Patents by Inventor Caroline Malai HULL

Caroline Malai HULL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNORESPONSIVE CELLS ARMOURED WITH SPATIOTEMPORALLY RESTRICTED ACTIVITY OF CYTOKINES OF THE IL-1 SUPERFAMILY
    Publication number: 20230000913
    Abstract: Provided herein are immunoresponsive cells having IL-1 superfamily activities with spatiotemporal restriction. The immunoresponsive cells can further express a protease for regulating the IL-1 superfamily activities, and a chimeric antigen receptor (CAR) or a parallel CAR. Also provided herein are methods of preparing the immunoresponsive cells and methods of directing T cell mediated immune response using the immunoresponsive cells.
    Type: Application
    Filed: August 13, 2020
    Publication date: January 5, 2023
    Inventors: John MAHER, Caroline Malai HULL