Patents by Inventor Caroline Low

Caroline Low has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAP4K4 inhibitors
    Patent number: 11795169
    Abstract: This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There are also provided processes for producing compounds of the present invention and method of their use. In particular, the present invention relates to compounds of formula (I).
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 24, 2023
    Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: Michael Schneider, Gary Newton, Katie Chapman, Trevor Perrior, Ashley Jarvis, Caroline Low, Rehan Aqil, Martin Fisher, Melanie Bayford, Nicholas Chapman, Nicholas Martin, Tifelle Reisinger, Gabriel Negoita-Giras, Lorna R. Fieldler
  • 1H-PYRAZOLO[3,4-D]PYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PLATINUM-RESISTANT CANCER
    Publication number: 20230064189
    Abstract: The invention relates to compounds of formula (I) and related compounds and their use in the treatment of cancer, especially platinum resistant cancer. The invention also provides a treatment comprising administration of a compound of formula (I) and a platinum containing drug.
    Type: Application
    Filed: December 18, 2020
    Publication date: March 2, 2023
    Inventors: Caroline LOW, Albert JAXA-CHAMIEC, Paula CUNNEA, Hani GABRA, Evan STRONACH, Catherine TRALAU-STEWART
  • MAP4K4 INHIBITORS
    Publication number: 20200339583
    Abstract: This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There are also provided processes for producing compounds of the present invention and method of their use. In particular, the present invention relates to compounds of formula (I).
    Type: Application
    Filed: October 12, 2018
    Publication date: October 29, 2020
    Inventors: Michael SCHNEIDER, Gary NEWTON, Katie CHAPMAN, Trevor PERRIOR, Ashley JARVIS, Caroline LOW, Rehan AQIL, Martin FISHER, Melanie BAYFORD, Nicholas CHAPMAN, Nicholas MARTIN, Tifelle REISINGER, Gabriel NEGOITA-GIRAS, Lorna R. FIELDLER
  • Benzotriazepnes as gastrin and cholecystokinin receptor ligands
    Publication number: 20060003993
    Abstract: This invention relates to a compound of formula (I) wherein: W is N or N+—O?; and R1 to R5 are as defined in the description, for use for the treatment of gastrin related disorders.
    Type: Application
    Filed: November 12, 2002
    Publication date: January 5, 2006
    Applicant: James Black Foundation Limited
    Inventors: Iain McDonald, Ildiko Buck, Elaine Harper, Ian Linney, Michael Pether, Katherine Steel, Carol Austin, David Dunstone, Sarkis Kalindjian, Caroline Low, John Spencer, Paul Wright