Patents by Inventor Caroline Robert

Caroline Robert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250012805
    Abstract: The present invention relates to a method of predicting, assessing or monitoring the sensitivity of a subject having a cancer to an immunotherapy, preferably to an immunotherapy combining at least two immunotherapeutic agents, and to corresponding kits and uses thereof. The method of predicting, assessing or monitoring the sensitivity of a subject having a tumor to an immunotherapy typically comprises a step of assessing, before any immunotherapeutic treatment step in the subject, the presence of CD4+CD25highCD39high T cells in a tumor sample of the subject, the presence of CD4+CD25highCD39high T cells in the tumor sample of the subject being indicative of sensitivity of the subject to the immunotherapy, and the absence of CD4+CD25highCD39high T cells in the tumor sample of the subject being indicative of resistance of the subject to the immunotherapy.
    Type: Application
    Filed: November 10, 2022
    Publication date: January 9, 2025
    Inventors: LAMBROS TSELIKAS, FRANÇOIS-XAVIER DANLOS, DELPHINE BREDEL, SANDRINE SUSINI, MÉLODIE BONVALET, SÉVERINE MOURAUD, CAROLINE ROBERT, AURÉLIEN MARABELLE
  • Publication number: 20240393340
    Abstract: The present invention relates to a method of evaluating the sensitivity or resistance of a cancer cell to an antitumoral therapeutic treatment. It further relates to the treatment of a cancer with an inhibitor of the eiF4F complex used for the sensitisation of said cancer to an antitumoral therapeutic treatment.
    Type: Application
    Filed: July 31, 2024
    Publication date: November 28, 2024
    Inventors: CAROLINE ROBERT, LISE BOUSSEMART, ISABELLE GIRAULT, STÉPHAN VAGNER
  • Publication number: 20180267535
    Abstract: The invention concerns an architecture for a driving assistance system with conditional automation capable of controlling an automatic emergency stop of a vehicle, comprising: a set (2) of sensors of at least three different technologies for observing an area in front of a vehicle; a main computer (10) capable of receiving, via a first upstream data communication network, information from said set (2) of sensors, and of transmitting commands, via a first downstream communication network, to a first computer (3) of an engine control system, to a second computer (4) of a braking system and to a third computer (5) of a steering control system: a backup computer (11) capable of receiving, via a second upstream data communication network, information from said set of sensors in case of a failure relative to the main computer (10); a main power supply source linked to each computer; and a backup power supply source.
    Type: Application
    Filed: January 4, 2016
    Publication date: September 20, 2018
    Applicant: VALEO Schalter und Sensoren GmbH
    Inventors: Caroline Robert, Vanessa Picron, Michel Leeman
  • Patent number: 9810692
    Abstract: The present invention relates to a method of assessing, predicting or monitoring the sensitivity of a subject having a tumor or cancer to an immunotherapeutic molecule acting on the subject's T cells, to a method of selecting an appropriate treatment of cancer, to a method of screening or identifying a compound suitable for improving the treatment of a cancer, and to the use of corresponding kits. The method of predicting or monitoring the sensitivity of a subject having a tumor to an immunotherapeutic molecule acting on the subject's T cells typically comprises a step a) of determining, in a biological sample from said subject, the expression level of soluble CD25 (sCD25) and, when the expression level is determined, a step b) of comparing at least said expression level to a reference expression level, thereby assessing whether the subject having a tumor is responsive or resistant to the immunotherapeutic molecule.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: November 7, 2017
    Assignee: INSTITUT GUSTAVE ROUSSY
    Inventors: Dalil Hannani, Laurence Zitvogel, Caroline Robert, Nathalie Chaput-Gras
  • Patent number: 9524438
    Abstract: The invention relates to a vehicle (10) with at least one camera (16), by means of which at least one image area of a surrounding of the vehicle (10) is capturable, the image area comprising a plurality of pixels and being arranged obliquely above a vehicle front as viewed in the direction of travel of the vehicle (10), and with a tunnel detection device (44) designed for determining an average brightness of the at least one image area. The tunnel detection device (44) comprises a device (46) for feature or edge detection, by means of which differences in the brightness of pixels differing from each other are capturable and thus features characterized by abrupt changes in brightness are detectable in the at least one image area. Moreover, the invention relates to a method for operating a camera arrangement for a vehicle (10).
