Abstract: The invention provides isolated antibodies that specifically bind human P210 BCR-ABL fusion protein, but do not bind the respective wild type BCR and c-ABL proteins. The detection of this fusion protein is relevant to CML and other diseases characterized by the P210 BCR-ABL translocation. Also provided are methods for determining the level or expression of P210 BCR-ABL in a biological sample, or identifying a compound that modulates such expression, by using the disclosed BCR-ABL specific antibodies.

Abstract: A portable saliva compensation device is provided with a portable carrying case holding a vacuum pump, and a portable power supply for providing power to vacuum pump. A programmable electrical control circuit is connected to the portable power supply and the pump. A saliva collection device is provided having a portion thereof positionable inside user's mouth for collecting excess saliva and conveying it to a hollow tube connecting between the saliva collection device and the vacuum pump. An activation operably coupled to the electrical control circuit to activate the vacuum pump when saliva is to be collected from the user's mouth. This draws the saliva from the collection device through said hollow tube and into a collection reservoir.

Abstract: A portable saliva compensation device is provided with a portable carrying case holding a vacuum pump, and a portable power supply for providing power to vacuum pump. An electrical control circuit is connected to the portable power supply and the pump. A saliva collection device is positioned at or below a user's mouth for collecting excess saliva and conveying it to a hollow tube connecting between the saliva collection device and the vacuum pump. A saliva detection switch in the saliva collection device is coupled to the electrical control circuit to activate the vacuum pump when saliva is detected in the saliva collection device. This draws the saliva from the collection device through said hollow tube and into a collection reservoir.