Abstract: A glass tube for pharmaceutical containers is provided. The tube has an inner surface at an inner diameter, an outer surface with an outer diameter, a first end defining a first closed end, a second end defining a first closed end, a first location 400 mm from the first end, a first intermediate location 15 mm from the first end, and a ventilation hole at a first vicinity. The first vicinity is between the first intermediate location and the first location. The glass tube can have a ratio of an integrated Na2F+ signal to an integrated 30Si+ signal of at least 0.10, where the integrated Na2F+signal and the integrated 30Si+signal are integrated over a depth of 100 nm. The glass tube can have a ratio between a fluorescence emission determined at a first vicinity and a fluorescence emission determined at a middle section of at least 0.6.

Abstract: A glass tube for pharmaceutical containers is provided. The tube has an inner surface at an inner diameter, an outer surface with an outer diameter, a first end defining a first closed end, a second end defining a first closed end, a first location 400 mm from the first end, a first intermediate location 15 mm from the first end, and a ventilation hole at a first vicinity. The first vicinity is between the first intermediate location and the first location. The glass tube can have a ratio of an integrated Na2F+ signal to an integrated 30Si+ signal of at least 0.10, where the integrated Na2F+ signal and the integrated 30Si+ signal are integrated over a depth of 100 nm. The glass tube can have a ratio between a fluorescence emission determined at a first vicinity and a fluorescence emission determined at a middle section of at least 0.6.

Abstract: A method for the manufacture of a glass tube with closed ends includes: providing a glass tube with open ends including a first open end and a second open end; closing the first open end of the glass tube while introducing a gas into the glass tube through the second open end; opening a ventilation hole in a wall of the glass tube near one of the open ends; and closing the second open end.

Abstract: A glass tube for pharmaceutical containers is provided. The tube has an inner surface at an inner diameter, an outer surface with an outer diameter, a first end defining a first closed end, a second end defining a first closed end, a first location 400 mm from the first end, a first intermediate location 15 mm from the first end, and a ventilation hole at a first vicinity. The first vicinity is between the first intermediate location and the first location. The glass tube can have a ratio of an integrated Na2F+ signal to an integrated 30Si+ signal of at least 0.10, where the integrated Na2F+ signal and the integrated 30Si+ signal are integrated over a depth of 100 nm. The glass tube can have a ratio between a fluorescence emission determined at a first vicinity and a fluorescence emission determined at a middle section of at least 0.6.