Patents by Inventor Caroline Proulx

Caroline Proulx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azapeptides as CD36 binding compounds
    Patent number: 9708370
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B ??I.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: July 18, 2017
    Assignees: VALORISATION-RECHERCHE, LIMITED PARTNERSHIP, VALORISATION HSJ, LIMITED PARTNERSHIP
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • AZAPEPTIDES AS CD36 BINDING COMPOUNDS
    Publication number: 20150329591
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B
    Type: Application
    Filed: July 28, 2015
    Publication date: November 19, 2015
    Inventors: Huy ONG, Sylvain CHEMTOB, William LUBELL, Florian SENNLAUB, Damien BOEGLIN, Caroline PROULX, Zohreh SAJJADI, David SABATINO
  • Azapeptides as CD36 binding compounds
    Patent number: 9115171
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B??I.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 25, 2015
    Assignees: VALORISATION-RECHERCHE, LIMITED PARTNERSHIP, VALORISATION HSJ, LIMITED PARTNERSHIP
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • Peptidomimetics comprising N-amino cyclic urea residues and uses thereof
    Patent number: 8993515
    Abstract: Novel peptidomimetics comprising N-amino cyclic urea residues are disclosed. Use of such peptidomimetics for modulating the activity of CD36 or IL-1 receptor in a cell, and for treating CD36- or IL-1-related disease, disorder or condition is also described.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: March 31, 2015
    Assignees: Valorisation-Recherche, Limited Partnership, RSEM, Limited Partnership
    Inventors: William D. Lubell, Sylvain Chemtob, Huy Ong, Robert Hopewell, Caroline Proulx, Kim Beauregard, Yesica Garcia-Ramos, Ngoc-Duc Doan
  • PEPTIDOMIMETICS COMPRISING N-AMINO CYCLIC UREA RESIDUES AND USES THEREOF
    Publication number: 20140024606
    Abstract: Novel peptidomimetics comprising N-amino cyclic urea residues are disclosed.
    Type: Application
    Filed: June 5, 2013
    Publication date: January 23, 2014
    Inventors: WILLIAM D. LUBELL, SYLVAIN CHEMTOB, HUY ONG, ROBERT HOPEWELL, CAROLINE PROULX, KIM BEAUREGARD, YESICA GARCIA-RAMOS, NGOC-DUC DOAN
  • AZAPEPTIDES AS CD36 BINDING COMPOUNDS
    Publication number: 20130203686
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b—B??I.
    Type: Application
    Filed: March 14, 2013
    Publication date: August 8, 2013
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • Azapeptides as CD36 binding compounds
    Patent number: 8435954
    Abstract: An azapeptide derivative of growth hormone releasing peptide (GHRP) of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B which binds to CD 36.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: May 7, 2013
    Assignees: Valorisation-Recherche, Limited Partnership, Valorisation HSJ, Limited Partnership
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • Succinate salt of 2-((4-(1-methyl-4-pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)quinoline
    Patent number: 8283471
    Abstract: The present invention relates to a succinate salt of 2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)quinoline, and to a method for treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal the succinate salt. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and the succinate salt.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: October 9, 2012
    Assignee: Pfizer, Inc.
    Inventors: Caroline Proulx-Lafrance, Patrick Robert Verhoest
  • Pyrazolo[3,4-d]pyrimidine compounds
    Patent number: 7964607
    Abstract: The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R, R1, R2 and R3 are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: June 21, 2011
    Assignee: Pfizer Inc.
    Inventors: Patrick Robert Verhoest, Caroline Proulx-Lafrance
  • AZAPEPTIDES AS CD36 BINDING COMPOUNDS
    Publication number: 20100210566
    Abstract: An azapeptide derivative of growth hormone releasing peptide (GHRP) of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B which binds to CD 36.
    Type: Application
    Filed: June 18, 2008
    Publication date: August 19, 2010
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • SUCCINATE SALT OF 2-((4-(1-METHYL-4-PYRIDIN-4-YL)-1H-PYRAZOL-3-YL)PHENOXY)METHYL)QUINOLINE
    Publication number: 20100063089
    Abstract: The present invention relates to a succinate salt of 2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)quinoline, and to a method for treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal the succinate salt. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and the succinate salt.
    Type: Application
    Filed: December 3, 2007
    Publication date: March 11, 2010
    Inventors: Caroline Proulx-Lafrance, Patrick Robert Verhoest
  • AMINO-HETEROCYCLIC COMPOUNDS
    Publication number: 20090030003
    Abstract: The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R, R1, R2 and R3 are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided.
    Type: Application
    Filed: May 9, 2008
    Publication date: January 29, 2009
    Inventors: Patrick R. Verhoest, Caroline Proulx-Lafrance