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: December 20, 2016
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Brouk Wedajo, Yan Quelquejay, Samia Ahiad, Caroline Robert
  • Publication number: 20160116480
    Abstract: The present invention relates to a method of evaluating the sensitivity or resistance of a cancer cell to an antitumoral therapeutic treatment. It further relates to the treatment of a cancer with an inhibitor of the eiF4F complex used for the sensitisation of said cancer to an antitumoral therapeutic treatment.
    Type: Application
    Filed: May 13, 2014
    Publication date: April 28, 2016
    Inventors: CAROLINE ROBERT, LISE BOUSSEMART, ISABELLE GIRAULT, STÉPHAN VAGNER
  • Patent number: 9230189
    Abstract: The invention relates to a method of raindrop detection on a vehicle windscreen by capturing images using a camera which is at least focused on the windscreen, including a step of detecting edges (102) in a research area of said captured images, characterized in that said method of raindrop detection comprises a rejection step (103) in which edges that are uncharacteristic with respect to a raindrop are rejected. This invention also relates to an associated driving assistance device.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: January 5, 2016
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Caroline Robert, Samia Ahiad
  • Patent number: 9205810
    Abstract: The invention relates to a method of fog and raindrop detection on a windscreen (200), comprising a raindrop detection application (201) and a fog detection application (202), characterized in that said fog detection application (202) comprises a step (202b) in which an indication of the presence of raindrop is detected, said indication of raindrop presence triggering a switch from said fog detection application (202) to said raindrop detection application (201).
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: December 8, 2015
    Assignee: VALEO Schalter und Sensoren GmbH
    Inventors: Caroline Robert, Samia Ahiad
  • Publication number: 20150310304
    Abstract: The invention relates to a method of raindrop detection on a vehicle windscreen by capturing images using a camera which is at least focused on the windscreen, including a step of detecting edges (102) in a research area of said captured images, characterized in that said method of raindrop detection comprises a rejection step (103) in which edges that are uncharacteristic with respect to a raindrop are rejected. This invention also relates to an associated driving assistance device.
    Type: Application
    Filed: March 4, 2010
    Publication date: October 29, 2015
    Applicant: VALEO SCHALTER UND SENSOREN GMBH
    Inventors: Caroline Robert, Samia Ahiad, Xiyuan Zhang
  • Publication number: 20150268243
    Abstract: The present invention relates to a method of assessing, predicting or monitoring the sensitivity of a subject having a tumor or cancer to an immunotherapeutic molecule acting on the subject's T cells, to a method of selecting an appropriate treatment of cancer, to a method of screening or identifying a compound suitable for improving the treatment of a cancer, and to the use of corresponding kits. The method of predicting or monitoring the sensitivity of a subject having a tumor to an immunotherapeutic molecule acting on the subject's T cells typically comprises a step a) of determining, in a biological sample from said subject, the expression level of soluble CD25 (sCD25) and, when the expression level is determined, a step b) of comparing at least said expression level to a reference expression level thereby assessing whether the subject having a tumor is responsive or resistant to the immunotherapeutic molecule.
    Type: Application
    Filed: October 25, 2013
    Publication date: September 24, 2015
    Inventors: Dalil Hannani, Laurence Zitvogel, Caroline Robert, Nathalie Chaput-Gras
  • Patent number: 9081263
    Abstract: A camera set up for fitting on board a motor vehicle. The camera has an electronic sensor, a multifocal, particularly bifocal optical device, an optical lens focused in long-range field, the multifocal optical device and the optical lens being set up to be able to form a first image (IM1) on the sensor, focused in long-range field, and a second image (IM2) focused in close-range field, these first and second images extending into respective distinct regions of the sensor.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: July 14, 2015
    Assignee: Valeo Vision
    Inventors: Alice Mulin, Caroline Robert
  • Publication number: 20140347487
    Abstract: The invention relates to a method and a camera assembly for detecting raindrops (28) on a windscreen of a vehicle, in which at least one image (14) is captured by a camera (12), at least one reference object (20) is identified in a first image (18) captured by the camera (12) and the at least one identified object (20) is at least partially superimposed to at least one object extracted from a second image (16) captured by the camera. Raindrop (28) detection is performed within the second image (16).
