Patents by Inventor Caroline Robert
Caroline Robert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250012805Abstract: The present invention relates to a method of predicting, assessing or monitoring the sensitivity of a subject having a cancer to an immunotherapy, preferably to an immunotherapy combining at least two immunotherapeutic agents, and to corresponding kits and uses thereof. The method of predicting, assessing or monitoring the sensitivity of a subject having a tumor to an immunotherapy typically comprises a step of assessing, before any immunotherapeutic treatment step in the subject, the presence of CD4+CD25highCD39high T cells in a tumor sample of the subject, the presence of CD4+CD25highCD39high T cells in the tumor sample of the subject being indicative of sensitivity of the subject to the immunotherapy, and the absence of CD4+CD25highCD39high T cells in the tumor sample of the subject being indicative of resistance of the subject to the immunotherapy.Type: ApplicationFiled: November 10, 2022Publication date: January 9, 2025Inventors: LAMBROS TSELIKAS, FRANÇOIS-XAVIER DANLOS, DELPHINE BREDEL, SANDRINE SUSINI, MÉLODIE BONVALET, SÉVERINE MOURAUD, CAROLINE ROBERT, AURÉLIEN MARABELLE
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Publication number: 20240393340Abstract: The present invention relates to a method of evaluating the sensitivity or resistance of a cancer cell to an antitumoral therapeutic treatment. It further relates to the treatment of a cancer with an inhibitor of the eiF4F complex used for the sensitisation of said cancer to an antitumoral therapeutic treatment.Type: ApplicationFiled: July 31, 2024Publication date: November 28, 2024Inventors: CAROLINE ROBERT, LISE BOUSSEMART, ISABELLE GIRAULT, STÉPHAN VAGNER
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Publication number: 20180267535Abstract: The invention concerns an architecture for a driving assistance system with conditional automation capable of controlling an automatic emergency stop of a vehicle, comprising: a set (2) of sensors of at least three different technologies for observing an area in front of a vehicle; a main computer (10) capable of receiving, via a first upstream data communication network, information from said set (2) of sensors, and of transmitting commands, via a first downstream communication network, to a first computer (3) of an engine control system, to a second computer (4) of a braking system and to a third computer (5) of a steering control system: a backup computer (11) capable of receiving, via a second upstream data communication network, information from said set of sensors in case of a failure relative to the main computer (10); a main power supply source linked to each computer; and a backup power supply source.Type: ApplicationFiled: January 4, 2016Publication date: September 20, 2018Applicant: VALEO Schalter und Sensoren GmbHInventors: Caroline Robert, Vanessa Picron, Michel Leeman
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Patent number: 9810692Abstract: The present invention relates to a method of assessing, predicting or monitoring the sensitivity of a subject having a tumor or cancer to an immunotherapeutic molecule acting on the subject's T cells, to a method of selecting an appropriate treatment of cancer, to a method of screening or identifying a compound suitable for improving the treatment of a cancer, and to the use of corresponding kits. The method of predicting or monitoring the sensitivity of a subject having a tumor to an immunotherapeutic molecule acting on the subject's T cells typically comprises a step a) of determining, in a biological sample from said subject, the expression level of soluble CD25 (sCD25) and, when the expression level is determined, a step b) of comparing at least said expression level to a reference expression level, thereby assessing whether the subject having a tumor is responsive or resistant to the immunotherapeutic molecule.Type: GrantFiled: October 25, 2013Date of Patent: November 7, 2017Assignee: INSTITUT GUSTAVE ROUSSYInventors: Dalil Hannani, Laurence Zitvogel, Caroline Robert, Nathalie Chaput-Gras
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Patent number: 9524438Abstract: The invention relates to a vehicle (10) with at least one camera (16), by means of which at least one image area of a surrounding of the vehicle (10) is capturable, the image area comprising a plurality of pixels and being arranged obliquely above a vehicle front as viewed in the direction of travel of the vehicle (10), and with a tunnel detection device (44) designed for determining an average brightness of the at least one image area. The tunnel detection device (44) comprises a device (46) for feature or edge detection, by means of which differences in the brightness of pixels differing from each other are capturable and thus features characterized by abrupt changes in brightness are detectable in the at least one image area. Moreover, the invention relates to a method for operating a camera arrangement for a vehicle (10).Type: GrantFiled: May 16, 2011Date of Patent: December 20, 2016Assignee: VALEO Schalter und Sensoren GmbHInventors: Brouk Wedajo, Yan Quelquejay, Samia Ahiad, Caroline Robert
