Patents by Inventor Carolyn W. Grady

Carolyn W. Grady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel process
    Publication number: 20030004352
    Abstract: A process for the manufacture of the (−) trans piperidine carbinol (1) by a process comprising contacting a racemic mixture of the piperidine carbinol in solution with (−)-ditoluoyltartaric acid, crystallising the (−) -ditoluoyltartaric acid salt of the piperidine carbinol, isolating the crystalline salt and neutralising the crystalline salt to regenerate the (−) trans isomer of the piperidine carbinol and the (−)-ditoluoyltartaric acid, which is characterised by one or more of the following steps: (1) combining solutions of the racemic piperidine carbinol and (−)-ditoluoyltartaric acid in acetone so that the combined solution contains 2-3 % wt/wt of water, (2) consolidating the chiral salt crystallisation at from 30 to 40° C., (3) cooling the crystallisation mixture to from 3 to 7° C. before isolating the chiral salt, (4) regenerating the (−) trans piperidine carbinol at a pH of from 10.5 to 11.
    Type: Application
    Filed: June 10, 2002
    Publication date: January 2, 2003
    Inventors: Christopher S. Brook, Alan D. Curzons, Carolyn W. Grady, Anthony J. O'Connor
  • 2-?2-(Dimethylamino)ethyl!-8,8-dipropyl-2-azaspiro?4.5!decane dimaleate
    Patent number: 5952365
    Abstract: The present invention is directed to an improved antihyperlipidemic agent, the dimaleate salt of 2-?2-(dimethylamino)ethyl!-8,8-dipropyl-2-azaspiro?4.5!decane.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: September 14, 1999
    Assignee: AnorMED Inc.
    Inventors: Raymond E Dagger, Carolyn W Grady
  • N,N-dimethyl-8,8-dipropyl-2-azaspiro?4.5!decane-2-propanamine dimaleate
    Patent number: 5939450
    Abstract: An improved immunomodulatory agent, the dimaleate salt of N,N-dimethyl-8,8-dipropyl-2-azaspiro?4.5!decane-2-propanamine.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: August 17, 1999
    Assignee: AnorMED Inc.
    Inventors: Raymond E Dagger, Carolyn W Grady
  • N, N-diethyl-8, 8-dipropyl-2-azaspiro?4.5! decane-2-propanamine
    Patent number: 5744495
    Abstract: An improved immumomodulatory agent, the dimaleate salt of N,N-diethyl-8,8-dipropyl-2-azaspiro?4.5!decane-2-propanamine.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: April 28, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Raymond E. Dagger, Carolyn W. Grady