Patents by Inventor Carsten Mailand Hjort
Carsten Mailand Hjort has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7919275Abstract: An isolated mutant host cell produced by disrupting or deleting, in a parent cell, a nucleic acid sequence encoding an oxaloacetate hydrolase, or a promoter thereof, which results in the mutant cell producing less of the oxaloacetate hydrolase than the parent cell is disclosed. The disclosure also relates to recombinant methods for producing the products such as polypeptides.Type: GrantFiled: March 8, 2010Date of Patent: April 5, 2011Assignee: Novozymes A/SInventors: Carsten Mailand Hjort, Henrik Pedersen, Jens Nielsen
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Publication number: 20100173390Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having oxaloacetate hydrolase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as recombinant methods for producing the polypeptides.Type: ApplicationFiled: March 8, 2010Publication date: July 8, 2010Applicant: Novozymes A/SInventors: Carsten Mailand Hjort, Henrik Pedersen
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Patent number: 7172887Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having oxaloacetate hydrolase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as recombinant methods for producing the polypeptides.Type: GrantFiled: May 4, 2005Date of Patent: February 6, 2007Assignee: Novozymes A/SInventors: Carsten Mailand Hjort, Henrik Pedersen
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Patent number: 6936438Abstract: The present invention relates to methods of producing a polypeptide comprising culturing a mutant of a parent cell, wherein the mutant produces less oxaloacetate hydrolase than the parent cell, wherein the oxaloacetate hydrolase (i) has an amino acid sequence that has at least 90% identity with amino acids 1-341 of SEQ ID NO: 2: (ii) is encoded by a nucleic acid sequence having at least 90% homology with a nucleotide sequence comprising nuclotides 1157-1411, 1504-1651 and 1764-2383 of SEQ ID NO: 1: (iii) is encoded by a nucleic acid sequence which hybridizes under high stringency conditions with the nucleic acid sequence of SEQ ID NO: 1, the cDNA sequence of SEQ ID NO: 1, the complementary strand of SEQ ID NO: 1, and/or the complementary strand of the cDNA sequence of SEQ ID NO: 1: and/or (iv) a subsequence of one or both of (i) and (ii), wherein the subsequence encodes a fragment that has oxaloacetate hydrolase activity.Type: GrantFiled: January 3, 2003Date of Patent: August 30, 2005Assignee: Novozymes A/SInventors: Carsten Mailand Hjort, Henrik Pedersen
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Publication number: 20030148464Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having oxaloacetate hydrolase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as recombinant methods for producing the polypeptides.Type: ApplicationFiled: January 3, 2003Publication date: August 7, 2003Applicant: Novozymes A/SInventors: Carsten Mailand Hjort, Henrik Pedersen
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Publication number: 20030119167Abstract: The present invention relates to cellulase preparations consisting essentially of a homogeneous endoglucanase component which is immunoreactive with an antibody raised against a highly purified ˜43 kD endoglucanase derived from Humicola insolens, DSM 1800, or which is homogenous to said ˜43 kD endoglucanase, may be employed in the treatment cellulose-containing fabrics for harshness reduction or color clarification or to provide a localized variation in the color of such fabrics, or it may be employed in the treatment of paper pulp.Type: ApplicationFiled: May 3, 2002Publication date: June 26, 2003Applicant: Novozymes A/SInventors: Grethe Rasmussen, Jan Moller Mikkelsen, Martin Schulein, Shamkant Anant Patkar, Fred Hagen, Carsten Mailand Hjort, Sven Hastrup
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Patent number: 6544765Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having oxaloacetate hydrolase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as recombinant methods for producing the polypeptides.Type: GrantFiled: February 10, 2000Date of Patent: April 8, 2003Assignee: Novozymes, A/SInventors: Carsten Mailand Hjort, Henrik Pedersen
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Patent number: 6423524Abstract: The present invention relates to cellulase preparations consisting essentially of a homogeneous endoglucanase component. The cellulase preparation may be employed in the treatment of cellulose-containing fabrics for harshness reduction, for color clarification, or to provide a localized variation in the color of such fabrics, or in the treatment of paper pulp.Type: GrantFiled: November 10, 1998Date of Patent: July 23, 2002Assignee: Novo Nordisk A/SInventors: Fred Hagen, Carsten Mailand Hjort, Sven Hastrup