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Publication number: 20160116480Abstract: The present invention relates to a method of evaluating the sensitivity or resistance of a cancer cell to an antitumoral therapeutic treatment. It further relates to the treatment of a cancer with an inhibitor of the eiF4F complex used for the sensitisation of said cancer to an antitumoral therapeutic treatment.Type: ApplicationFiled: May 13, 2014Publication date: April 28, 2016Inventors: CAROLINE ROBERT, LISE BOUSSEMART, ISABELLE GIRAULT, STÉPHAN VAGNER
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Patent number: 9230189Abstract: The invention relates to a method of raindrop detection on a vehicle windscreen by capturing images using a camera which is at least focused on the windscreen, including a step of detecting edges (102) in a research area of said captured images, characterized in that said method of raindrop detection comprises a rejection step (103) in which edges that are uncharacteristic with respect to a raindrop are rejected. This invention also relates to an associated driving assistance device.Type: GrantFiled: March 4, 2010Date of Patent: January 5, 2016Assignee: VALEO Schalter und Sensoren GmbHInventors: Caroline Robert, Samia Ahiad
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Patent number: 9205810Abstract: The invention relates to a method of fog and raindrop detection on a windscreen (200), comprising a raindrop detection application (201) and a fog detection application (202), characterized in that said fog detection application (202) comprises a step (202b) in which an indication of the presence of raindrop is detected, said indication of raindrop presence triggering a switch from said fog detection application (202) to said raindrop detection application (201).Type: GrantFiled: March 4, 2010Date of Patent: December 8, 2015Assignee: VALEO Schalter und Sensoren GmbHInventors: Caroline Robert, Samia Ahiad
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Publication number: 20150310304Abstract: The invention relates to a method of raindrop detection on a vehicle windscreen by capturing images using a camera which is at least focused on the windscreen, including a step of detecting edges (102) in a research area of said captured images, characterized in that said method of raindrop detection comprises a rejection step (103) in which edges that are uncharacteristic with respect to a raindrop are rejected. This invention also relates to an associated driving assistance device.Type: ApplicationFiled: March 4, 2010Publication date: October 29, 2015Applicant: VALEO SCHALTER UND SENSOREN GMBHInventors: Caroline Robert, Samia Ahiad, Xiyuan Zhang
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Publication number: 20150268243Abstract: The present invention relates to a method of assessing, predicting or monitoring the sensitivity of a subject having a tumor or cancer to an immunotherapeutic molecule acting on the subject's T cells, to a method of selecting an appropriate treatment of cancer, to a method of screening or identifying a compound suitable for improving the treatment of a cancer, and to the use of corresponding kits. The method of predicting or monitoring the sensitivity of a subject having a tumor to an immunotherapeutic molecule acting on the subject's T cells typically comprises a step a) of determining, in a biological sample from said subject, the expression level of soluble CD25 (sCD25) and, when the expression level is determined, a step b) of comparing at least said expression level to a reference expression level thereby assessing whether the subject having a tumor is responsive or resistant to the immunotherapeutic molecule.Type: ApplicationFiled: October 25, 2013Publication date: September 24, 2015Inventors: Dalil Hannani, Laurence Zitvogel, Caroline Robert, Nathalie Chaput-Gras
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Patent number: 9081263Abstract: A camera set up for fitting on board a motor vehicle. The camera has an electronic sensor, a multifocal, particularly bifocal optical device, an optical lens focused in long-range field, the multifocal optical device and the optical lens being set up to be able to form a first image (IM1) on the sensor, focused in long-range field, and a second image (IM2) focused in close-range field, these first and second images extending into respective distinct regions of the sensor.Type: GrantFiled: March 4, 2011Date of Patent: July 14, 2015Assignee: Valeo VisionInventors: Alice Mulin, Caroline Robert
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Publication number: 20140347487Abstract: The invention relates to a method and a camera assembly for detecting raindrops (28) on a windscreen of a vehicle, in which at least one image (14) is captured by a camera (12), at least one reference object (20) is identified in a first image (18) captured by the camera (12) and the at least one identified object (20) is at least partially superimposed to at least one object extracted from a second image (16) captured by the camera. Raindrop (28) detection is performed within the second image (16).Type: ApplicationFiled: September 7, 2011Publication date: November 27, 2014Applicant: VALEO SCHALTER UND SENSOREN GMBHInventors: Samia Ahiad, Caroline Robert
