Publication number: 20220168470
Abstract: A system for the therapeutic treatment of joints comprising a composite material comprising a biodegradable polymer matrix and a plurality of piezoelectric particles adapted to generate local electric charges in response to an external stimulation made by means of ultrasound, said plurality of piezoelectric particles being dispersed in the matrix. The composite material also comprises a plurality of stamina cells dispersed in the biodegradable polymer matrix and a plurality of carbon-based particles. The system also comprises a releasing device, arranged to deposit the composite material in a joint cavity at predetermined areas of the cartilage, and a stimulator device arranged to emit ultrasound at a predetermined frequency, a predetermined intensity and for a predetermined time of application, in such a way that, when the device is located near a joint wherein the composite material has been deposited, said ultrasound stimulate the plurality of piezoelectric particles.
Type:
Application
Filed:
February 25, 2020
Publication date:
June 2, 2022
Applicants:
VIMEX SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (VIMEX), H&D WIRELESS AB, PLASMACHEM PRODUKTIONS UND HANDEL GMBH, IMAGE GUIDED THERAPY SA, ISTITUTO ORTOPEDICO RIZZOLI, BAR ILAN UNIVERSITY, SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA
Inventors:
Leonardo RICOTTI, Lorenzo VANNOZZI, Andrea CAFARELLI, Gilbert Daniel NESSIM, Gina LISIGNOLI, Aharon WECHSLER, Erik Jean-Claude DUMONT, Carsten JOST, Tomasz GAPINSKI, Pär BERGSTEN, Elena GABUSI, Milena FINI, Matilde TSCHON, Alessandro RUSSO, Stefano ZAFFAGNINI, Riccardo MELICONI, Yirij FEDUTIK, Krzysztof Stanislaw LENARTOWICZ, Åke JERNBERGER, Yonatan SHACHAF, Magnus ERIKSSON
Patent number: 6852893
Abstract: The invention relates to a method for oxidizing substrates such as hydrocarbons, waxes or soot. The method involves the use of a compound of formula (I) in which: R1 and R2 represent H, an aliphatic or aromatic alkoxy radical, carboxyl radical, alkoxycarbonyl radical or hydrocarbon radical, each having 1 to 20 hydrocarbon atoms, SO3H, NH2, OH, F, Cl, Br, I and/or NO2, whereby R1 and R2 designate identical or different radicals or R1 and R2 can be linked to one another via a covalent bonding; Q1 and Q2 represent C, CH, N, CR5, each being the same or different; X and Z represent C, S, CH2, each being the same or different; Y represents O and OH; k=0, 1, 2; l=0, 1, 2; m=1 to 3, and; R5 represents one of the meanings of R1. Said compound is used as a catalyst in the presence of a radical initiator, whereby the molar ratio of the catalyst to the hydrocarbon is less than 10 mol %. Peroxy compounds or azo compounds can be used as the radical initiator. Preferred substrates are aliphatic or aromatic hydrocarbons.
Type:
Grant
Filed:
March 22, 2001
Date of Patent:
February 8, 2005
Assignee:
Creavis Gesellschaft fuer Technologie and Innovation mbH
Inventors:
Adolf Kühnle, Mark Duda, Carsten Jost, Guido Fries, Jochen Kirchhoff, Thomas Schiffer, Roger Arthur Sheldon, Sasidharan Manickam, Isabella W. C. E. Arends