Patents by Inventor Caroline Woo

Caroline Woo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS FOR DELIVERY OF OLIGONUCLEOTIDES TO LUNG CELLS
    Publication number: 20230062603
    Abstract: The present disclosure provides a method of pulmonarily administering an oligonucleotide to lung cells. In some embodiments, the disclosure provides formulations that comprise an oligonucleotide that is complementary to a target gene in lung cells and a lipid nanoparticle. Methods of the present disclosure are useful in modifying expression of target genes associated with chronic obstructive pulmonary disease, asthma, and pulmonary fibrosis.
    Type: Application
    Filed: January 6, 2021
    Publication date: March 2, 2023
    Applicant: Translate Bio MA, Inc.
    Inventors: Balkrishen Bhat, Brian Bettencourt, Saswata Karmakar, Caroline Woo, John Androsavich, Shrirang Karve
  • METHODS FOR IDENTIFYING AND TARGETING NON-CODING RNA SCAFFOLDS
    Publication number: 20190055553
    Abstract: Aspects of the disclosure provide steric-blocking oligonucleotide-based methods of modulating expression of target genes, e.g., by targeting non-coding RNA scaffolds.
    Type: Application
    Filed: October 14, 2016
    Publication date: February 21, 2019
    Applicant: TRANSLATE BIO MA, INC.
    Inventors: James BARSOUM, Caroline WOO
  • COMPOSITIONS AND METHODS FOR MODULATING RNA
    Publication number: 20150050738
    Abstract: Aspects of the invention relate to methods for increasing gene expression in a targeted manner. In some embodiments, methods and compositions are provided that are useful for posttranscriptionally altering protein and/or RNA levels in a targeted manner. Aspects of the invention disclosed herein provide methods and compositions that are useful for protecting RNAs from degradation (e.g., exonuclease mediated degradation).
    Type: Application
    Filed: August 15, 2014
    Publication date: February 19, 2015
    Applicant: RaNA Therapeutics, Inc.
    Inventors: Fatih Ozsolak, Caroline Woo