: November 30, 2016Publication date: June 1, 2017Applicant: Anacor Pharmaceuticals Inc.Inventors: Tejal Merchant, Dina Jean Coronado, Charles Edward Lee, Delphine Caroline Imbert, Sylvia Zarela Yep
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Patent number: 9610278Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.Type: GrantFiled: January 7, 2016Date of Patent: April 4, 2017Assignee: Dermira, Inc.Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
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Patent number: 9440056Abstract: A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.Type: GrantFiled: September 29, 2015Date of Patent: September 13, 2016Assignee: Demira, Inc.Inventors: Hans Hofland, Delphine Caroline Imbert, Daniel O'Connell, Allen Pearson