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Patent number: 6346244Abstract: The present invention relates to protein disulfide isomerases which are encoded by a nucleic acid sequence which hybridizes with (i) the DNA sequence of SEQ ID NO:1 or (ii) the DNA sequence of SEQ ID NO:2, under the following conditions: presoaking in 5×SSC and prehybridizing for 1 h at ˜40° C. in a solution of 5×SSC, 5×Denhardt's solution, 50 mM sodium phosphate, pH 6.8, and 50 &mgr;g of denatured sonicated calf thymus DNA, followed by hybridization in the same solution supplemented with 50 &mgr;Ci 32-P-dCTP labelled probe for 18 h at ˜40° C. followed by washing three times in 2×SSC, 0.2% SDS at 40° C. for 30 minutes; and fragments thereof. The present invention also relates to DNA sequences encoding the protein disulfide isomerases, compositions comprising said protein disulfide isomerases and methods of use thereof.Type: GrantFiled: March 4, 1999Date of Patent: February 12, 2002Assignee: Novozymes A/SInventor: Carsten Mailand Hjort
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Publication number: 20010036910Abstract: A cellulase preparation consisting essentially of a homogeneous endoglucanase component which is immunoreactive with an antibody raised against a highly purified ˜43kD endoglucanase derived from Humicola insolens, DSM 1800, or which is homogenous to said 43kD endoglucanase, may be employed in the treatment cellulose-containing fabrics for harshness reduction or color clarification or to provide a localized variation in the color of such fabrics, or it may be employed in the treatment of paper pulp.Type: ApplicationFiled: December 13, 2000Publication date: November 1, 2001Inventors: Grethe Rasmussen, Jan Moller Mikkelsen, Martin Schulein, Shamkant Anant Patkar, Fred Hagen, Carsten Mailand Hjort, Sven Hastrup
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Patent number: 5948672Abstract: A cellulase preparation consisting essentially of a homogeneous endoglucanase component which is immunoreactive with an antibody raised against a highly purified .about.43 kD endoglucanase derived from Humicola insolens, DSM 1800, or which is homogeneous to said .about.43 kD endoglucanase, may be employed in the treatment cellulose-containing fabrics for harshness reduction or color clarification or to provide a localized variation in the color of such fabrics, or it may be employed in the treatment of paper pulp.Type: GrantFiled: February 14, 1995Date of Patent: September 7, 1999Assignee: Novo Nordisk A/SInventors: Grethe Rasmussen, Jan M.o slashed.ller Mikkelsen, Martin Schulein, Shamkant Anant Patkar, Fred Hagen, Carsten Mailand Hjort, Sven Hastrup
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Patent number: 5879664Abstract: A fungal protein disulfide isomerase obtainable from fungal species belonging to Aspergillus, especially A. oryzae, or A. niger, is disclosed. Furthermore sequences for recombinant production of the protein disulfide isomerase are disclosed.Type: GrantFiled: December 11, 1995Date of Patent: March 9, 1999Assignee: Novo Nordisk A/SInventor: Carsten Mailand Hjort
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Patent number: 5763254Abstract: The present invention relates to isolated and purified cellulose- or hemicellulose-degrading enzymes, comprising a catalytically active domain, a carbohydrate binding domain and a linking B region which operably links the catalytically active domain and the carbohydrate binding domain, wherein the carbohydrate binding domain has the following core sequence: ##STR1## wherein the enzyme is endogenous to a strain of a fungus other than Trichoderma or Phanerochaete.Type: GrantFiled: June 7, 1995Date of Patent: June 9, 1998Assignee: Novo Nordisk A/SInventors: Helle Fabricius Woldike, Fred Hagen, Carsten Mailand Hjort, Sven Hastrup
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Patent number: 5686593Abstract: The present invention relates to cellulose- or hemicellulose-degrading enzymes which is derivable from a fungus other than Trichoderma or Phanerochaete, and which comprises a carbohydrate binding domain homologous to a terminal A region of Trichoderma reesei cellulases, which carbohydrate binding domain comprises the following amino acid sequence. ##STR1## or a subsequence thereof capable of effecting binding of the enzyme to an insoluble cellulosic or hemicellulosic substrate.Type: GrantFiled: June 7, 1995Date of Patent: November 11, 1997Assignee: Novo Nordisk A/SInventors: Helle Fabricius Woldike, Fred Hagen, Carsten Mailand Hjort, Sven Hastrup