    Type: Application
    Filed: September 7, 2011
    Publication date: November 27, 2014
    Applicant: VALEO SCHALTER UND SENSOREN GMBH
    Inventors: Samia Ahiad, Caroline Robert
  • Publication number: 20140184798
    Abstract: The invention relates to a vehicle (10) with at least one camera (16), by means of which at least one image area of a surrounding of the vehicle (10) is capturable, the image area comprising a plurality of pixels and being arranged obliquely above a vehicle front as viewed in the direction of travel of the vehicle (10), and with a tunnel detection device (44) designed for determining an average brightness of the at least one image area. The tunnel detection device (44) comprises a device (46) for feature or edge detection, by means of which differences in the brightness of pixels differing from each other are capturable and thus features characterized by abrupt changes in brightness are detectable in the at least one image area. Moreover, the invention relates to a method for operating a camera arrangement for a vehicle (10).
    Type: Application
    Filed: May 16, 2011
    Publication date: July 3, 2014
    Applicant: VALEO SCHALTER UND SENSOREN GMBH
    Inventors: Brouk Wedajo, Yan Quelquejay, Samia Ahiad, Caroline Robert
  • Patent number: 8757853
    Abstract: A system and method for controlling a vehicle headlamp, the headlamp being equipped with an automatic switching unit between high beam and low beam lighting modes and with a bending light function (DBL). The method comprises a step of making the bending light function (DBL) change from a first active state to a second state for detecting a combination of conditions comprising an active state of the automatic switching unit between high beam and low beam lighting modes and an active state of the high beam lighting mode.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: June 24, 2014
    Assignee: Valeo Vision
    Inventors: Caroline Robert, Patrick Bonhoure
  • Patent number: 8738235
    Abstract: A detection method, system and device for a motor vehicle (V1). The method, system and device uses at least one camera which has a predetermined field of vision. The method includes the following steps: receiving information which is representative of a driving state associated with the vehicle; and modifying the field of vision of the camera, and in particular its orientation, according to the information.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: May 27, 2014
    Assignee: Valeo Vision
    Inventors: Anne Laliron, Caroline Robert
  • Publication number: 20130039544
    Abstract: The invention relates to a method of fog and raindrop detection on a windscreen (200), comprising a raindrop detection application (201) and a fog detection application (202), characterized in that said fog detection application (202) comprises a step (202b) in which an indication of the presence of raindrop is detected, said indication of raindrop presence triggering a switch from said fog detection application (202) to said raindrop detection application (201).
    Type: Application
    Filed: March 4, 2010
    Publication date: February 14, 2013
    Applicant: Valeo Schalter und Sensoren GmbH
    Inventors: Caroline Robert, Samia Ahiad, Xiyuan Zhang
  • Patent number: 8305431
    Abstract: A system and method to support the driving of a motor vehicle comprising in particular a system capable of capturing images, wherein the system for capturing images comprises a stereoscopic image capturing system having at least a first camera and a second camera, with the first camera presenting a field of vision) greater than the field of vision of the second camera, and with the stereoscopic system thereby conferring a degree of multifunctionality to the device supporting the driving of the vehicle.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: November 6, 2012
    Assignee: Valeo Vision
    Inventors: Caroline Robert, Julien Rebut
  • Publication number: 20110216197
    Abstract: A camera set up for fitting on board a motor vehicle. The camera has an electronic sensor, a multifocal, particularly bifocal optical device, an optical lens focused in long-range field, the multifocal optical device and the optical lens being set up to be able to form a first image (IM1) on the sensor, focused in long-range field, and a second image (IM2) focused in close-range field, these first and second images extending into respective distinct regions of the sensor.
    Type: Application
    Filed: March 4, 2011
    Publication date: September 8, 2011
    Applicant: VALEO VISION
    Inventors: Alice MULIN, Caroline ROBERT
  • Publication number: 20110184610
    Abstract: A detection method, system and device for a motor vehicle (V1). The method system and device uses at least one camera which has a predetermined field of vision. The method includes the following steps: receiving information which is representative of a driving state associated with the vehicle; and modifying the field of vision of the camera, and in particular its orientation, according to the information.
    Type: Application
    Filed: January 20, 2011
    Publication date: July 28, 2011
    Applicant: VALEO VISION
    Inventors: Anne LALIRON, Caroline ROBERT
  • Patent number: 7920250
    Abstract: A process for the detection from a vehicle of a visibility interference phenomenon, comprising the following steps: the emission of a beam of light to illuminate the rear of the vehicle, the beam of light being emitted into a field of vision of a camera mounted in the vehicle, and the determination of a presence and the nature of a visibility interference phenomenon on the basis of at least one image captured by the camera.
    Type: Grant
    Filed: July 29, 2008
    Date of Patent: April 5, 2011
    Assignee: Valeo Vision
    Inventors: Caroline Robert, Joël Leleve, David Hue