Patents by Inventor Caroline IMBERT

Caroline IMBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220233500
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Application
    Filed: April 4, 2022
    Publication date: July 28, 2022
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
  • Patent number: 11291652
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: April 5, 2022
    Assignee: JOURNEY MEDICAL CORPORATION
    Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
  • Patent number: 11291651
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: April 5, 2022
    Assignee: JOURNEY MEDICAL CORPORATION
    Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
  • Publication number: 20210080467
    Abstract: Immune checkpoint inhibitors (ICI) have revolutionized therapy for advanced cancer, however many patients still do not respond to treatment. However, the efficacy and effectiveness of these therapies varies greatly across individual patients and among different tumour types. A substantial unmet need is thus the development of biomarkers of response to ICI, in order to identify, before initiation of treatment, which patients are likely to experience a response to and clinical benefit from such treatments. Here, the inventors analyzed SPHK1 mRNA in tumor biopsies by in situ hybridization using the RNAscope technology in a cohort of 32 patients suffering from metastatic melanoma. They showed that elevated expression of SPHK1, encoding sphingosine kinase 1 (SK1), which produces the oncometabolite sphingosine-1-phosphate (S1P) is associated with a poor survival in metastatic melanoma patients treated with to the well-known immune-checkpoint inhibitor anti-PD-1 antibody.
    Type: Application
    Filed: February 20, 2019
    Publication date: March 18, 2021
    Inventors: Céline COLACIOS VIATGÉ, Caroline IMBERT, Bruno SEGUI, Nicolas MEYER, Laurence LAMANT-ROCHAIX, Thierry LEVADE, Nathalie ANDRIEU-ABADIE
  • Publication number: 20210040215
    Abstract: The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen, the method comprising administering a pharmaceutically effective amount of a SK1 inhibitor to a subject in combination with the immune checkpoint inhibitor.
    Type: Application
    Filed: September 29, 2020
    Publication date: February 11, 2021
    Inventors: Thierry LEVADE, Nicolas MEYER, Céline COLACIOS VIATGÉ, Caroline IMBERT, Nathalie ANDRIEU-ABADIE, Bruno SEGUI
  • Patent number: 10822415
    Abstract: The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen, the method comprising administering a pharmaceutically effective amount of a SK1 inhibitor to a subject in combination with the immune checkpoint inhibitor.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: November 3, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉET DE LA RECHERCHE MÉDICALE), Université Toulouse III—Paul Sabatier, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
    Inventors: Thierry Levade, Nicolas Meyer, Céline Colacios Viatgé, Caroline Imbert, Nathalie Andrieu-Abadie, Bruno Segui
  • Publication number: 20200330430
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 22, 2020
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
  • Publication number: 20200138778
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Application
    Filed: January 8, 2020
    Publication date: May 7, 2020
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
  • Patent number: 10548875
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: February 4, 2020
    Assignee: Dermira, Inc.
    Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
  • Patent number: 10543192
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: January 28, 2020
    Assignee: Dermira, Inc.
    Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
  • Publication number: 20190308994
    Abstract: Topical pharmaceutical formulations, and methods of treating inflammatory conditions with these formulations, are disclosed.
    Type: Application
    Filed: June 25, 2019
    Publication date: October 10, 2019
    Applicant: Anacor Pharmaceuticals Inc.
    Inventors: Tejal Merchant, Dina Jean Coronado, Charles Edward Lee, Delphine Caroline Imbert, Sylvia Zarela Yep
  • Publication number: 20190133999
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Application
    Filed: December 28, 2018
    Publication date: May 9, 2019
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
  • Publication number: 20190031757
    Abstract: The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen, the method comprising administering a pharmaceutically effective amount of a SK1 inhibitor to a subject in combination with the immune checkpoint inhibitor.
    Type: Application
    Filed: January 27, 2017
    Publication date: January 31, 2019
    Applicants: INSERM (Institut National De La Santé et de La Recherche Médicale, Université Paul Sabatier Toulouse III, Centre Hospitalier Universitaire de Toulouse
    Inventors: Thierry LEVADE, Nicolas MEYER, Céline COLACIOS VIATGÉ, Caroline IMBERT, Nathalie ANDRIEU-ABADIE, Bruno SEGUI
  • Patent number: 10092736
    Abstract: A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: October 9, 2018
    Assignee: Demira, Inc.
    Inventors: Hans Hofland, Delphine Caroline Imbert, Daniel O'Connell, Allen Pearson
  • Publication number: 20180271833
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Application
    Filed: June 1, 2018
    Publication date: September 27, 2018
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
  • Patent number: 10004717
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: June 26, 2018
    Assignee: DERMIRA, INC.
    Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
  • Publication number: 20170157088
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Application
    Filed: February 21, 2017
    Publication date: June 8, 2017
    Inventors: John Allan STATLER, Anthony Adrian SHAW, Delphine Caroline IMBERT, Jennifer Leigh NELSON, Patricia ANDRES, Lisa Lynn McQUEEN, Stephan Xander Mattheus BOERRIGTER, Jon Gordon SELBO, Mark Christopher ANDRES
  • Publication number: 20170152273
    Abstract: Topical pharmaceutical formulations, and methods of treating inflammatory conditions with these formulations, are disclosed.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 1, 2017
    Applicant: Anacor Pharmaceuticals Inc.
    Inventors: Tejal Merchant, Dina Jean Coronado, Charles Edward Lee, Delphine Caroline Imbert, Sylvia Zarela Yep
  • Patent number: 9610278
    Abstract: Salts of glycopyrrolate, including solid forms and formulations such as topicals thereof, are disclosed. Methods of making glycopyrrolate salts, including formulations such as topicals thereof, and methods of treating hyperhidrosis with salts of glycopyrrolate, and formulations such as topicals thereof, are disclosed.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: April 4, 2017
    Assignee: Dermira, Inc.
    Inventors: John Allan Statler, Anthony Adrian Shaw, Delphine Caroline Imbert, Jennifer Leigh Nelson, Patricia Andres, Lisa Lynn McQueen, Stephan Xander Mattheus Boerrigter, Jon Gordon Selbo, Mark Christopher Andres
  • Patent number: 9440056
    Abstract: A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: September 13, 2016
    Assignee: Demira, Inc.
    Inventors: Hans Hofland, Delphine Caroline Imbert, Daniel O'Connell, Allen Pearson