Patents by Inventor Caroline Whitworth

Caroline Whitworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
    Publication number: 20100179139
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.
    Type: Application
    Filed: May 29, 2008
    Publication date: July 15, 2010
    Inventors: Paul Bamborough, Michael David Barker, Sebastien Andre Campos, Richard Peter Charles Cousins, Paul Faulder, Heather Hobbs, Duncan Stuart Holmes, Michael John Johnston, John Liddle, Jeremy John Payne, John Martin Pritchard, Caroline Whitworth
  • PYRROLO[2,3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS 1KK2 INHIBITORS
    Publication number: 20100035917
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to Formula (1) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular 1KK2 activity.
    Type: Application
    Filed: September 20, 2007
    Publication date: February 11, 2010
    Inventors: Paul Bamborough, Michael David Barker, Sebastien Andre Campos, Richard Peter Charles Cousins, Paul Faulder, Heather Hobbs, Duncan Stuart Holmes, Michael John Johnston, John Liddle, Jeremy John Payne, John Martin Pritchard, Caroline Whitworth
  • Pyrrolidine derivatives as factor Xa inhibitors
    Patent number: 7517879
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: April 14, 2009
    Assignee: Glaxo Group Limited
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • Pyrrolidine derivatives as factor Xa inhibitors
    Patent number: 7429587
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: September 30, 2008
    Assignee: Glaxo Group Limited
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • NOVEL COMPOUNDS
    Publication number: 20080176891
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.
    Type: Application
    Filed: September 20, 2007
    Publication date: July 24, 2008
    Inventors: Paul Bamborough, Michael David Barker, Sebastien Andre Campos, Richard Peter Charles Cousins, Paul Faulder, Heather Hobbs, Duncan Stuart Holmes, Michael John Johnston, John Liddle, Jeremy John Payne, John Martin Pritchard, Caroline Whitworth
  • NOVEL COMPOUNDS
    Publication number: 20080146606
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.
    Type: Application
    Filed: September 20, 2007
    Publication date: June 19, 2008
    Inventors: Paul Bamborough, Michael David Barker, Sebastien Andre Campos, Richard Peter Charles Cousins, Paul Faulder, Heather Hobbs, Duncan Stuart Holmes, Michael John Johnston, John Liddle, Jeremy John Payne, John Martin Pritchard, Caroline Whitworth
  • Pyrrolidine derivatives as factor XA inhibitors
    Patent number: 7326785
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: February 5, 2008
    Assignee: Glaxo Group Limited
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • Pyrrolidin-2-one derivatives as inhibitors of factor xa
    Patent number: 7282497
    Abstract: The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: October 16, 2007
    Assignee: Glaxo Group Limited
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • PYRROLIDINE DERIVATIVES AS FACTOR XA INHIBITORS
    Publication number: 20070155745
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: October 11, 2006
    Publication date: July 5, 2007
    Inventors: Chuen Chan, Julie Hamblin, Henry Kelly, Nigel King, Andrew Mason, Vipulkumar Patel, Stefan Senger, Gita Shah, Nigel Watson, Helen Weston, Caroline Whitworth, Robert Young
  • PYRROLIDINE DERIVATIVES AS FACTOR XA INHIBITORS
    Publication number: 20070142375
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: October 11, 2006
    Publication date: June 21, 2007
    Inventors: Chuen CHAN, Julie Hamblin, Henry Kelly, Nigel King, Andrew Mason, Vipulkumar Patel, Stefan Senger, Gita Shah, Nigel Watson, Helen Weston, Caroline Whitworth, Robert Young
  • Pyrrolidin-2-one derivatives as inhibitors of factor xa
    Patent number: 7226929
    Abstract: The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: June 5, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • Pyrrolidine derivatives as Factor Xa inhibitors
    Patent number: 7186717
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: March 6, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • Pyrrolidin-2-one derivatives as inhibitors of factor Xa
    Patent number: 7084139
    Abstract: The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: August 1, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • Chemical compounds
    Publication number: 20060160886
    Abstract: The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: March 17, 2006
    Publication date: July 20, 2006
    Inventors: Chuen Chan, Julie Hamblin, Henry Kelly, Nigel King, Andrew Mason, Vipulkumar Patel, Stefan Senger, Gita Shah, Nigel Watson, Helen Weston, Caroline Whitworth, Robert Young
  • Chemical compounds
    Publication number: 20060160885
    Abstract: The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: March 17, 2006
    Publication date: July 20, 2006
    Inventors: Chuen Chan, Julie Hamblin, Henry Kelly, Nigel King, Andrew Mason, Vipulkumar Patel, Stefan Senger, Gita Shah, Nigel Watson, Helen Weston, Caroline Whitworth, Robert Young
  • Pyrrolidine derivatives as factor xa inhibitors
    Publication number: 20050107379
    Abstract: The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: June 6, 2002
    Publication date: May 19, 2005
    Inventors: Chuen Chan, Julie Hamblin, Henry Kelly, Nigel King, Andrew Mason, Vipulkumar Patel, Stefan Senger, Gita Shah, Nigel Watson, Helen Weston, Caroline Whitworth, Robert Young
  • Pyrrolidin-2-one derivatives as inhibitors of factor xa
    Publication number: 20040152697
    Abstract: The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: December 3, 2003
    Publication date: August 5, 2004
    Inventors: Chuen Chan, Julie Nicole Hamblin, Henry Anderson Kelly, Nigel Paul King, Andrew McMurtrie Mason, Vipulkumar Kantibhai Patel, Stefan Senger, Gita Punjabhai Shah, Nigel Stephen Watson, Helen Elisabeth Weston, Caroline Whitworth, Robert John Young
  • 2-(purin-9-yl)-Tetrahydrofuran-3,4-diol derivatives
    Patent number: 6534486
    Abstract: A series of 2-(Purin-9-yl)-tetrahydrofuran-3,4-diol derivatives with broad anti-inflammatory properties which inhibit leukocyte recruitment and activation and which are agonists of the adenosine 2a receptor are described.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: March 18, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: David George Allen, Chuen Chan, Caroline Mary Cook, Richard Peter Charles Cousins, Brian Cox, Hazel Joan Dyke, Frank Ellis, Joanna Victoria Geden, Heather Hobbs, Suzanne Elaine Keeling, Alison Judith Redgrave, Stephen Swanson, Caroline Whitworth, David Bays