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Publication number: 20140184798Abstract: The invention relates to a vehicle (10) with at least one camera (16), by means of which at least one image area of a surrounding of the vehicle (10) is capturable, the image area comprising a plurality of pixels and being arranged obliquely above a vehicle front as viewed in the direction of travel of the vehicle (10), and with a tunnel detection device (44) designed for determining an average brightness of the at least one image area. The tunnel detection device (44) comprises a device (46) for feature or edge detection, by means of which differences in the brightness of pixels differing from each other are capturable and thus features characterized by abrupt changes in brightness are detectable in the at least one image area. Moreover, the invention relates to a method for operating a camera arrangement for a vehicle (10).Type: ApplicationFiled: May 16, 2011Publication date: July 3, 2014Applicant: VALEO SCHALTER UND SENSOREN GMBHInventors: Brouk Wedajo, Yan Quelquejay, Samia Ahiad, Caroline Robert
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Patent number: 8757853Abstract: A system and method for controlling a vehicle headlamp, the headlamp being equipped with an automatic switching unit between high beam and low beam lighting modes and with a bending light function (DBL). The method comprises a step of making the bending light function (DBL) change from a first active state to a second state for detecting a combination of conditions comprising an active state of the automatic switching unit between high beam and low beam lighting modes and an active state of the high beam lighting mode.Type: GrantFiled: September 29, 2010Date of Patent: June 24, 2014Assignee: Valeo VisionInventors: Caroline Robert, Patrick Bonhoure
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Patent number: 8738235Abstract: A detection method, system and device for a motor vehicle (V1). The method, system and device uses at least one camera which has a predetermined field of vision. The method includes the following steps: receiving information which is representative of a driving state associated with the vehicle; and modifying the field of vision of the camera, and in particular its orientation, according to the information.Type: GrantFiled: January 20, 2011Date of Patent: May 27, 2014Assignee: Valeo VisionInventors: Anne Laliron, Caroline Robert
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Publication number: 20130039544Abstract: The invention relates to a method of fog and raindrop detection on a windscreen (200), comprising a raindrop detection application (201) and a fog detection application (202), characterized in that said fog detection application (202) comprises a step (202b) in which an indication of the presence of raindrop is detected, said indication of raindrop presence triggering a switch from said fog detection application (202) to said raindrop detection application (201).Type: ApplicationFiled: March 4, 2010Publication date: February 14, 2013Applicant: Valeo Schalter und Sensoren GmbHInventors: Caroline Robert, Samia Ahiad, Xiyuan Zhang
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Patent number: 8305431Abstract: A system and method to support the driving of a motor vehicle comprising in particular a system capable of capturing images, wherein the system for capturing images comprises a stereoscopic image capturing system having at least a first camera and a second camera, with the first camera presenting a field of vision) greater than the field of vision of the second camera, and with the stereoscopic system thereby conferring a degree of multifunctionality to the device supporting the driving of the vehicle.Type: GrantFiled: September 17, 2008Date of Patent: November 6, 2012Assignee: Valeo VisionInventors: Caroline Robert, Julien Rebut
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Publication number: 20110216197Abstract: A camera set up for fitting on board a motor vehicle. The camera has an electronic sensor, a multifocal, particularly bifocal optical device, an optical lens focused in long-range field, the multifocal optical device and the optical lens being set up to be able to form a first image (IM1) on the sensor, focused in long-range field, and a second image (IM2) focused in close-range field, these first and second images extending into respective distinct regions of the sensor.Type: ApplicationFiled: March 4, 2011Publication date: September 8, 2011Applicant: VALEO VISIONInventors: Alice MULIN, Caroline ROBERT
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Publication number: 20110184610Abstract: A detection method, system and device for a motor vehicle (V1). The method system and device uses at least one camera which has a predetermined field of vision. The method includes the following steps: receiving information which is representative of a driving state associated with the vehicle; and modifying the field of vision of the camera, and in particular its orientation, according to the information.Type: ApplicationFiled: January 20, 2011Publication date: July 28, 2011Applicant: VALEO VISIONInventors: Anne LALIRON, Caroline ROBERT
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Patent number: 7920250Abstract: A process for the detection from a vehicle of a visibility interference phenomenon, comprising the following steps: the emission of a beam of light to illuminate the rear of the vehicle, the beam of light being emitted into a field of vision of a camera mounted in the vehicle, and the determination of a presence and the nature of a visibility interference phenomenon on the basis of at least one image captured by the camera.Type: GrantFiled: July 29, 2008Date of Patent: April 5, 2011Assignee: Valeo VisionInventors: Caroline Robert, Joël Leleve, David Hue