Abstract: A clip device (1612) for hemostasis includes a clip having a plurality of arms (1640, 1650) each having a proximal end and a distal end, wherein each of the arms are spaced apart from each other when the clip is in an open position and adjacent to each other when the clip is in a closed position. At least one lumen (1643, 1653) is disposed within a first of the plurality of arms and spans from the proximal end to the distal end of the first arm. At least one outlet bore is formed in the distal end of the first arm. In use, the distal ends of the plurality of arms are adapted to engage tissue in the closed position, and a sclerosing agent is adapted to be delivered to tissue via the lumen and an outlet bore formed in the first arm. Such technique facilitates treatment of the underlying bleeding using a combination of mechanical and sclerotherapy approaches.

Abstract: A variety of stent arrangements are described in which multiple stents expand and coordinate to block the spaces between the struts of the outer stent to create a tubular stent not prone to tissue in-growth. One or more stents are selectively positioned within an outer stent such that the struts of the one or more stents at least partially fill the openings of the outer stent. Alternatively, the one or more stents may be permanently affixed to the outer stent to produce a stent arrangement in which the openings between the struts of the outer stent are blocked by the struts of the one or more stents.

Abstract: A clip device (1612) for hemostasis includes a clip having a plurality of arms (1640, 1650) each having a proximal end and a distal end, wherein each of the arms are spaced apart from each other when the clip is in an open position and adjacent to each other when the clip is in a closed position. At least one lumen (1643, 1653) is disposed within a first of the plurality of arms and spans from the proximal end to the distal end of the first arm. At least one outlet bore is formed in the distal end of the first arm. In use, the distal ends of the plurality of arms are adapted to engage tissue in the closed position, and a sclerosing agent is adapted to be delivered to tissue via the lumen and an outlet bore formed in the first arm. Such technique facilitates treatment of the underlying bleeding using a combination of mechanical and sclerotherapy approaches.

Abstract: A two-part extraction balloon and method of use is provided. The balloon catheter comprises a first balloon and a second balloon attached to an elongate catheter shaft near the distal end thereof. The first balloon has an inflated diameter that is larger than the inflated diameter of the second balloon, and in particular has an inflated working diameter range that is greater than the inflated working diameter range of the second balloon. Each of the balloons comprises an elastic or compliant material, and is separately inflatable via one of two inflation lumens extending through the catheter shaft. The larger first balloon is configured to engage and sweep calculi or debris through a relatively large bodily lumen, duct or passageway, whereas the smaller second balloon is configured to engage and sweep calculi or debris through a relatively small bodily lumen, duct or passageway.